thin cerebellar molecular layer Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduced width of the outermost layer of the cerebral cortex that contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells (Mammalian Phenotype Ontology, MP_0000890)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0000890
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Genes

18 gene mutations causing the thin cerebellar molecular layer phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AFF1 AF4/FMR2 family, member 1
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ATM ATM serine/threonine kinase
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CEND1 cell cycle exit and neuronal differentiation 1
COMMD3-BMI1 COMMD3-BMI1 readthrough
FOXP2 forkhead box P2
GRID2 glutamate receptor, ionotropic, delta 2
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C
KLHL1 kelch-like family member 1
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
NEUROD4 neuronal differentiation 4
PRNP prion protein
RORA RAR-related orphan receptor A
SKOR2 SKI family transcriptional corepressor 2
SPTBN2 spectrin, beta, non-erythrocytic 2
THRB thyroid hormone receptor, beta