tolerance Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

334 genes co-occuring with the biological term tolerance in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACE angiotensin I converting enzyme
ADA adenosine deaminase
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
ADIPOQ adiponectin, C1Q and collagen domain containing
ADORA2B adenosine A2b receptor
ADRB1 adrenoceptor beta 1
ADRB2 adrenoceptor beta 2, surface
ADRB3 adrenoceptor beta 3
AHSG alpha-2-HS-glycoprotein
AIRE autoimmune regulator
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ANGPT2 angiopoietin 2
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
ARF6 ADP-ribosylation factor 6
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARSA arylsulfatase A
AS3MT arsenite methyltransferase
ATF3 activating transcription factor 3
ATF7IP activating transcription factor 7 interacting protein
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCL3 B-cell CLL/lymphoma 3
BECN1 beclin 1, autophagy related
BGLAP bone gamma-carboxyglutamate (gla) protein
BIRC5 baculoviral IAP repeat containing 5
BMP7 bone morphogenetic protein 7
BPI bactericidal/permeability-increasing protein
BTK Bruton agammaglobulinemia tyrosine kinase
C1QTNF3 C1q and tumor necrosis factor related protein 3
C3 complement component 3
CAMP cathelicidin antimicrobial peptide
CAPN10 calpain 10
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CBX5 chromobox homolog 5
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCL2 chemokine (C-C motif) ligand 2
CCL24 chemokine (C-C motif) ligand 24
CCL28 chemokine (C-C motif) ligand 28
CCL5 chemokine (C-C motif) ligand 5
CCR2 chemokine (C-C motif) receptor 2
CD14 CD14 molecule
CD19 CD19 molecule
CD209 CD209 molecule
CD27 CD27 molecule
CD274 CD274 molecule
CD28 CD28 molecule
CD34 CD34 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD4 CD4 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD70 CD70 molecule
CD80 CD80 molecule
CD83 CD83 molecule
CD86 CD86 molecule
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CETP cholesteryl ester transfer protein, plasma
CGB chorionic gonadotropin, beta polypeptide
CHGA chromogranin A
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHIT1 chitinase 1 (chitotriosidase)
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CHUK conserved helix-loop-helix ubiquitous kinase
CLEC4C C-type lectin domain family 4, member C
CLEC4M C-type lectin domain family 4, member M
CLEC7A C-type lectin domain family 7, member A
CLSPN claspin
CNR1 cannabinoid receptor 1 (brain)
COL2A1 collagen, type II, alpha 1
CPT1A carnitine palmitoyltransferase 1A (liver)
CREBZF CREB/ATF bZIP transcription factor
CRP C-reactive protein, pentraxin-related
CTF1 cardiotrophin 1
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTSB cathepsin B
CTSL cathepsin L
CXCL12 chemokine (C-X-C motif) ligand 12
CXCR4 chemokine (C-X-C motif) receptor 4
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DEFB4A defensin, beta 4A
DLAT dihydrolipoamide S-acetyltransferase
DOCK8 dedicator of cytokinesis 8
DOK3 docking protein 3
DRD3 dopamine receptor D3
DUSP1 dual specificity phosphatase 1
DUSP5 dual specificity phosphatase 5
DYNLT1 dynein, light chain, Tctex-type 1
EBAG9 estrogen receptor binding site associated, antigen, 9
EGFR epidermal growth factor receptor
EHMT2 euchromatic histone-lysine N-methyltransferase 2
ENHO energy homeostasis associated
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
ERLEC1 endoplasmic reticulum lectin 1
F5 coagulation factor V (proaccelerin, labile factor)
F8 coagulation factor VIII, procoagulant component
FABP4 fatty acid binding protein 4, adipocyte
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FCRL3 Fc receptor-like 3
FOXO1 forkhead box O1
FOXP3 forkhead box P3
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GAL galanin/GMAP prepropeptide
GAS6 growth arrest-specific 6
GATA3 GATA binding protein 3
GCG glucagon
GCK glucokinase (hexokinase 4)
GH1 growth hormone 1
GHRL ghrelin/obestatin prepropeptide
GIPR gastric inhibitory polypeptide receptor
GJB2 gap junction protein, beta 2, 26kDa
GRN granulin
GSK3B glycogen synthase kinase 3 beta
HAVCR1 hepatitis A virus cellular receptor 1
HBA1 hemoglobin, alpha 1
HCST hematopoietic cell signal transducer
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-C major histocompatibility complex, class I, C
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB5 major histocompatibility complex, class II, DR beta 5
HLA-G major histocompatibility complex, class I, G
HSF1 heat shock transcription factor 1
HSPA1A heat shock 70kDa protein 1A
HSPB1 heat shock 27kDa protein 1
ICOS inducible T-cell co-stimulator
IDO1 indoleamine 2,3-dioxygenase 1
IDO2 indoleamine 2,3-dioxygenase 2
IFNA1 interferon, alpha 1
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGF2 insulin-like growth factor 2
IGFBP1 insulin-like growth factor binding protein 1
IGFBP3 insulin-like growth factor binding protein 3
IL10 interleukin 10
IL13 interleukin 13
IL15 interleukin 15
IL15RA interleukin 15 receptor, alpha
IL1B interleukin 1, beta
IL2 interleukin 2
IL22 interleukin 22
IL2RA interleukin 2 receptor, alpha
IL4 interleukin 4
IL5 interleukin 5
IL6 interleukin 6
IL6R interleukin 6 receptor
IL7 interleukin 7
INO80 INO80 complex subunit
INS insulin
IRAK1 interleukin-1 receptor-associated kinase 1
IRAK3 interleukin-1 receptor-associated kinase 3
IRAK4 interleukin-1 receptor-associated kinase 4
IRF4 interferon regulatory factor 4
IRG1 immunoresponsive 1 homolog (mouse)
IRS1 insulin receptor substrate 1
ITCH itchy E3 ubiquitin protein ligase
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB6 integrin, beta 6
ITLN1 intelectin 1 (galactofuranose binding)
JUN jun proto-oncogene
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KLRK1 killer cell lectin-like receptor subfamily K, member 1
LCT lactase
LEP leptin
LEPR leptin receptor
LGALS3 lectin, galactoside-binding, soluble, 3
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LPL lipoprotein lipase
MAOA monoamine oxidase A
MBD1 methyl-CpG binding domain protein 1
MBP myelin basic protein
MGAM maltase-glucoamylase
MIR146A microRNA 146a
MIR150 microRNA 150
MIR155 microRNA 155
MPZ myelin protein zero
MST1 macrophage stimulating 1
MTMR9 myotubularin related protein 9
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MTTP microsomal triglyceride transfer protein
MUC16 mucin 16, cell surface associated
NAMPT nicotinamide phosphoribosyltransferase
NEU3 sialidase 3 (membrane sialidase)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NOD2 nucleotide-binding oligomerization domain containing 2
NOS3 nitric oxide synthase 3 (endothelial cell)
NPPA natriuretic peptide A
NPPB natriuretic peptide B
NPY neuropeptide Y
NRP1 neuropilin 1
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae)
NT5E 5'-nucleotidase, ecto (CD73)
NUCB2 nucleobindin 2
OGG1 8-oxoguanine DNA glycosylase
OPRD1 opioid receptor, delta 1
OPRK1 opioid receptor, kappa 1
OPRM1 opioid receptor, mu 1
PAH phenylalanine hydroxylase
PARD6A par-6 family cell polarity regulator alpha
PARP1 poly (ADP-ribose) polymerase 1
PARVG parvin, gamma
PAX4 paired box 4
PAX6 paired box 6
PCNA proliferating cell nuclear antigen
PDCD1 programmed cell death 1
PEA15 phosphoprotein enriched in astrocytes 15
PER2 period circadian clock 2
PHB prohibitin
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLAT plasminogen activator, tissue
PLD2 phospholipase D2
POLH polymerase (DNA directed), eta
PON1 paraoxonase 1
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PRAME preferentially expressed antigen in melanoma
PRDM1 PR domain containing 1, with ZNF domain
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PRTN3 proteinase 3
PSG2 pregnancy specific beta-1-glycoprotein 2
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RAD17 RAD17 homolog (S. pombe)
RAD51 RAD51 recombinase
RAD9A RAD9 homolog A (S. pombe)
RAG2 recombination activating gene 2
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RBP4 retinol binding protein 4, plasma
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RETN resistin
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SECTM1 secreted and transmembrane 1
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SFRP4 secreted frizzled-related protein 4
SFTPA1 surfactant protein A1
SFTPC surfactant protein C
SH2D1A SH2 domain containing 1A
SHBG sex hormone-binding globulin
SIRPA signal-regulatory protein alpha
SIRT1 sirtuin 1
SIT1 signaling threshold regulating transmembrane adaptor 1
SIVA1 SIVA1, apoptosis-inducing factor
SLAMF1 signaling lymphocytic activation molecule family member 1
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC44A4 solute carrier family 44, member 4
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SMAD4 SMAD family member 4
SOD2 superoxide dismutase 2, mitochondrial
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5B signal transducer and activator of transcription 5B
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STEAP1 six transmembrane epithelial antigen of the prostate 1
STK25 serine/threonine kinase 25
TARDBP TAR DNA binding protein
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TERF1 telomeric repeat binding factor (NIMA-interacting) 1
TERF2 telomeric repeat binding factor 2
TERT telomerase reverse transcriptase
TFRC transferrin receptor
TGFB1 transforming growth factor, beta 1
TGFB3 transforming growth factor, beta 3
TH tyrosine hydroxylase
TIMD4 T-cell immunoglobulin and mucin domain containing 4
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TLR7 toll-like receptor 7
TLR8 toll-like receptor 8
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNNI3 troponin I type 3 (cardiac)
TOPBP1 topoisomerase (DNA) II binding protein 1
TPH1 tryptophan hydroxylase 1
TPO thyroid peroxidase
TRA T cell receptor alpha locus
TRAF2 TNF receptor-associated factor 2
TRD T cell receptor delta locus
TREM1 triggering receptor expressed on myeloid cells 1
TRG T cell receptor gamma locus
TRIB3 tribbles pseudokinase 3
TRIM21 tripartite motif containing 21
TROVE2 TROVE domain family, member 2
TRPM6 transient receptor potential cation channel, subfamily M, member 6
TSHR thyroid stimulating hormone receptor
TSLP thymic stromal lymphopoietin
TYROBP TYRO protein tyrosine kinase binding protein
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
ULK1 unc-51 like autophagy activating kinase 1
VASH1 vasohibin 1
VEGFA vascular endothelial growth factor A
VWF von Willebrand factor
WT1 Wilms tumor 1
ZBTB7A zinc finger and BTB domain containing 7A
ZC3H12A zinc finger CCCH-type containing 12A