trichostatin A-2672 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the trichostatin A-2672 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
ADAM28 ADAM metallopeptidase domain 28
ADGRL2 adhesion G protein-coupled receptor L2
ANG angiogenin, ribonuclease, RNase A family, 5
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARHGAP5 Rho GTPase activating protein 5
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BIK BCL2-interacting killer (apoptosis-inducing)
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2
CD209 CD209 molecule
CD300C CD300c molecule
CD59 CD59 molecule, complement regulatory protein
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEP70 centrosomal protein 70kDa
CLGN calmegin
COL14A1 collagen, type XIV, alpha 1
CPNE3 copine III
CREB3 cAMP responsive element binding protein 3
CYFIP2 cytoplasmic FMR1 interacting protein 2
DCAF15 DDB1 and CUL4 associated factor 15
DDAH2 dimethylarginine dimethylaminohydrolase 2
DFNA5 deafness, autosomal dominant 5
DNAH17 dynein, axonemal, heavy chain 17
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DOCK4 dedicator of cytokinesis 4
DSP desmoplakin
DZIP3 DAZ interacting zinc finger protein 3
EFNB2 ephrin-B2
EGR2 early growth response 2
EPAS1 endothelial PAS domain protein 1
EPHB2 EPH receptor B2
F11R F11 receptor
FLOT1 flotillin 1
FUCA1 fucosidase, alpha-L- 1, tissue
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GCH1 GTP cyclohydrolase 1
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
H1F0 H1 histone family, member 0
H2AFJ H2A histone family, member J
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HOXA7 homeobox A7
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
INCENP inner centromere protein antigens 135/155kDa
JPH3 junctophilin 3
KCTD20 potassium channel tetramerization domain containing 20
KDELC1 KDEL (Lys-Asp-Glu-Leu) containing 1
KIAA0895 KIAA0895
KIF5C kinesin family member 5C
LPAR6 lysophosphatidic acid receptor 6
LRRN3 leucine rich repeat neuronal 3
MAN1A1 mannosidase, alpha, class 1A, member 1
MARCKS myristoylated alanine-rich protein kinase C substrate
MCTP2 multiple C2 domains, transmembrane 2
MEF2C myocyte enhancer factor 2C
METTL7A methyltransferase like 7A
MOB3B MOB kinase activator 3B
MPZL1 myelin protein zero-like 1
MTUS1 microtubule associated tumor suppressor 1
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYH4 myosin, heavy chain 4, skeletal muscle
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NCAM1 neural cell adhesion molecule 1
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OASL 2'-5'-oligoadenylate synthetase-like
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PARD6A par-6 family cell polarity regulator alpha
PCDH9 protocadherin 9
PCNXL2 pecanex-like 2 (Drosophila)
PFN2 profilin 2
PHTF2 putative homeodomain transcription factor 2
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLD3 phospholipase D family, member 3
PLEKHA5 pleckstrin homology domain containing, family A member 5
PLS1 plastin 1
POU4F1 POU class 4 homeobox 1
PPAP2B phosphatidic acid phosphatase type 2B
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAB6B RAB6B, member RAS oncogene family
RCE1 Ras converting CAAX endopeptidase 1
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS5 regulator of G-protein signaling 5
RIMS3 regulating synaptic membrane exocytosis 3
RNASE4 ribonuclease, RNase A family, 4
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
SCML1 sex comb on midleg-like 1 (Drosophila)
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SP110 SP110 nuclear body protein
STON1 stonin 1
STX11 syntaxin 11
STXBP1 syntaxin binding protein 1
TM6SF2 transmembrane 6 superfamily member 2
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TPD52L1 tumor protein D52-like 1
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TRPS1 trichorhinophalangeal syndrome I
TUBB2A tubulin, beta 2A class IIa
TUFT1 tuftelin 1
ZSCAN16 zinc finger and SCAN domain containing 16

decreased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ADGRE3 adhesion G protein-coupled receptor E3
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
ANKRD7 ankyrin repeat domain 7
APOC4 apolipoprotein C-IV
ART1 ADP-ribosyltransferase 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BCAS3 breast carcinoma amplified sequence 3
BDH1 3-hydroxybutyrate dehydrogenase, type 1
C19ORF73 chromosome 19 open reading frame 73
C22ORF46 chromosome 22 open reading frame 46
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CD34 CD34 molecule
CDK20 cyclin-dependent kinase 20
CEMP1 cementum protein 1
CGA glycoprotein hormones, alpha polypeptide
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CIDEB cell death-inducing DFFA-like effector b
CNN1 calponin 1, basic, smooth muscle
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
COL4A2 collagen, type IV, alpha 2
CRELD1 cysteine-rich with EGF-like domains 1
CROT carnitine O-octanoyltransferase
CXCL2 chemokine (C-X-C motif) ligand 2
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DCAF13 DDB1 and CUL4 associated factor 13
DDN dendrin
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DEPTOR DEP domain containing MTOR-interacting protein
DPH2 DPH2 homolog (S. cerevisiae)
DSCAM Down syndrome cell adhesion molecule
EDAR ectodysplasin A receptor
EMILIN2 elastin microfibril interfacer 2
ENDOG endonuclease G
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EPHB6 EPH receptor B6
EXO5 exonuclease 5
FBXL2 F-box and leucine-rich repeat protein 2
FGF6 fibroblast growth factor 6
FZD4 frizzled class receptor 4
GGTLC1 gamma-glutamyltransferase light chain 1
GNG4 guanine nucleotide binding protein (G protein), gamma 4
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BH histone cluster 1, H2bh
HPR haptoglobin-related protein
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IQCC IQ motif containing C
JUNB jun B proto-oncogene
KDM8 lysine (K)-specific demethylase 8
KPTN kaptin (actin binding protein)
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LOXL3 lysyl oxidase-like 3
LPPR3 lipid phosphate phosphatase-related protein type 3
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAPK12 mitogen-activated protein kinase 12
MCM9 minichromosome maintenance complex component 9
MEPCE methylphosphate capping enzyme
METTL1 methyltransferase like 1
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NIPAL2 NIPA-like domain containing 2
NLGN1 neuroligin 1
NOL6 nucleolar protein 6 (RNA-associated)
NR1D2 nuclear receptor subfamily 1, group D, member 2
NXF2 nuclear RNA export factor 2
ORM1 orosomucoid 1
PBLD phenazine biosynthesis-like protein domain containing
PPARG peroxisome proliferator-activated receptor gamma
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PRDM12 PR domain containing 12
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PUS1 pseudouridylate synthase 1
PYGB phosphorylase, glycogen; brain
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RGS19 regulator of G-protein signaling 19
RNF25 ring finger protein 25
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SARS2 seryl-tRNA synthetase 2, mitochondrial
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SLC12A8 solute carrier family 12, member 8
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SOCS2 suppressor of cytokine signaling 2
STAB2 stabilin 2
SYTL2 synaptotagmin-like 2
TAGLN transgelin
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMEM177 transmembrane protein 177
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TRAF2 TNF receptor-associated factor 2
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
WBSCR16 Williams-Beuren syndrome chromosome region 16
ZNF473 zinc finger protein 473
ZNF76 zinc finger protein 76