tremorine-6273 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the tremorine-6273 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGFG2 ArfGAP with FG repeats 2
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
APC adenomatous polyposis coli
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
BTF3P11 basic transcription factor 3 pseudogene 11
BTG4 B-cell translocation gene 4
CA1 carbonic anhydrase I
CABP2 calcium binding protein 2
CACFD1 calcium channel flower domain containing 1
CCDC64 coiled-coil domain containing 64
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CSE1L CSE1 chromosome segregation 1-like (yeast)
CYLD cylindromatosis (turban tumor syndrome)
DBF4B DBF4 zinc finger B
DHRS12 dehydrogenase/reductase (SDR family) member 12
DMPK dystrophia myotonica-protein kinase
DOK4 docking protein 4
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
DVL3 dishevelled segment polarity protein 3
EPB41L1 erythrocyte membrane protein band 4.1-like 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FAM134B family with sequence similarity 134, member B
FBXO40 F-box protein 40
FGF2 fibroblast growth factor 2 (basic)
FLJ11710 uncharacterized protein FLJ11710
FRMD1 FERM domain containing 1
FRMD4B FERM domain containing 4B
FYB FYN binding protein
GATA4 GATA binding protein 4
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GRM1 glutamate receptor, metabotropic 1
GSTCD glutathione S-transferase, C-terminal domain containing
HIC2 hypermethylated in cancer 2
ICAM1 intercellular adhesion molecule 1
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
ITPKB inositol-trisphosphate 3-kinase B
JAK3 Janus kinase 3
KIAA0754 KIAA0754
KLHL28 kelch-like family member 28
KRT13 keratin 13, type I
LEF1 lymphoid enhancer-binding factor 1
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LRRC8B leucine rich repeat containing 8 family, member B
MAP4 microtubule-associated protein 4
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MBD2 methyl-CpG binding domain protein 2
MBNL2 muscleblind-like splicing regulator 2
MECR mitochondrial trans-2-enoyl-CoA reductase
METTL7A methyltransferase like 7A
MST1 macrophage stimulating 1
MXD3 MAX dimerization protein 3
MXD4 MAX dimerization protein 4
NAAA N-acylethanolamine acid amidase
NADK NAD kinase
NCDN neurochondrin
NF1 neurofibromin 1
NFE2L3 nuclear factor, erythroid 2-like 3
NIPAL2 NIPA-like domain containing 2
ONECUT2 one cut homeobox 2
PAX5 paired box 5
PBX2 pre-B-cell leukemia homeobox 2
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDE4DIP phosphodiesterase 4D interacting protein
PDLIM5 PDZ and LIM domain 5
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PLSCR3 phospholipid scramblase 3
PLXNA3 plexin A3
POFUT1 protein O-fucosyltransferase 1
PRICKLE3 prickle homolog 3 (Drosophila)
PTK6 protein tyrosine kinase 6
PTMS parathymosin
PTPN1 protein tyrosine phosphatase, non-receptor type 1
QKI QKI, KH domain containing, RNA binding
RAD50 RAD50 homolog (S. cerevisiae)
RAD51B RAD51 paralog B
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
SLC12A8 solute carrier family 12, member 8
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SOSTDC1 sclerostin domain containing 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TADA3 transcriptional adaptor 3
TAT tyrosine aminotransferase
TBX6 T-box 6
TLDC1 TBC/LysM-associated domain containing 1
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WFDC2 WAP four-disulfide core domain 2
WIZ widely interspaced zinc finger motifs
ZBTB48 zinc finger and BTB domain containing 48
ZC3H7B zinc finger CCCH-type containing 7B
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF254 zinc finger protein 254
ZNF589 zinc finger protein 589
ZSCAN12 zinc finger and SCAN domain containing 12

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
AMDHD2 amidohydrolase domain containing 2
ARMC6 armadillo repeat containing 6
BAK1 BCL2-antagonist/killer 1
CBR3 carbonyl reductase 3
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC85C coiled-coil domain containing 85C
CCDC88C coiled-coil domain containing 88C
CDC37 cell division cycle 37
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
COL4A5 collagen, type IV, alpha 5
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DGKD diacylglycerol kinase, delta 130kDa
DNMBP dynamin binding protein
EDC4 enhancer of mRNA decapping 4
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
EIF5A2 eukaryotic translation initiation factor 5A2
ELOVL4 ELOVL fatty acid elongase 4
EPB41L5 erythrocyte membrane protein band 4.1 like 5
FAM114A1 family with sequence similarity 114, member A1
FAM63A family with sequence similarity 63, member A
FANCF Fanconi anemia, complementation group F
FBXL2 F-box and leucine-rich repeat protein 2
FGGY FGGY carbohydrate kinase domain containing
FLJ10038 uncharacterized protein FLJ10038
FLT4 fms-related tyrosine kinase 4
FOCAD focadhesin
FOSL1 FOS-like antigen 1
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GADD45G growth arrest and DNA-damage-inducible, gamma
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GLCE glucuronic acid epimerase
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H2AM histone cluster 1, H2am
HIST1H2BC histone cluster 1, H2bc
HOOK1 hook microtubule-tethering protein 1
HPSE heparanase
IER3IP1 immediate early response 3 interacting protein 1
IFT81 intraflagellar transport 81
KDM5C lysine (K)-specific demethylase 5C
KPTN kaptin (actin binding protein)
LAMB3 laminin, beta 3
LIN7B lin-7 homolog B (C. elegans)
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRP3 low density lipoprotein receptor-related protein 3
LRRC8E leucine rich repeat containing 8 family, member E
LY6G5C lymphocyte antigen 6 complex, locus G5C
LYRM9 LYR motif containing 9
MAGEH1 melanoma antigen family H1
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MTRF1 mitochondrial translational release factor 1
NDE1 nudE neurodevelopment protein 1
NECAB3 N-terminal EF-hand calcium binding protein 3
NHLRC2 NHL repeat containing 2
NME6 NME/NM23 nucleoside diphosphate kinase 6
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PCOLCE2 procollagen C-endopeptidase enhancer 2
PDZRN3 PDZ domain containing ring finger 3
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PTDSS2 phosphatidylserine synthase 2
RABL3 RAB, member of RAS oncogene family-like 3
RANGRF RAN guanine nucleotide release factor
RAP1GAP2 RAP1 GTPase activating protein 2
RBM42 RNA binding motif protein 42
RFTN1 raftlin, lipid raft linker 1
RGS17 regulator of G-protein signaling 17
RGS19 regulator of G-protein signaling 19
RINT1 RAD50 interactor 1
RNF126P1 ring finger protein 126 pseudogene 1
RPRD2 regulation of nuclear pre-mRNA domain containing 2
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SAMHD1 SAM domain and HD domain 1
SECTM1 secreted and transmembrane 1
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SH2D4A SH2 domain containing 4A
SLC41A3 solute carrier family 41, member 3
SOBP sine oculis binding protein homolog (Drosophila)
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TCTA T-cell leukemia translocation altered
TDRD1 tudor domain containing 1
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TSPYL2 TSPY-like 2
TULP4 tubby like protein 4
ULBP2 UL16 binding protein 2
WLS wntless Wnt ligand secretion mediator
ZBTB25 zinc finger and BTB domain containing 25
ZMYM1 zinc finger, MYM-type 1
ZNF654 zinc finger protein 654
ZNF668 zinc finger protein 668
ZNF747 zinc finger protein 747
ZNF770 zinc finger protein 770