thyroid gland disease Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
Description An endocrine system disease that is located_in the thyroid. (Human Disease Ontology, DOID_50)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:50
Similar Terms
Downloads & Tools

Genes

153 genes associated with the disease thyroid gland disease in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
PDE8B phosphodiesterase 8B 1.93135
CUBN cubilin (intrinsic factor-cobalamin receptor) 1.63837
DIO1 deiodinase, iodothyronine, type I 1.50077
TMEM196 transmembrane protein 196 1.36306
PDE10A phosphodiesterase 10A 1.30392
HSPA4L heat shock 70kDa protein 4-like 1.11647
ADAM23 ADAM metallopeptidase domain 23 1.10352
TTC21A tetratricopeptide repeat domain 21A 1.08467
HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 1.01472
FGF7 fibroblast growth factor 7 0.940142
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1 0.907073
SLC14A2 solute carrier family 14 (urea transporter), member 2 0.90019
DNAH7 dynein, axonemal, heavy chain 7 0.889009
FGD4 FYVE, RhoGEF and PH domain containing 4 0.873981
SLC35F3 solute carrier family 35, member F3 0.852303
LRRC4C leucine rich repeat containing 4C 0.839855
MED27 mediator complex subunit 27 0.804959
ZDHHC21 zinc finger, DHHC-type containing 21 0.79917
HPS1 Hermansky-Pudlak syndrome 1 0.783487
RPH3A rabphilin 3A 0.735995
SMIM23 small integral membrane protein 23 0.732866
PRKCH protein kinase C, eta 0.731451
EPAS1 endothelial PAS domain protein 1 0.724637
DLG2 discs, large homolog 2 (Drosophila) 0.711975
PHACTR1 phosphatase and actin regulator 1 0.696883
FAM110B family with sequence similarity 110, member B 0.691297
LHX3 LIM homeobox 3 0.649327
C1QTNF6 C1q and tumor necrosis factor related protein 6 0.578741
TSHR thyroid stimulating hormone receptor 0.54844
NFIA nuclear factor I/A 0.533842
C6ORF10 chromosome 6 open reading frame 10 0.510578
PRDM11 PR domain containing 11 0.485556
INSR insulin receptor 0.479419
CAPZB capping protein (actin filament) muscle Z-line, beta 0.471342
SLAMF6 SLAM family member 6 0.471183
NRG1 neuregulin 1 0.466919
GLIS3 GLIS family zinc finger 3 0.450616
HLA-J major histocompatibility complex, class I, J (pseudogene) 0.446646
LPCAT2 lysophosphatidylcholine acyltransferase 2 0.445543
TCF19 transcription factor 19 0.438494
CCHCR1 coiled-coil alpha-helical rod protein 1 0.431587
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 0.426917
MUC22 mucin 22 0.426917
FCRL3 Fc receptor-like 3 0.423308
SH2B3 SH2B adaptor protein 3 0.408185
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.406304
ATXN2 ataxin 2 0.40482
FGFR1OP FGFR1 oncogene partner 0.385768
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 0.384109
MOG myelin oligodendrocyte glycoprotein 0.378433
NAA25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit 0.374839
CEP128 centrosomal protein 128kDa 0.372205
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 0.371761
VAV3 vav 3 guanine nucleotide exchange factor 0.366175
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 0.364313
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.353629
CNTNAP2 contactin associated protein-like 2 0.353221
TG thyroglobulin 0.346184
FCRL1 Fc receptor-like 1 0.343111
MINOS1 mitochondrial inner membrane organizing system 1 0.336118
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.325497
TNF tumor necrosis factor 0.322914
NELFE negative elongation factor complex member E 0.310282
SLA Src-like-adaptor 0.302322
RNASET2 ribonuclease T2 0.291541
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor 0.285776
CD5L CD5 molecule-like 0.28513
HLA-B major histocompatibility complex, class I, B 0.284819
PTPRT protein tyrosine phosphatase, receptor type, T 0.283187
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.282366
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 0.282366
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 0.278811
C6ORF15 chromosome 6 open reading frame 15 0.275929
NCKAP5 NCK-associated protein 5 0.272636
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 0.271419
FCRL2 Fc receptor-like 2 0.26623
CFB complement factor B 0.263678
RECQL5 RecQ protein-like 5 0.263448
ASIC2 acid sensing (proton gated) ion channel 2 0.262778
ZNF804B zinc finger protein 804B 0.262778
CTLA4 cytotoxic T-lymphocyte-associated protein 4 0.262778
MTF1 metal-regulatory transcription factor 1 0.258953
HCG22 HLA complex group 22 0.258102
LOC100506999 uncharacterized LOC100506999 0.254007
TSHZ2 teashirt zinc finger homeobox 2 0.254007
INPP5B inositol polyphosphate-5-phosphatase, 75kDa 0.250132
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B 0.249018
CALD1 caldesmon 1 0.248487
PFKP phosphofructokinase, platelet 0.247974
PPP2R2C protein phosphatase 2, regulatory subunit B, gamma 0.246991
RAB20 RAB20, member RAS oncogene family 0.244353
CLECL1 C-type lectin-like 1 0.244353
CALN1 calneuron 1 0.24356
PRKCE protein kinase C, epsilon 0.242081
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A 0.240087
LACTB lactamase, beta 0.239473
ZDHHC17 zinc finger, DHHC-type containing 17 0.239473
THSD4 thrombospondin, type I, domain containing 4 0.23831
PCDH15 protocadherin-related 15 0.23831
GNG2 guanine nucleotide binding protein (G protein), gamma 2 0.235254
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.234978
VAV1 vav 1 guanine nucleotide exchange factor 0.234932
SNAP47 synaptosomal-associated protein, 47kDa 0.234796
AGER advanced glycosylation end product-specific receptor 0.233918
BTNL2 butyrophilin-like 2 0.233497
FOXE1 forkhead box E1 0.231177
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa 0.230474
FKTN fukutin 0.230133
TASP1 taspase, threonine aspartase, 1 0.228696
VTI1A vesicle transport through interaction with t-SNAREs 1A 0.227745
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.22746
RBP4 retinol binding protein 4, plasma 0.227118
VMP1 vacuole membrane protein 1 0.226813
TTLL6 tubulin tyrosine ligase-like family member 6 0.225929
TRIM15 tripartite motif containing 15 0.225644
WISP1 WNT1 inducible signaling pathway protein 1 0.225476
STAC SH3 and cysteine rich domain 0.225392
RTKN2 rhotekin 2 0.225116
ANKRD26 ankyrin repeat domain 26 0.225089
DFNB31 deafness, autosomal recessive 31 0.224393
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing 0.224029
CASC15 cancer susceptibility candidate 15 (non-protein coding) 0.224029
CLDN2 claudin 2 0.223276
IL2RA interleukin 2 receptor, alpha 0.223276
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 0.223032
KIRREL3 kin of IRRE like 3 (Drosophila) 0.223032
CHL1 cell adhesion molecule L1-like 0.222791
KLHL29 kelch-like family member 29 0.222791
DCBLD1 discoidin, CUB and LCCL domain containing 1 0.222791
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1 0.222554
URI1 URI1, prefoldin-like chaperone 0.22232
CSMD3 CUB and Sushi multiple domains 3 0.22225
OPCML opioid binding protein/cell adhesion molecule-like 0.221637
DAAM1 dishevelled associated activator of morphogenesis 1 0.220981
RIN2 Ras and Rab interactor 2 0.220874
DKK2 dickkopf WNT signaling pathway inhibitor 2 0.220557
TNNT3 troponin T type 3 (skeletal, fast) 0.220349
CNTN4 contactin 4 0.220143
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.21994
GPC5 glypican 5 0.21994
ERICH1 glutamate-rich 1 0.219152
ERCC5 excision repair cross-complementation group 5 0.218399
MACROD2 MACRO domain containing 2 0.217855
MAN1C1 mannosidase, alpha, class 1C, member 1 0.217678
KALRN kalirin, RhoGEF kinase 0.209698
RNF144A ring finger protein 144A 0.203798
HCG9 HLA complex group 9 (non-protein coding) 0.195137
CIPC CLOCK-interacting pacemaker 0.186699
ACSF3 acyl-CoA synthetase family member 3 0.18583
IRF2BPL interferon regulatory factor 2 binding protein-like 0.177947
LEMD2 LEM domain containing 2 0.177603
CLEC16A C-type lectin domain family 16, member A 0.177603
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 0.177495