terguride-6299 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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200 genes differentially expressed following the terguride-6299 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANXA10 annexin A10
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATP9A ATPase, class II, type 9A
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BICC1 BicC family RNA binding protein 1
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CD58 CD58 molecule
CDK9 cyclin-dependent kinase 9
CEP295 centrosomal protein 295kDa
CLTA clathrin, light chain A
CNTLN centlein, centrosomal protein
COL9A2 collagen, type IX, alpha 2
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
CORO1B coronin, actin binding protein, 1B
CREB5 cAMP responsive element binding protein 5
CTNS cystinosin, lysosomal cystine transporter
CTSZ cathepsin Z
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DCAF7 DDB1 and CUL4 associated factor 7
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DTNA dystrobrevin, alpha
DUSP9 dual specificity phosphatase 9
EDIL3 EGF-like repeats and discoidin I-like domains 3
EFNA3 ephrin-A3
EML3 echinoderm microtubule associated protein like 3
EPS8L3 EPS8-like 3
ERN2 endoplasmic reticulum to nucleus signaling 2
FADS2 fatty acid desaturase 2
FILIP1L filamin A interacting protein 1-like
FUBP1 far upstream element (FUSE) binding protein 1
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GM2A GM2 ganglioside activator
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HIRA histone cell cycle regulator
HMG20B high mobility group 20B
HOXB2 homeobox B2
ICOSLG inducible T-cell co-stimulator ligand
IL1R2 interleukin 1 receptor, type II
IL6ST interleukin 6 signal transducer
JRK Jrk homolog (mouse)
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KLHDC3 kelch domain containing 3
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LEF1 lymphoid enhancer-binding factor 1
LTC4S leukotriene C4 synthase
MED14 mediator complex subunit 14
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NHLRC2 NHL repeat containing 2
NINJ1 ninjurin 1
NPEPL1 aminopeptidase-like 1
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
PAIP2B poly(A) binding protein interacting protein 2B
PARP3 poly (ADP-ribose) polymerase family, member 3
PDE4DIP phosphodiesterase 4D interacting protein
PHLDB1 pleckstrin homology-like domain, family B, member 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PMFBP1 polyamine modulated factor 1 binding protein 1
POLG polymerase (DNA directed), gamma
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PPP1R7 protein phosphatase 1, regulatory subunit 7
PRICKLE3 prickle homolog 3 (Drosophila)
PRLH prolactin releasing hormone
PTK6 protein tyrosine kinase 6
RAD54L2 RAD54-like 2 (S. cerevisiae)
RARG retinoic acid receptor, gamma
RECQL5 RecQ protein-like 5
RGS10 regulator of G-protein signaling 10
RHEB Ras homolog enriched in brain
SCAMP1 secretory carrier membrane protein 1
SCARB1 scavenger receptor class B, member 1
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SGSH N-sulfoglucosamine sulfohydrolase
SIRT5 sirtuin 5
SIX1 SIX homeobox 1
SLC46A3 solute carrier family 46, member 3
SLCO2B1 solute carrier organic anion transporter family, member 2B1
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SMR3A submaxillary gland androgen regulated protein 3A
SPRYD7 SPRY domain containing 7
SRSF1 serine/arginine-rich splicing factor 1
STAC SH3 and cysteine rich domain
SUGP1 SURP and G patch domain containing 1
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae)
TIAM1 T-cell lymphoma invasion and metastasis 1
TK2 thymidine kinase 2, mitochondrial
TMEM53 transmembrane protein 53
TRABD TraB domain containing
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WNK1 WNK lysine deficient protein kinase 1
ZHX3 zinc fingers and homeoboxes 3
ZNF227 zinc finger protein 227
ZNF528 zinc finger protein 528

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ALS2CL ALS2 C-terminal like
AMBRA1 autophagy/beclin-1 regulator 1
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BAHD1 bromo adjacent homology domain containing 1
BIK BCL2-interacting killer (apoptosis-inducing)
BRAF B-Raf proto-oncogene, serine/threonine kinase
C17ORF70 chromosome 17 open reading frame 70
C1ORF112 chromosome 1 open reading frame 112
CCDC9 coiled-coil domain containing 9
CDK3 cyclin-dependent kinase 3
CFAP44 cilia and flagella associated protein 44
CHMP6 charged multivesicular body protein 6
CINP cyclin-dependent kinase 2 interacting protein
COG7 component of oligomeric golgi complex 7
CRYBB2P1 crystallin, beta B2 pseudogene 1
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DCLRE1A DNA cross-link repair 1A
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
EDC4 enhancer of mRNA decapping 4
ELP3 elongator acetyltransferase complex subunit 3
ENO2 enolase 2 (gamma, neuronal)
ERCC2 excision repair cross-complementation group 2
ETV4 ets variant 4
FAM102A family with sequence similarity 102, member A
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FPGS folylpolyglutamate synthase
GDAP1 ganglioside induced differentiation associated protein 1
GPRC5A G protein-coupled receptor, class C, group 5, member A
GTPBP2 GTP binding protein 2
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
HIST1H2BJ histone cluster 1, H2bj
HOXC13 homeobox C13
IDI2-AS1 IDI2 antisense RNA 1
IFI35 interferon-induced protein 35
IFNAR1 interferon (alpha, beta and omega) receptor 1
IL24 interleukin 24
JMJD4 jumonji domain containing 4
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LUC7L LUC7-like (S. cerevisiae)
MAGEF1 melanoma antigen family F1
MN1 meningioma (disrupted in balanced translocation) 1
MRPS18C mitochondrial ribosomal protein S18C
NECAP2 NECAP endocytosis associated 2
NLRX1 NLR family member X1
NUBP1 nucleotide binding protein 1
OCLN occludin
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PARD6A par-6 family cell polarity regulator alpha
PC pyruvate carboxylase
PCDHGB5 protocadherin gamma subfamily B, 5
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PDE12 phosphodiesterase 12
PHKG2 phosphorylase kinase, gamma 2 (testis)
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PLD2 phospholipase D2
PRR7 proline rich 7 (synaptic)
QTRT1 queuine tRNA-ribosyltransferase 1
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RNF31 ring finger protein 31
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPAP2 RNA polymerase II associated protein 2
RUSC2 RUN and SH3 domain containing 2
SIPA1 signal-induced proliferation-associated 1
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SND1-IT1 SND1 intronic transcript 1
SPATA2L spermatogenesis associated 2-like
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAOK1 TAO kinase 1
TEAD3 TEA domain family member 3
TEX40 testis expressed 40
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast)
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM132A transmembrane protein 132A
TMEM62 transmembrane protein 62
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TOR4A torsin family 4, member A
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TUBA3C tubulin, alpha 3c
TUBG2 tubulin, gamma 2
ULBP2 UL16 binding protein 2
UNC119 unc-119 homolog (C. elegans)
UNKL unkempt family zinc finger-like
USB1 U6 snRNA biogenesis 1
USP27X ubiquitin specific peptidase 27, X-linked
VWA1 von Willebrand factor A domain containing 1
ZBED1 zinc finger, BED-type containing 1
ZFP36 ZFP36 ring finger protein
ZNF134 zinc finger protein 134
ZNF214 zinc finger protein 214
ZNF358 zinc finger protein 358
ZNF611 zinc finger protein 611
ZNF692 zinc finger protein 692