thiethylperazine-6232 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the thiethylperazine-6232 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACOT11 acyl-CoA thioesterase 11
AK1 adenylate kinase 1
AKAP8L A kinase (PRKA) anchor protein 8-like
ALDOB aldolase B, fructose-bisphosphate
ARID1A AT rich interactive domain 1A (SWI-like)
ATM ATM serine/threonine kinase
AVL9 AVL9 homolog (S. cerevisiase)
BCL2L2 BCL2-like 2
BMP2K BMP2 inducible kinase
C11ORF80 chromosome 11 open reading frame 80
C14ORF1 chromosome 14 open reading frame 1
CACFD1 calcium channel flower domain containing 1
CALML3 calmodulin-like 3
CCNT2 cyclin T2
CD4 CD4 molecule
CDC25C cell division cycle 25C
CEP152 centrosomal protein 152kDa
CHKB choline kinase beta
CHM choroideremia (Rab escort protein 1)
DNM1 dynamin 1
DTNA dystrobrevin, alpha
ELSPBP1 epididymal sperm binding protein 1
EML3 echinoderm microtubule associated protein like 3
EPOR erythropoietin receptor
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FGFR2 fibroblast growth factor receptor 2
FKBP8 FK506 binding protein 8, 38kDa
FOSL2 FOS-like antigen 2
FYB FYN binding protein
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-G major histocompatibility complex, class I, G
HSPB6 heat shock protein, alpha-crystallin-related, B6
IDI2-AS1 IDI2 antisense RNA 1
IGFBP3 insulin-like growth factor binding protein 3
IGFBP5 insulin-like growth factor binding protein 5
IGSF1 immunoglobulin superfamily, member 1
IL23A interleukin 23, alpha subunit p19
IL6ST interleukin 6 signal transducer
IRF6 interferon regulatory factor 6
JRK Jrk homolog (mouse)
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KIAA1109 KIAA1109
LRP2 low density lipoprotein receptor-related protein 2
LRRC41 leucine rich repeat containing 41
MALT1 MALT1 paracaspase
MAP2K5 mitogen-activated protein kinase kinase 5
MATK megakaryocyte-associated tyrosine kinase
MBNL2 muscleblind-like splicing regulator 2
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MOBP myelin-associated oligodendrocyte basic protein
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
NDE1 nudE neurodevelopment protein 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NXPH4 neurexophilin 4
OSMR oncostatin M receptor
PGP phosphoglycolate phosphatase
PHLDB1 pleckstrin homology-like domain, family B, member 1
PRDX2 peroxiredoxin 2
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PTHLH parathyroid hormone-like hormone
PTK6 protein tyrosine kinase 6
RANBP3 RAN binding protein 3
RGS3 regulator of G-protein signaling 3
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF6 ring finger protein (C3H2C3 type) 6
RPL13P5 ribosomal protein L13 pseudogene 5
SCN1B sodium channel, voltage gated, type I beta subunit
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SGSM2 small G protein signaling modulator 2
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa
SNW1 SNW domain containing 1
SOX4 SRY (sex determining region Y)-box 4
SPTBN1 spectrin, beta, non-erythrocytic 1
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STRA6 stimulated by retinoic acid 6
TBX6 T-box 6
TCTA T-cell leukemia translocation altered
TGM2 transglutaminase 2
TLR2 toll-like receptor 2
TMEM63A transmembrane protein 63A
TOP3A topoisomerase (DNA) III alpha
TRD T cell receptor delta locus
UBE2D2 ubiquitin-conjugating enzyme E2D 2
USF2 upstream transcription factor 2, c-fos interacting
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZFPL1 zinc finger protein-like 1
ZNF117 zinc finger protein 117
ZNF277 zinc finger protein 277
ZNF350 zinc finger protein 350
ZNF444 zinc finger protein 444
ZNF813 zinc finger protein 813

decreased expression

Symbol Name
ACVR2B activin A receptor, type IIB
ANKRD28 ankyrin repeat domain 28
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
ARHGAP10 Rho GTPase activating protein 10
ATG4A autophagy related 4A, cysteine peptidase
ATG7 autophagy related 7
AXIN1 axin 1
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BTF3P11 basic transcription factor 3 pseudogene 11
CASZ1 castor zinc finger 1
CCDC130 coiled-coil domain containing 130
CCDC25 coiled-coil domain containing 25
CLASP1 cytoplasmic linker associated protein 1
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CPPED1 calcineurin-like phosphoesterase domain containing 1
CTSV cathepsin V
CXORF56 chromosome X open reading frame 56
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DNA2 DNA replication helicase/nuclease 2
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
FAM193B family with sequence similarity 193, member B
FCHO1 FCH domain only 1
FKBP10 FK506 binding protein 10, 65 kDa
FPGS folylpolyglutamate synthase
FSD1 fibronectin type III and SPRY domain containing 1
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
FXR2 fragile X mental retardation, autosomal homolog 2
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GMEB1 glucocorticoid modulatory element binding protein 1
GPHN gephyrin
GPR87 G protein-coupled receptor 87
HMGB3 high mobility group box 3
IFT81 intraflagellar transport 81
IL17RA interleukin 17 receptor A
KCTD20 potassium channel tetramerization domain containing 20
KIAA0753 KIAA0753
KIAA0894 KIAA0894 protein
KLHL26 kelch-like family member 26
KRT13 keratin 13, type I
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LOC730101 uncharacterized LOC730101
LRP5 low density lipoprotein receptor-related protein 5
LRP5L low density lipoprotein receptor-related protein 5-like
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MAGEF1 melanoma antigen family F1
MRPL44 mitochondrial ribosomal protein L44
MXD3 MAX dimerization protein 3
MYNN myoneurin
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
OLFML3 olfactomedin-like 3
OXSR1 oxidative stress responsive 1
PARG poly (ADP-ribose) glycohydrolase
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2
PHF21A PHD finger protein 21A
PHKB phosphorylase kinase, beta
PKD2 polycystic kidney disease 2 (autosomal dominant)
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PMP22 peripheral myelin protein 22
PODXL podocalyxin-like
POR P450 (cytochrome) oxidoreductase
PPAN peter pan homolog (Drosophila)
PRR14L proline rich 14-like
PTDSS2 phosphatidylserine synthase 2
PTGES2 prostaglandin E synthase 2
PTPRU protein tyrosine phosphatase, receptor type, U
QSOX1 quiescin Q6 sulfhydryl oxidase 1
QTRT1 queuine tRNA-ribosyltransferase 1
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RGS17 regulator of G-protein signaling 17
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SKA1 spindle and kinetochore associated complex subunit 1
SLC16A6 solute carrier family 16, member 6
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC46A3 solute carrier family 46, member 3
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
STBD1 starch binding domain 1
STEAP3 STEAP family member 3, metalloreductase
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TDRD1 tudor domain containing 1
TEAD3 TEA domain family member 3
THAP1 THAP domain containing, apoptosis associated protein 1
TMEM104 transmembrane protein 104
TMEM115 transmembrane protein 115
TMEM184C transmembrane protein 184C
TRIM25 tripartite motif containing 25
TSPAN15 tetraspanin 15
ZNF276 zinc finger protein 276
ZNF280D zinc finger protein 280D
ZNF552 zinc finger protein 552
ZNF668 zinc finger protein 668
ZNF8 zinc finger protein 8
ZNF816 zinc finger protein 816
ZSCAN5A zinc finger and SCAN domain containing 5A
ZXDC ZXD family zinc finger C