thyroid medullary carcinoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A follicular thyroid carcinoma that has_material_basis_in parafollicular cells. (Human Disease Ontology, DOID_3973)
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Genes

122 genes co-occuring with the disease thyroid medullary carcinoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
RET ret proto-oncogene 3.43534
CALCA calcitonin-related polypeptide alpha 3.41191
SST somatostatin 1.81013
CHGA chromogranin A 1.48077
TG thyroglobulin 1.42981
CALCB calcitonin-related polypeptide beta 1.39302
MEN1 multiple endocrine neoplasia I 1.21522
SSTR2 somatostatin receptor 2 1.15283
POMC proopiomelanocortin 1.15027
GFRA1 GDNF family receptor alpha 1 1.07488
ENO2 enolase 2 (gamma, neuronal) 1.02397
GDNF glial cell derived neurotrophic factor 1.01469
PSPN persephin 1.00963
GRP gastrin-releasing peptide 0.988957
GAST gastrin 0.949102
SSTR5 somatostatin receptor 5 0.920085
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.911845
PTH parathyroid hormone 0.882701
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 0.864684
SYP synaptophysin 0.836017
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 0.828229
SSTR1 somatostatin receptor 1 0.805257
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4 0.795002
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa 0.752085
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 0.736649
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 0.703134
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5 0.701928
ZNF22 zinc finger protein 22 0.677903
GFRA3 GDNF family receptor alpha 3 0.669538
ARTN artemin 0.664769
CCKBR cholecystokinin B receptor 0.641827
NRTN neurturin 0.63907
NTS neurotensin 0.626888
SYT5 synaptotagmin V 0.619834
GOLGA3 golgin A3 0.619051
CCK cholecystokinin 0.604591
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast) 0.580828
NKX2-1 NK2 homeobox 1 0.569941
HRAS Harvey rat sarcoma viral oncogene homolog 0.56722
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 0.565666
ADAP1 ArfGAP with dual PH domains 1 0.555568
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) 0.55518
MIR183 microRNA 183 0.554403
GCG glucagon 0.545481
CRH corticotropin releasing hormone 0.529222
PAM peptidylglycine alpha-amidating monooxygenase 0.528063
SLC16A6 solute carrier family 16, member 6 0.526518
CHGB chromogranin B 0.52536
SPATA19 spermatogenesis associated 19 0.504973
SMS spermine synthase 0.503058
GFRA2 GDNF family receptor alpha 2 0.501527
RPIA ribose 5-phosphate isomerase A 0.501527
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast) 0.483604
RASSF7 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 0.474119
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 0.465416
COX4I2 cytochrome c oxidase subunit IV isoform 2 (lung) 0.454093
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae) 0.446935
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7 0.446182
MIR10A microRNA 10a 0.446182
NF1 neurofibromin 1 0.43753
MLNR motilin receptor 0.436026
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 0.431519
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1 0.42589
TAC1 tachykinin, precursor 1 0.401945
PTEN phosphatase and tensin homolog 0.386679
UBN1 ubinuclein 1 0.385193
LGALS3 lectin, galactoside-binding, soluble, 3 0.38111
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta 0.377773
TNS1 tensin 1 0.36704
SCG2 secretogranin II 0.364085
CASR calcium-sensing receptor 0.35892
SSTR4 somatostatin receptor 4 0.357814
TP53 tumor protein p53 0.355235
ZNF135 zinc finger protein 135 0.351187
RNF11 ring finger protein 11 0.347511
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.340906
PAX8 paired box 8 0.338707
INTU inturned planar cell polarity protein 0.338707
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.316819
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.312464
HNRNPF heterogeneous nuclear ribonucleoprotein F 0.301615
SSTR3 somatostatin receptor 3 0.301254
SDHAF2 succinate dehydrogenase complex assembly factor 2 0.28831
C1QBP complement component 1, q subcomponent binding protein 0.282582
ZHX2 zinc fingers and homeoboxes 2 0.27687
OPTC opticin 0.276158
IAPP islet amyloid polypeptide 0.268687
LYPD1 LY6/PLAUR domain containing 1 0.267622
CALCR calcitonin receptor 0.266203
PGLS 6-phosphogluconolactonase 0.265494
VIP vasoactive intestinal peptide 0.25983
PTCH1 patched 1 0.257711
XPO5 exportin 5 0.250311
ERC1 ELKS/RAB6-interacting/CAST family member 1 0.24715
TPCN1 two pore segment channel 1 0.222479
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 0.211934
GAB1 GRB2-associated binding protein 1 0.207912
KDR kinase insert domain receptor 0.20658
FMN2 formin 2 0.200006
CDC73 cell division cycle 73 0.197099
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.187113
DKK4 dickkopf WNT signaling pathway inhibitor 4 0.182086
LCK LCK proto-oncogene, Src family tyrosine kinase 0.181222
ASCL1 achaete-scute family bHLH transcription factor 1 0.179239
UCN3 urocortin 3 0.172544
BMF Bcl2 modifying factor 0.168854
TFF1 trefoil factor 1 0.168617
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 0.165435
RAMP3 receptor (G protein-coupled) activity modifying protein 3 0.162908
ADRA1B adrenoceptor alpha 1B 0.161139
GRB2 growth factor receptor-bound protein 2 0.158778
GAGE1 G antigen 1 0.158266
NGF nerve growth factor (beta polypeptide) 0.157929
IL2 interleukin 2 0.157602
FRS2 fibroblast growth factor receptor substrate 2 0.145496
YARS tyrosyl-tRNA synthetase 0.144598
CSF1 colony stimulating factor 1 (macrophage) 0.143436
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase 0.143049
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.141971
CX3CL1 chemokine (C-X3-C motif) ligand 1 0.141607
ANOS1 anosmin 1 0.141586
MAPK9 mitogen-activated protein kinase 9 0.141438