thiethylperazine-5756 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the thiethylperazine-5756 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ALDOB aldolase B, fructose-bisphosphate
ANG angiogenin, ribonuclease, RNase A family, 5
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
ARHGAP28 Rho GTPase activating protein 28
ATHL1 ATH1, acid trehalase-like 1 (yeast)
BMP5 bone morphogenetic protein 5
C11ORF63 chromosome 11 open reading frame 63
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CA5B carbonic anhydrase VB, mitochondrial
CCL27 chemokine (C-C motif) ligand 27
CCNA1 cyclin A1
CCPG1 cell cycle progression 1
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CNPY4 canopy FGF signaling regulator 4
COL7A1 collagen, type VII, alpha 1
CXCR4 chemokine (C-X-C motif) receptor 4
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DDO D-aspartate oxidase
DMBT1 deleted in malignant brain tumors 1
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DOC2A double C2-like domains, alpha
DPY19L1P1 DPY19L1 pseudogene 1
DSTYK dual serine/threonine and tyrosine protein kinase
EFNA3 ephrin-A3
ELOVL5 ELOVL fatty acid elongase 5
EPS8L1 EPS8-like 1
FAM46C family with sequence similarity 46, member C
FBXL18 F-box and leucine-rich repeat protein 18
FBXO4 F-box protein 4
GK3P glycerol kinase 3 pseudogene
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOOK1 hook microtubule-tethering protein 1
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL1RN interleukin 1 receptor antagonist
IL36G interleukin 36, gamma
IL6ST interleukin 6 signal transducer
INSIG1 insulin induced gene 1
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
KCTD14 potassium channel tetramerization domain containing 14
LAMA4 laminin, alpha 4
LENEP lens epithelial protein
MAN2A2 mannosidase, alpha, class 2A, member 2
MOCS1 molybdenum cofactor synthesis 1
MST1 macrophage stimulating 1
MTMR8 myotubularin related protein 8
MUC3B mucin 3B, cell surface associated
NDRG1 N-myc downstream regulated 1
NF1 neurofibromin 1
NPC1 Niemann-Pick disease, type C1
NPTX1 neuronal pentraxin I
NR2E3 nuclear receptor subfamily 2, group E, member 3
NUPR1 nuclear protein, transcriptional regulator, 1
NYX nyctalopin
OVOL1 ovo-like zinc finger 1
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDE4D phosphodiesterase 4D, cAMP-specific
PKNOX2 PBX/knotted 1 homeobox 2
PRAF2 PRA1 domain family, member 2
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PTPRR protein tyrosine phosphatase, receptor type, R
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGS12 regulator of G-protein signaling 12
RIMS3 regulating synaptic membrane exocytosis 3
RNF43 ring finger protein 43
RPL10 ribosomal protein L10
RPP25 ribonuclease P/MRP 25kDa subunit
S100A11 S100 calcium binding protein A11
S100A5 S100 calcium binding protein A5
SARM1 sterile alpha and TIR motif containing 1
SARS2 seryl-tRNA synthetase 2, mitochondrial
SEC14L4 SEC14-like 4 (S. cerevisiae)
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SQSTM1 sequestosome 1
SRF serum response factor (c-fos serum response element-binding transcription factor)
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
SYT1 synaptotagmin I
TAGLN3 transgelin 3
TFR2 transferrin receptor 2
THRB thyroid hormone receptor, beta
TRA T cell receptor alpha locus
UBXN1 UBX domain protein 1
UPK3B uroplakin 3B
USP27X ubiquitin specific peptidase 27, X-linked
ZER1 zyg-11 related, cell cycle regulator
ZNF280B zinc finger protein 280B

decreased expression

Symbol Name
ACBD4 acyl-CoA binding domain containing 4
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ANOS1 anosmin 1
ANP32A-IT1 ANP32A intronic transcript 1
ANXA10 annexin A10
APOLD1 apolipoprotein L domain containing 1
ASAP1-IT1 ASAP1 intronic transcript 1
ASB13 ankyrin repeat and SOCS box containing 13
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
BDH1 3-hydroxybutyrate dehydrogenase, type 1
BEX1 brain expressed, X-linked 1
BHLHB9 basic helix-loop-helix domain containing, class B, 9
C1QTNF3 C1q and tumor necrosis factor related protein 3
CA8 carbonic anhydrase VIII
CDK3 cyclin-dependent kinase 3
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
COBL cordon-bleu WH2 repeat protein
DENND2D DENN/MADD domain containing 2D
DEPTOR DEP domain containing MTOR-interacting protein
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
EPHX2 epoxide hydrolase 2, cytoplasmic
ERCC2 excision repair cross-complementation group 2
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM120C family with sequence similarity 120C
FAM184A family with sequence similarity 184, member A
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FBRS fibrosin
FBXO2 F-box protein 2
GALK1 galactokinase 1
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GLS2 glutaminase 2 (liver, mitochondrial)
GRB7 growth factor receptor-bound protein 7
GRPR gastrin-releasing peptide receptor
GSTCD glutathione S-transferase, C-terminal domain containing
HIST1H2AJ histone cluster 1, H2aj
HOXC10 homeobox C10
HOXC13 homeobox C13
HSF2BP heat shock transcription factor 2 binding protein
IL12A interleukin 12A
ITK IL2-inducible T-cell kinase
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KRT31 keratin 31, type I
KRT4 keratin 4, type II
KRT9 keratin 9, type I
LIMS2 LIM and senescent cell antigen-like domains 2
LRP3 low density lipoprotein receptor-related protein 3
LRRC37A3 leucine rich repeat containing 37, member A3
LRRC61 leucine rich repeat containing 61
LYPD1 LY6/PLAUR domain containing 1
LYPD3 LY6/PLAUR domain containing 3
MAGEB2 melanoma antigen family B2
MBTPS2 membrane-bound transcription factor peptidase, site 2
MCTP2 multiple C2 domains, transmembrane 2
MDFI MyoD family inhibitor
MFSD6 major facilitator superfamily domain containing 6
MILR1 mast cell immunoglobulin-like receptor 1
MOXD1 monooxygenase, DBH-like 1
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MYBBP1A MYB binding protein (P160) 1a
NDP Norrie disease (pseudoglioma)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOL12 nucleolar protein 12
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
NPM3 nucleophosmin/nucleoplasmin 3
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
P3H2 prolyl 3-hydroxylase 2
PAN2 PAN2 poly(A) specific ribonuclease subunit
PENK proenkephalin
PLXNA3 plexin A3
PRAMEF11 PRAME family member 11
RAB3A RAB3A, member RAS oncogene family
RIBC2 RIB43A domain with coiled-coils 2
ROM1 retinal outer segment membrane protein 1
S100A3 S100 calcium binding protein A3
SH2D2A SH2 domain containing 2A
SH3BGR SH3 domain binding glutamate-rich protein
SLC46A3 solute carrier family 46, member 3
STAG3 stromal antigen 3
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAOK1 TAO kinase 1
TECPR2 tectonin beta-propeller repeat containing 2
THBS3 thrombospondin 3
TMEM53 transmembrane protein 53
TRIM25 tripartite motif containing 25
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRPM4 transient receptor potential cation channel, subfamily M, member 4
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
ZBTB39 zinc finger and BTB domain containing 39
ZFHX2 zinc finger homeobox 2
ZNF137P zinc finger protein 137, pseudogene
ZNF239 zinc finger protein 239
ZNF358 zinc finger protein 358
ZNF415 zinc finger protein 415
ZNF428 zinc finger protein 428
ZNF74 zinc finger protein 74
ZNF8 zinc finger protein 8
ZNF862 zinc finger protein 862