tooth enamel Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description The hard, calcareous substance covering the exposed portion of a tooth. (BRENDA Tissue and Enzyme Source Ontology, BTO_0001844)
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Genes

283 proteins co-occuring with the tissue tooth enamel in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
AMELX amelogenin, X-linked 4.37468
AMELY amelogenin, Y-linked 4.28353
ENAM enamelin 3.28292
AMBN ameloblastin (enamel matrix protein) 3.12295
MMP20 matrix metallopeptidase 20 3.05645
CNOT8 CCR4-NOT transcription complex, subunit 8 2.74726
KLK4 kallikrein-related peptidase 4 2.5223
TUFT1 tuftelin 1 2.44385
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 2.31573
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 2.31352
STATH statherin 2.12033
AMTN amelotin 2.06103
CSN1S1 casein alpha s1 2.01772
MMP25 matrix metallopeptidase 25 1.86926
HEBP1 heme binding protein 1 1.7758
DSPP dentin sialophosphoprotein 1.77027
FAM83H family with sequence similarity 83, member H 1.75374
MMD monocyte to macrophage differentiation-associated 1.68952
GPI glucose-6-phosphate isomerase 1.64206
FAM20A family with sequence similarity 20, member A 1.59127
ODAM odontogenic, ameloblast asssociated 1.52045
WDR72 WD repeat domain 72 1.50339
MGAM maltase-glucoamylase 1.49679
IBSP integrin-binding sialoprotein 1.42229
HTN1 histatin 1 1.37088
DLX3 distal-less homeobox 3 1.36131
KAT2B K(lysine) acetyltransferase 2B 1.34496
OPN3 opsin 3 1.33727
SPP1 secreted phosphoprotein 1 1.33545
MSX2 msh homeobox 2 1.32867
BGLAP bone gamma-carboxyglutamate (gla) protein 1.30973
SHH sonic hedgehog 1.2662
ALPL alkaline phosphatase, liver/bone/kidney 1.2345
MCM8 minichromosome maintenance complex component 8 1.23004
ALPPL2 alkaline phosphatase, placental-like 2 1.22737
ALPP alkaline phosphatase, placental 1.22559
ROGDI rogdi homolog (Drosophila) 1.19534
C4ORF26 chromosome 4 open reading frame 26 1.18423
BMP4 bone morphogenetic protein 4 1.16072
KCP kielin/chordin-like protein 1.14742
FGF4 fibroblast growth factor 4 1.14387
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.13058
WDR20 WD repeat domain 20 1.12438
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 1.11553
SOSTDC1 sclerostin domain containing 1 1.06956
EMD emerin 1.06735
PHF20 PHD finger protein 20 1.06426
DEDD death effector domain containing 1.05413
KRT14 keratin 14, type I 1.0484
HACD1 3-hydroxyacyl-CoA dehydratase 1 1.04225
SPARCL1 SPARC-like 1 (hevin) 1.04181
MSX1 msh homeobox 1 1.03961
CST4 cystatin S 1.03171
SHKBP1 SH3KBP1 binding protein 1 1.01768
ARHGAP6 Rho GTPase activating protein 6 1.01725
ALB albumin 1.01637
RUNX2 runt-related transcription factor 2 1.00719
FGF7 fibroblast growth factor 7 0.953409
CEMP1 cementum protein 1 0.943505
ANGPTL6 angiopoietin-like 6 0.933195
BMP2 bone morphogenetic protein 2 0.910093
CA10 carbonic anhydrase X 0.900721
NOTCH1 notch 1 0.896045
SLC24A4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 0.894346
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 0.88671
IRF6 interferon regulatory factor 6 0.872327
FAM20C family with sequence similarity 20, member C 0.860521
LYZ lysozyme 0.858837
PRPF3 pre-mRNA processing factor 3 0.858416
ERG v-ets avian erythroblastosis virus E26 oncogene homolog 0.856312
ABR active BCR-related 0.85547
BGN biglycan 0.849165
CA6 carbonic anhydrase VI 0.844545
SLC4A2 solute carrier family 4 (anion exchanger), member 2 0.838252
ITGB6 integrin, beta 6 0.833642
MAEA macrophage erythroblast attacher 0.819412
WDR7 WD repeat domain 7 0.816486
LUM lumican 0.815233
GALNS galactosamine (N-acetyl)-6-sulfatase 0.811891
AMY1C amylase, alpha 1C (salivary) 0.801876
AMY1B amylase, alpha 1B (salivary) 0.801876
AMY1A amylase, alpha 1A (salivary) 0.800626
TGFB1 transforming growth factor, beta 1 0.795208
EXD2 exonuclease 3'-5' domain containing 2 0.791044
MTF1 metal-regulatory transcription factor 1 0.771514
FGF10 fibroblast growth factor 10 0.763226
FGF11 fibroblast growth factor 11 0.7595
ATP6V0D2 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 0.739678
GFER growth factor, augmenter of liver regeneration 0.7335
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 0.721577
GJA1 gap junction protein, alpha 1, 43kDa 0.71542
MGP matrix Gla protein 0.713779
SP6 Sp6 transcription factor 0.701489
NOVA2 neuro-oncological ventral antigen 2 0.698216
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.694128
LAMP1 lysosomal-associated membrane protein 1 0.663555
ACPP acid phosphatase, prostate 0.655024
CA2 carbonic anhydrase II 0.654212
LAMB3 laminin, beta 3 0.651777
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 0.645695
ERP29 endoplasmic reticulum protein 29 0.639619
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.62385
SYNC syncoilin, intermediate filament protein 0.622639
PHB2 prohibitin 2 0.599273
COL17A1 collagen, type XVII, alpha 1 0.595255
AGA aspartylglucosaminidase 0.590036
NOG noggin 0.578416
PTH parathyroid hormone 0.562441
APEH acylaminoacyl-peptide hydrolase 0.556467
ERCC8 excision repair cross-complementation group 8 0.55607
FGF14 fibroblast growth factor 14 0.554876
FAM46A family with sequence similarity 46, member A 0.55408
ZNF763 zinc finger protein 763 0.553286
ZNF629 zinc finger protein 629 0.553286
ZNF501 zinc finger protein 501 0.553286
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.550106
ZNF569 zinc finger protein 569 0.550106
LEF1 lymphoid enhancer-binding factor 1 0.545342
PITX2 paired-like homeodomain 2 0.543756
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) 0.543756
FGF3 fibroblast growth factor 3 0.540981
ZNF44 zinc finger protein 44 0.536229
SET SET nuclear proto-oncogene 0.531879
CA3 carbonic anhydrase III 0.531879
WNT10B wingless-type MMTV integration site family, member 10B 0.529508
CD63 CD63 molecule 0.521617
COL1A1 collagen, type I, alpha 1 0.521617
ZNF436 zinc finger protein 436 0.512957
BCL6B B-cell CLL/lymphoma 6, member B 0.510992
MNX1 motor neuron and pancreas homeobox 1 0.50942
S100A8 S100 calcium binding protein A8 0.505887
WNT6 wingless-type MMTV integration site family, member 6 0.501574
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.501182
DCN decorin 0.499223
FGF1 fibroblast growth factor 1 (acidic) 0.497266
AHSG alpha-2-HS-glycoprotein 0.495309
KRT24 keratin 24, type I 0.491009
WARS tryptophanyl-tRNA synthetase 0.489057
ASPA aspartoacylase 0.479702
COLEC12 collectin sub-family member 12 0.478145
DES desmin 0.473869
FN1 fibronectin 1 0.47348
PTCH1 patched 1 0.472315
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 0.471927
ZNF92 zinc finger protein 92 0.469987
SKP1 S-phase kinase-associated protein 1 0.469211
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 0.468048
SPPL2A signal peptide peptidase like 2A 0.466885
SP7 Sp7 transcription factor 0.4634
SLC35B4 solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4 0.456828
CLNK cytokine-dependent hematopoietic cell linker 0.455284
SPRY4 sprouty homolog 4 (Drosophila) 0.453355
HAND1 heart and neural crest derivatives expressed 1 0.451428
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like 0.451428
TFIP11 tuftelin interacting protein 11 0.442962
CALB1 calbindin 1, 28kDa 0.439123
LHX8 LIM homeobox 8 0.438356
CLCN7 chloride channel, voltage-sensitive 7 0.435672
AXIN2 axin 2 0.43414
PART1 prostate androgen-regulated transcript 1 (non-protein coding) 0.433374
BMP6 bone morphogenetic protein 6 0.432225
RPL21 ribosomal protein L21 0.428783
PERP PERP, TP53 apoptosis effector 0.422292
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7 0.420385
NIPBL Nipped-B homolog (Drosophila) 0.416576
AIRE autoimmune regulator 0.410491
HRAS Harvey rat sarcoma viral oncogene homolog 0.410491
PITRM1 pitrilysin metallopeptidase 1 0.407832
YIPF4 Yip1 domain family, member 4 0.406315
APLP1 amyloid beta (A4) precursor-like protein 1 0.397979
CLSTN1 calsyntenin 1 0.396844
BMP7 bone morphogenetic protein 7 0.390799
PLXNB3 plexin B3 0.38552
SMAD1 SMAD family member 1 0.377996
PSMG3 proteasome (prosome, macropain) assembly chaperone 3 0.377621
DACT3 dishevelled-binding antagonist of beta-catenin 3 0.376119
ZKSCAN7 zinc finger with KRAB and SCAN domains 7 0.374993
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 0.374993
MMP2 matrix metallopeptidase 2 0.372743
LTF lactotransferrin 0.370121
PTCH2 patched 2 0.366381
DMBT1 deleted in malignant brain tumors 1 0.365633
FST follistatin 0.364139
APLF aprataxin and PNKP like factor 0.361901
PER2 period circadian clock 2 0.361155
ITGB8 integrin, beta 8 0.360782
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.360036
PSG1 pregnancy specific beta-1-glycoprotein 1 0.359292
PRB2 proline-rich protein BstNI subfamily 2 0.357802
PARP14 poly (ADP-ribose) polymerase family, member 14 0.35743
FGF17 fibroblast growth factor 17 0.354455
FXYD1 FXYD domain containing ion transport regulator 1 0.352227
VCAN versican 0.351485
EVC2 Ellis van Creveld syndrome 2 0.350001
DSP desmoplakin 0.341495
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 0.341495
LPO lactoperoxidase 0.341126
ITGA6 integrin, alpha 6 0.33965
WLS wntless Wnt ligand secretion mediator 0.33965
RHOQ ras homolog family member Q 0.337808
DACT2 dishevelled-binding antagonist of beta-catenin 2 0.337072
ITGB7 integrin, beta 7 0.334498
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 0.328994
DNAH8 dynein, axonemal, heavy chain 8 0.326067
CDKN2A cyclin-dependent kinase inhibitor 2A 0.321685
KLK5 kallikrein-related peptidase 5 0.320227
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 0.319863
TFDP3 transcription factor Dp family, member 3 0.319863
PCNA proliferating cell nuclear antigen 0.317315
FGF16 fibroblast growth factor 16 0.31332
FGF12 fibroblast growth factor 12 0.308974
IGF1 insulin-like growth factor 1 (somatomedin C) 0.308612
ITM2A integral membrane protein 2A 0.308251
GP2 glycoprotein 2 (zymogen granule membrane) 0.305722
CLCN5 chloride channel, voltage-sensitive 5 0.30464
C3ORF18 chromosome 3 open reading frame 18 0.303559
COL7A1 collagen, type VII, alpha 1 0.302118
CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 0.298883
DPYSL4 dihydropyrimidinase-like 4 0.297447
EXOSC8 exosome component 8 0.296372
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 0.296013
TRPV3 transient receptor potential cation channel, subfamily V, member 3 0.293151
RAB23 RAB23, member RAS oncogene family 0.290652
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 0.289582
SETD2 SET domain containing 2 0.289226
ATE1 arginyltransferase 1 0.288158
DMP1 dentin matrix acidic phosphoprotein 1 0.286026
ASPN asporin 0.280717
KDM2B lysine (K)-specific demethylase 2B 0.280717
SLC35E2B solute carrier family 35, member E2B 0.278251
OMD osteomodulin 0.273696
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa 0.273346
MAGEA6 melanoma antigen family A6 0.271604
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 0.269521
COL1A2 collagen, type I, alpha 2 0.269174
DERA deoxyribose-phosphate aldolase (putative) 0.268828
ASB2 ankyrin repeat and SOCS box containing 2 0.267446
COPB2 coatomer protein complex, subunit beta 2 (beta prime) 0.265381
DLX5 distal-less homeobox 5 0.264696
BARX2 BARX homeobox 2 0.264353
STPG1 sperm-tail PG-rich repeat containing 1 0.264353
DDB1 damage-specific DNA binding protein 1, 127kDa 0.262304
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 0.261964
TUBA1B tubulin, alpha 1b 0.259254
EPHA4 EPH receptor A4 0.257907
TIMP2 TIMP metallopeptidase inhibitor 2 0.257907
C1ORF174 chromosome 1 open reading frame 174 0.257572
EDARADD EDAR-associated death domain 0.256568
MEPE matrix extracellular phosphoglycoprotein 0.254902
TAAR8 trace amine associated receptor 8 0.254902
ITGB4 integrin, beta 4 0.254902
SV2C synaptic vesicle glycoprotein 2C 0.254902
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) 0.253908
CST2 cystatin SA 0.252919
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.249329
WNT10A wingless-type MMTV integration site family, member 10A 0.244545
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.243918
PLXNC1 plexin C1 0.242672
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.242672
FGF2 fibroblast growth factor 2 (basic) 0.238706
FGFR2 fibroblast growth factor receptor 2 0.238108
NT5M 5',3'-nucleotidase, mitochondrial 0.232039
TNC tenascin C 0.231482
CTNNBIP1 catenin, beta interacting protein 1 0.230382
CLDN1 claudin 1 0.230382
AGK acylglycerol kinase 0.230382
ITSN1 intersectin 1 (SH3 domain protein) 0.23011
SETD1A SET domain containing 1A 0.228764
PLXNB2 plexin B2 0.22797
FBXO2 F-box protein 2 0.22797
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha 0.227186
CLDN7 claudin 7 0.2259
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.225144
PAX9 paired box 9 0.224645
CLDN4 claudin 4 0.222938
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) 0.222224
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 0.221061
BMP3 bone morphogenetic protein 3 0.219928
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.219264
TSPO translocator protein (18kDa) 0.218398
DACT1 dishevelled-binding antagonist of beta-catenin 1 0.218186
GLI1 GLI family zinc finger 1 0.213471
NOTCH2 notch 2 0.212586