trichostatin A-4526 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the trichostatin A-4526 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ADAM23 ADAM metallopeptidase domain 23
ADAP2 ArfGAP with dual PH domains 2
ALG12 ALG12, alpha-1,6-mannosyltransferase
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ATF6B activating transcription factor 6 beta
ATXN7L1 ataxin 7-like 1
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BAGE B melanoma antigen
BMP1 bone morphogenetic protein 1
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
BTG2 BTG family, member 2
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCDC40 coiled-coil domain containing 40
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CEP162 centrosomal protein 162kDa
CGA glycoprotein hormones, alpha polypeptide
CISH cytokine inducible SH2-containing protein
CLDN1 claudin 1
CSHL1 chorionic somatomammotropin hormone-like 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DCTN2 dynactin 2 (p50)
DGKQ diacylglycerol kinase, theta 110kDa
DKK3 dickkopf WNT signaling pathway inhibitor 3
DPY19L1 dpy-19-like 1 (C. elegans)
ELN elastin
FBXO22 F-box protein 22
FGF1 fibroblast growth factor 1 (acidic)
FGF5 fibroblast growth factor 5
FGFR1 fibroblast growth factor receptor 1
FLT1 fms-related tyrosine kinase 1
FLT4 fms-related tyrosine kinase 4
FRS3 fibroblast growth factor receptor substrate 3
GK glycerol kinase
GMPR guanosine monophosphate reductase
GPNMB glycoprotein (transmembrane) nmb
GREB1L growth regulation by estrogen in breast cancer-like
HBS1L HBS1-like translational GTPase
HDAC11 histone deacetylase 11
HES2 hes family bHLH transcription factor 2
HESX1 HESX homeobox 1
HPGDS hematopoietic prostaglandin D synthase
HRG histidine-rich glycoprotein
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
ICA1 islet cell autoantigen 1, 69kDa
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IL12RB1 interleukin 12 receptor, beta 1
IL15 interleukin 15
ITM2A integral membrane protein 2A
JAG1 jagged 1
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KRT34 keratin 34, type I
KSR1 kinase suppressor of ras 1
LIFR leukemia inhibitory factor receptor alpha
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
LOXL3 lysyl oxidase-like 3
LY96 lymphocyte antigen 96
MN1 meningioma (disrupted in balanced translocation) 1
MRPL41 mitochondrial ribosomal protein L41
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NQO1 NAD(P)H dehydrogenase, quinone 1
NRCAM neuronal cell adhesion molecule
NRP2 neuropilin 2
NYNRIN NYN domain and retroviral integrase containing
OGFR opioid growth factor receptor
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PEX16 peroxisomal biogenesis factor 16
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
PTPRH protein tyrosine phosphatase, receptor type, H
PYY peptide YY
SCEL sciellin
SCN11A sodium channel, voltage gated, type XI alpha subunit
SIGLEC6 sialic acid binding Ig-like lectin 6
SIX3 SIX homeobox 3
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC22A14 solute carrier family 22, member 14
SOS2 son of sevenless homolog 2 (Drosophila)
SPTBN5 spectrin, beta, non-erythrocytic 5
TBC1D30 TBC1 domain family, member 30
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TIMELESS timeless circadian clock
TLR4 toll-like receptor 4
TM4SF1 transmembrane 4 L six family member 1
TMEM212 transmembrane protein 212
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TTC38 tetratricopeptide repeat domain 38
UBE2I ubiquitin-conjugating enzyme E2I
VAV3 vav 3 guanine nucleotide exchange factor

decreased expression

Symbol Name
ACBD4 acyl-CoA binding domain containing 4
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARRB2 arrestin, beta 2
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATAT1 alpha tubulin acetyltransferase 1
AXIN1 axin 1
BAAT bile acid CoA:amino acid N-acyltransferase
BCAS3 breast carcinoma amplified sequence 3
BTF3P12 basic transcription factor 3 pseudogene 12
C4ORF19 chromosome 4 open reading frame 19
C5ORF45 chromosome 5 open reading frame 45
C7ORF69 chromosome 7 open reading frame 69
CA5BP1 carbonic anhydrase VB pseudogene 1
CAMTA2 calmodulin binding transcription activator 2
CCNJ cyclin J
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CFAP69 cilia and flagella associated protein 69
CHPF chondroitin polymerizing factor
CLSPN claspin
CNN2 calponin 2
CPED1 cadherin-like and PC-esterase domain containing 1
CPNE7 copine VII
CREB5 cAMP responsive element binding protein 5
CUZD1 CUB and zona pellucida-like domains 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DEPTOR DEP domain containing MTOR-interacting protein
DNAL4 dynein, axonemal, light chain 4
EAF2 ELL associated factor 2
EFNB1 ephrin-B1
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ETV4 ets variant 4
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FPGS folylpolyglutamate synthase
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GUSBP3 glucuronidase, beta pseudogene 3
HCFC2 host cell factor C2
HDAC7 histone deacetylase 7
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H2AM histone cluster 1, H2am
HOXA1 homeobox A1
HOXA4 homeobox A4
HOXC13 homeobox C13
IFI35 interferon-induced protein 35
IL17RA interleukin 17 receptor A
INF2 inverted formin, FH2 and WH2 domain containing
INPPL1 inositol polyphosphate phosphatase-like 1
IRF1 interferon regulatory factor 1
JAM3 junctional adhesion molecule 3
KIAA0319L KIAA0319-like
KIAA0556 KIAA0556
LOC390998 ribosomal protein L10 pseudogene
LOC729164 hCG1732469
LRRK1 leucine-rich repeat kinase 1
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LZTR1 leucine-zipper-like transcription regulator 1
MAN2C1 mannosidase, alpha, class 2C, member 1
MAST3 microtubule associated serine/threonine kinase 3
MFSD6 major facilitator superfamily domain containing 6
MGP matrix Gla protein
MLYCD malonyl-CoA decarboxylase
MOSPD3 motile sperm domain containing 3
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MRPL28 mitochondrial ribosomal protein L28
MT1M metallothionein 1M
MXD3 MAX dimerization protein 3
NOD1 nucleotide-binding oligomerization domain containing 1
PCOLCE procollagen C-endopeptidase enhancer
PER3 period circadian clock 3
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PRSS53 protease, serine, 53
RAB4B RAB4B, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RIN1 Ras and Rab interactor 1
RNF122 ring finger protein 122
RPS17P5 ribosomal protein S17 pseudogene 5
RUSC2 RUN and SH3 domain containing 2
SETD8 SET domain containing (lysine methyltransferase) 8
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SND1-IT1 SND1 intronic transcript 1
SPEG SPEG complex locus
SRD5A3 steroid 5 alpha-reductase 3
STX5 syntaxin 5
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TBC1D8B TBC1 domain family, member 8B (with GRAM domain)
TEP1 telomerase-associated protein 1
TUBGCP5 tubulin, gamma complex associated protein 5
USP19 ubiquitin specific peptidase 19
USP20 ubiquitin specific peptidase 20
VASH1 vasohibin 1
VWA1 von Willebrand factor A domain containing 1
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZMAT5 zinc finger, matrin-type 5
ZNF442 zinc finger protein 442
ZRSR2 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2