testosterone-2649 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the testosterone-2649 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ADAMTSL3 ADAMTS-like 3
ADCK4 aarF domain containing kinase 4
AHDC1 AT hook, DNA binding motif, containing 1
AKAP11 A kinase (PRKA) anchor protein 11
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ARHGAP1 Rho GTPase activating protein 1
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARMCX4 armadillo repeat containing, X-linked 4
ATF7IP activating transcription factor 7 interacting protein
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
BTF3P11 basic transcription factor 3 pseudogene 11
C1QL1 complement component 1, q subcomponent-like 1
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CAMK1D calcium/calmodulin-dependent protein kinase ID
CCDC40 coiled-coil domain containing 40
CD1B CD1b molecule
CLPS colipase, pancreatic
CORT cortistatin
CPN2 carboxypeptidase N, polypeptide 2
CSRP2 cysteine and glycine-rich protein 2
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DTNB dystrobrevin, beta
EFCAB6 EF-hand calcium binding domain 6
ETV7 ets variant 7
FLJ22184
FSTL3 follistatin-like 3 (secreted glycoprotein)
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GRB10 growth factor receptor-bound protein 10
GSTCD glutathione S-transferase, C-terminal domain containing
GZMK granzyme K (granzyme 3; tryptase II)
HLA-DMA major histocompatibility complex, class II, DM alpha
HOXC5 homeobox C5
HOXC8 homeobox C8
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
IGFBP5 insulin-like growth factor binding protein 5
IGL immunoglobulin lambda locus
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IL2 interleukin 2
IL4 interleukin 4
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIAA1456 KIAA1456
LMNA lamin A/C
LTBP2 latent transforming growth factor beta binding protein 2
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MBD2 methyl-CpG binding domain protein 2
MCAM melanoma cell adhesion molecule
MDFI MyoD family inhibitor
MMP3 matrix metallopeptidase 3
MPPE1 metallophosphoesterase 1
MUC2 mucin 2, oligomeric mucus/gel-forming
N4BP1 NEDD4 binding protein 1
NCALD neurocalcin delta
NF2 neurofibromin 2 (merlin)
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFIB nuclear factor I/B
NPTX1 neuronal pentraxin I
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRN1 neuritin 1
OR2B6 olfactory receptor, family 2, subfamily B, member 6
OR52A1 olfactory receptor, family 52, subfamily A, member 1
PCDHB8 protocadherin beta 8
PLK4 polo-like kinase 4
PLXNB3 plexin B3
POLM polymerase (DNA directed), mu
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PPP5C protein phosphatase 5, catalytic subunit
PRPH peripherin
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGIS prostaglandin I2 (prostacyclin) synthase
PURA purine-rich element binding protein A
RARA retinoic acid receptor, alpha
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RGS11 regulator of G-protein signaling 11
RPL23AP32 ribosomal protein L23a pseudogene 32
SCUBE3 signal peptide, CUB domain, EGF-like 3
SLC22A17 solute carrier family 22, member 17
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLIT2 slit homolog 2 (Drosophila)
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
STX7 syntaxin 7
SYMPK symplekin
SYN3 synapsin III
TAT tyrosine aminotransferase
TMCC2 transmembrane and coiled-coil domain family 2
TMEM158 transmembrane protein 158 (gene/pseudogene)
TRAF3IP2 TRAF3 interacting protein 2
TRIM25 tripartite motif containing 25
UPK3A uroplakin 3A
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
WNT16 wingless-type MMTV integration site family, member 16
ZNF440 zinc finger protein 440
ZNF696 zinc finger protein 696

decreased expression

Symbol Name
AFF4 AF4/FMR2 family, member 4
ALPK1 alpha-kinase 1
ANKRD40 ankyrin repeat domain 40
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ASTN2 astrotactin 2
ATG2B autophagy related 2B
BMP4 bone morphogenetic protein 4
C14ORF132 chromosome 14 open reading frame 132
C14ORF93 chromosome 14 open reading frame 93
C17ORF80 chromosome 17 open reading frame 80
CARD8 caspase recruitment domain family, member 8
CHKB choline kinase beta
CLDN15 claudin 15
CLSPN claspin
CNN2 calponin 2
COG4 component of oligomeric golgi complex 4
COL4A5 collagen, type IV, alpha 5
COL9A2 collagen, type IX, alpha 2
COPS7B COP9 signalosome subunit 7B
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CSTA cystatin A (stefin A)
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
DAGLA diacylglycerol lipase, alpha
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DSCAM Down syndrome cell adhesion molecule
DUSP13 dual specificity phosphatase 13
EFNA3 ephrin-A3
EHD3 EH-domain containing 3
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EXD3 exonuclease 3'-5' domain containing 3
EXTL2 exostosin-like glycosyltransferase 2
FBXL2 F-box and leucine-rich repeat protein 2
FBXW12 F-box and WD repeat domain containing 12
FCHSD2 FCH and double SH3 domains 2
FPGS folylpolyglutamate synthase
GAMT guanidinoacetate N-methyltransferase
GEMIN8 gem (nuclear organelle) associated protein 8
GINS4 GINS complex subunit 4 (Sld5 homolog)
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GLI3 GLI family zinc finger 3
GPR19 G protein-coupled receptor 19
GRB7 growth factor receptor-bound protein 7
HIRA histone cell cycle regulator
HIST1H2BJ histone cluster 1, H2bj
HIST1H2BO histone cluster 1, H2bo
HLA-J major histocompatibility complex, class I, J (pseudogene)
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL4R interleukin 4 receptor
INTS9 integrator complex subunit 9
IPO8 importin 8
KAT2A K(lysine) acetyltransferase 2A
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KDM5C lysine (K)-specific demethylase 5C
LARP6 La ribonucleoprotein domain family, member 6
LHX1 LIM homeobox 1
LIN7A lin-7 homolog A (C. elegans)
LINC00115 long intergenic non-protein coding RNA 115
LOC390998 ribosomal protein L10 pseudogene
LOC642236 FSHD region gene 1 pseudogene
LRRC8E leucine rich repeat containing 8 family, member E
LYPD3 LY6/PLAUR domain containing 3
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MXD3 MAX dimerization protein 3
OTUD3 OTU deubiquitinase 3
PADI1 peptidyl arginine deiminase, type I
PC pyruvate carboxylase
PDGFRL platelet-derived growth factor receptor-like
PDIA3 protein disulfide isomerase family A, member 3
PEX26 peroxisomal biogenesis factor 26
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHO2 pleckstrin homology domain containing, family O member 2
PRICKLE3 prickle homolog 3 (Drosophila)
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRSS22 protease, serine, 22
RAB8B RAB8B, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RFTN1 raftlin, lipid raft linker 1
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RPAP2 RNA polymerase II associated protein 2
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SGK1 serum/glucocorticoid regulated kinase 1
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC46A3 solute carrier family 46, member 3
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SOX12 SRY (sex determining region Y)-box 12
SOX3 SRY (sex determining region Y)-box 3
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STK16 serine/threonine kinase 16
SUN2 Sad1 and UNC84 domain containing 2
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TRPM4 transient receptor potential cation channel, subfamily M, member 4
WRN Werner syndrome, RecQ helicase-like
ZNF324 zinc finger protein 324
ZNF329 zinc finger protein 329
ZNF652 zinc finger protein 652
ZNF665 zinc finger protein 665
ZNF669 zinc finger protein 669