trichostatin A-2639 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the trichostatin A-2639 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ADD3 adducin 3 (gamma)
ADM adrenomedullin
AHNAK2 AHNAK nucleoprotein 2
ALDOC aldolase C, fructose-bisphosphate
ANG angiogenin, ribonuclease, RNase A family, 5
ARMCX2 armadillo repeat containing, X-linked 2
CCDC68 coiled-coil domain containing 68
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CFAP69 cilia and flagella associated protein 69
CLGN calmegin
CLMN calmin (calponin-like, transmembrane)
CORO1A coronin, actin binding protein, 1A
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CSRP2 cysteine and glycine-rich protein 2
CXADR coxsackie virus and adenovirus receptor
CYLD cylindromatosis (turban tumor syndrome)
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
DEGS1 delta(4)-desaturase, sphingolipid 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLX2 distal-less homeobox 2
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DPYSL4 dihydropyrimidinase-like 4
DUSP10 dual specificity phosphatase 10
EFNB3 ephrin-B3
EPOR erythropoietin receptor
FAM214B family with sequence similarity 214, member B
FAM46C family with sequence similarity 46, member C
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FKBP1B FK506 binding protein 1B, 12.6 kDa
FSCN1 fascin actin-bundling protein 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GEM GTP binding protein overexpressed in skeletal muscle
GLRX glutaredoxin (thioltransferase)
GRK5 G protein-coupled receptor kinase 5
GTF2B general transcription factor IIB
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HMOX1 heme oxygenase 1
HOXA1 homeobox A1
HPX hemopexin
IL21R interleukin 21 receptor
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JAKMIP2 janus kinase and microtubule interacting protein 2
KIAA0513 KIAA0513
KIF5C kinesin family member 5C
LIMA1 LIM domain and actin binding 1
LYST lysosomal trafficking regulator
MAP1B microtubule-associated protein 1B
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MARK4 MAP/microtubule affinity-regulating kinase 4
MBNL2 muscleblind-like splicing regulator 2
MITF microphthalmia-associated transcription factor
MMD monocyte to macrophage differentiation-associated
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NPC1 Niemann-Pick disease, type C1
NPIPB3 nuclear pore complex interacting protein family, member B3
NXN nucleoredoxin
PCDH9 protocadherin 9
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PRPH peripherin
PTPN1 protein tyrosine phosphatase, non-receptor type 1
RAB3A RAB3A, member RAS oncogene family
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS2 regulator of G-protein signaling 2
RNASE4 ribonuclease, RNase A family, 4
RND1 Rho family GTPase 1
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RUNDC3B RUN domain containing 3B
SAT1 spermidine/spermine N1-acetyltransferase 1
SEPP1 selenoprotein P, plasma, 1
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3GL3 SH3-domain GRB2-like 3
SIRT4 sirtuin 4
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLCO4C1 solute carrier organic anion transporter family, member 4C1
SPTAN1 spectrin, alpha, non-erythrocytic 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STARD5 StAR-related lipid transfer (START) domain containing 5
STK17A serine/threonine kinase 17a
STON1 stonin 1
STXBP1 syntaxin binding protein 1
TBC1D19 TBC1 domain family, member 19
TBXA2R thromboxane A2 receptor
TUBA4A tubulin, alpha 4a
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
WDR19 WD repeat domain 19
ZCCHC24 zinc finger, CCHC domain containing 24
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF204P zinc finger protein 204, pseudogene
ZNF224 zinc finger protein 224
ZNF778 zinc finger protein 778

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADGRA3 adhesion G protein-coupled receptor A3
ADNP activity-dependent neuroprotector homeobox
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
AMIGO2 adhesion molecule with Ig-like domain 2
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARHGAP11A Rho GTPase activating protein 11A
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ATAD3A ATPase family, AAA domain containing 3A
BANP BTG3 associated nuclear protein
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C2CD5 C2 calcium-dependent domain containing 5
C9ORF40 chromosome 9 open reading frame 40
CALHM2 calcium homeostasis modulator 2
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CBR3 carbonyl reductase 3
CCDC94 coiled-coil domain containing 94
CCND1 cyclin D1
CHMP6 charged multivesicular body protein 6
COIL coilin
CTCF CCCTC-binding factor (zinc finger protein)
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DEAF1 DEAF1 transcription factor
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13
EFNA1 ephrin-A1
EGR3 early growth response 3
ERN2 endoplasmic reticulum to nucleus signaling 2
ESRP2 epithelial splicing regulatory protein 2
EXOSC10 exosome component 10
FAM57A family with sequence similarity 57, member A
FOXA1 forkhead box A1
FOXD1 forkhead box D1
GATA3 GATA binding protein 3
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GDAP1 ganglioside induced differentiation associated protein 1
GINS3 GINS complex subunit 3 (Psf3 homolog)
GPR87 G protein-coupled receptor 87
GTF2I general transcription factor IIi
HYAL2 hyaluronoglucosaminidase 2
INHBB inhibin, beta B
IPP intracisternal A particle-promoted polypeptide
IRS1 insulin receptor substrate 1
IRX5 iroquois homeobox 5
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KCTD15 potassium channel tetramerization domain containing 15
KEAP1 kelch-like ECH-associated protein 1
MCM9 minichromosome maintenance complex component 9
MED15 mediator complex subunit 15
MEPCE methylphosphate capping enzyme
METTL8 methyltransferase like 8
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MSL1 male-specific lethal 1 homolog (Drosophila)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NME6 NME/NM23 nucleoside diphosphate kinase 6
NMI N-myc (and STAT) interactor
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
NUAK1 NUAK family, SNF1-like kinase, 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PHLDA3 pleckstrin homology-like domain, family A, member 3
POGK pogo transposable element with KRAB domain
PPAP2C phosphatidic acid phosphatase type 2C
PRNP prion protein
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
RPRD2 regulation of nuclear pre-mRNA domain containing 2
RWDD3 RWD domain containing 3
RXRA retinoid X receptor, alpha
SCAF8 SR-related CTD-associated factor 8
SCRN1 secernin 1
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SETD1B SET domain containing 1B
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SMG9 SMG9 nonsense mediated mRNA decay factor
SNHG3 small nucleolar RNA host gene 3
SREK1 splicing regulatory glutamine/lysine-rich protein 1
STC2 stanniocalcin 2
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TARBP2 TAR (HIV-1) RNA binding protein 2
THAP1 THAP domain containing, apoptosis associated protein 1
TMEM62 transmembrane protein 62
TRIB3 tribbles pseudokinase 3
TRIM16 tripartite motif containing 16
TRIM8 tripartite motif containing 8
TSKU tsukushi, small leucine rich proteoglycan
TUBA3C tubulin, alpha 3c
UCK2 uridine-cytidine kinase 2
USP21 ubiquitin specific peptidase 21
WDR13 WD repeat domain 13
WDR74 WD repeat domain 74
XBP1 X-box binding protein 1
ZHX2 zinc fingers and homeoboxes 2
ZIC1 Zic family member 1
ZNF253 zinc finger protein 253
ZNF254 zinc finger protein 254
ZNF692 zinc finger protein 692
ZNF787 zinc finger protein 787