tretinoin-2671 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the tretinoin-2671 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ACSL1 acyl-CoA synthetase long-chain family member 1
ADD3 adducin 3 (gamma)
ADM adrenomedullin
AIM2 absent in melanoma 2
ANGPTL4 angiopoietin-like 4
ARHGAP12 Rho GTPase activating protein 12
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ASRGL1 asparaginase like 1
ATXN2L ataxin 2-like
BCL6 B-cell CLL/lymphoma 6
BCL7B B-cell CLL/lymphoma 7B
C1ORF106 chromosome 1 open reading frame 106
CCL2 chemokine (C-C motif) ligand 2
CCNA1 cyclin A1
CCR1 chemokine (C-C motif) receptor 1
CD1D CD1d molecule
CD300A CD300a molecule
CD300C CD300c molecule
CD38 CD38 molecule
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLIC3 chloride intracellular channel 3
CLMN calmin (calponin-like, transmembrane)
COL4A2 collagen, type IV, alpha 2
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
CXCR5 chemokine (C-X-C motif) receptor 5
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DHRS3 dehydrogenase/reductase (SDR family) member 3
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
EFNB2 ephrin-B2
ENDOD1 endonuclease domain containing 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EXPH5 exophilin 5
FAM134B family with sequence similarity 134, member B
FAM13A family with sequence similarity 13, member A
FAM49B family with sequence similarity 49, member B
FBP1 fructose-1,6-bisphosphatase 1
FCMR Fc fragment of IgM receptor
FGF9 fibroblast growth factor 9
FGR FGR proto-oncogene, Src family tyrosine kinase
FLOT1 flotillin 1
G0S2 G0/G1 switch 2
GPRC5C G protein-coupled receptor, class C, group 5, member C
HAB1 B1 for mucin
HBEGF heparin-binding EGF-like growth factor
HOXA1 homeobox A1
HOXA4 homeobox A4
HOXA5 homeobox A5
HPD 4-hydroxyphenylpyruvate dioxygenase
ICAM1 intercellular adhesion molecule 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IER3 immediate early response 3
IFI6 interferon, alpha-inducible protein 6
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
KIAA0513 KIAA0513
LAMB3 laminin, beta 3
LIF leukemia inhibitory factor
LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
MAN1A1 mannosidase, alpha, class 1A, member 1
METTL7A methyltransferase like 7A
MLXIPL MLX interacting protein-like
MX2 MX dynamin-like GTPase 2
MYBPH myosin binding protein H
NCF1C neutrophil cytosolic factor 1C pseudogene
NINJ1 ninjurin 1
NRIP1 nuclear receptor interacting protein 1
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OLAH oleoyl-ACP hydrolase
PALLD palladin, cytoskeletal associated protein
PDLIM5 PDZ and LIM domain 5
PLEK pleckstrin
PLIN2 perilipin 2
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
PTGES prostaglandin E synthase
RAB31 RAB31, member RAS oncogene family
RCAN1 regulator of calcineurin 1
RRBP1 ribosome binding protein 1
SAT1 spermidine/spermine N1-acetyltransferase 1
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SLA Src-like-adaptor
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SMAD3 SMAD family member 3
SMOX spermine oxidase
SOAT1 sterol O-acyltransferase 1
SRR serine racemase
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STX11 syntaxin 11
TBL2 transducin (beta)-like 2
TGM2 transglutaminase 2
TIMP1 TIMP metallopeptidase inhibitor 1
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TREM1 triggering receptor expressed on myeloid cells 1
UPB1 ureidopropionase, beta

decreased expression

Symbol Name
ADGRA3 adhesion G protein-coupled receptor A3
ADRB2 adrenoceptor beta 2, surface
ANKRD28 ankyrin repeat domain 28
ANXA3 annexin A3
ARID5B AT rich interactive domain 5B (MRF1-like)
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BAMBI BMP and activin membrane-bound inhibitor
BATF3 basic leucine zipper transcription factor, ATF-like 3
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
C22ORF29 chromosome 22 open reading frame 29
C5 complement component 5
C5AR1 complement component 5a receptor 1
C8A complement component 8, alpha polypeptide
CA11 carbonic anhydrase XI
CA2 carbonic anhydrase II
CCDC109B coiled-coil domain containing 109B
CCL27 chemokine (C-C motif) ligand 27
CD3EAP CD3e molecule, epsilon associated protein
CD9 CD9 molecule
CDK3 cyclin-dependent kinase 3
CDR2 cerebellar degeneration-related protein 2, 62kDa
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLEC2D C-type lectin domain family 2, member D
CLEC5A C-type lectin domain family 5, member A
CLEC7A C-type lectin domain family 7, member A
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
DDN dendrin
DENND5B DENN/MADD domain containing 5B
DEPTOR DEP domain containing MTOR-interacting protein
DOCK4 dedicator of cytokinesis 4
DOK3 docking protein 3
DSPP dentin sialophosphoprotein
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EYA3 EYA transcriptional coactivator and phosphatase 3
FGF23 fibroblast growth factor 23
FJX1 four jointed box 1 (Drosophila)
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNG7 guanine nucleotide binding protein (G protein), gamma 7
HAMP hepcidin antimicrobial peptide
HIST1H2AI histone cluster 1, H2ai
HIST1H2AJ histone cluster 1, H2aj
HMGA2 high mobility group AT-hook 2
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOPX HOP homeobox
HPR haptoglobin-related protein
HYAL2 hyaluronoglucosaminidase 2
IL12RB1 interleukin 12 receptor, beta 1
IL1R2 interleukin 1 receptor, type II
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
IRX5 iroquois homeobox 5
ISOC1 isochorismatase domain containing 1
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KIAA1456 KIAA1456
KLF11 Kruppel-like factor 11
L2HGDH L-2-hydroxyglutarate dehydrogenase
LAX1 lymphocyte transmembrane adaptor 1
LIME1 Lck interacting transmembrane adaptor 1
LIN7B lin-7 homolog B (C. elegans)
LRRC20 leucine rich repeat containing 20
LY6D lymphocyte antigen 6 complex, locus D
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MMP9 matrix metallopeptidase 9
MRPS18C mitochondrial ribosomal protein S18C
MTSS1L metastasis suppressor 1-like
OCLN occludin
PIAS3 protein inhibitor of activated STAT, 3
PKD2L2 polycystic kidney disease 2-like 2
PLA2G1B phospholipase A2, group IB (pancreas)
PLCB4 phospholipase C, beta 4
PLEC plectin
POLL polymerase (DNA directed), lambda
PTX3 pentraxin 3, long
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RAD54L2 RAD54-like 2 (S. cerevisiae)
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SIDT1 SID1 transmembrane family, member 1
SLC10A3 solute carrier family 10, member 3
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SMR3A submaxillary gland androgen regulated protein 3A
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SYTL2 synaptotagmin-like 2
TEP1 telomerase-associated protein 1
THEM6 thioesterase superfamily member 6
TIGD6 tigger transposable element derived 6
TM6SF1 transmembrane 6 superfamily member 1
TMEM120B transmembrane protein 120B
TMEM134 transmembrane protein 134
TMEM212 transmembrane protein 212
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
USP32 ubiquitin specific peptidase 32
VNN2 vanin 2
WDR33 WD repeat domain 33
XAF1 XIAP associated factor 1
ZNF696 zinc finger protein 696