terbutaline-6240 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the terbutaline-6240 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif, 8
AFF4 AF4/FMR2 family, member 4
AKR1C1 aldo-keto reductase family 1, member C1
AOX1 aldehyde oxidase 1
APLP1 amyloid beta (A4) precursor-like protein 1
APOC1 apolipoprotein C-I
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ARID1A AT rich interactive domain 1A (SWI-like)
AZGP1 alpha-2-glycoprotein 1, zinc-binding
C7ORF43 chromosome 7 open reading frame 43
CD44 CD44 molecule (Indian blood group)
CDADC1 cytidine and dCMP deaminase domain containing 1
CDKN2A cyclin-dependent kinase inhibitor 2A
CDON cell adhesion associated, oncogene regulated
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CLCN3 chloride channel, voltage-sensitive 3
COL1A1 collagen, type I, alpha 1
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CXORF21 chromosome X open reading frame 21
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DESI2 desumoylating isopeptidase 2
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
EML3 echinoderm microtubule associated protein like 3
F3 coagulation factor III (thromboplastin, tissue factor)
FANCE Fanconi anemia, complementation group E
FILIP1L filamin A interacting protein 1-like
FKBP8 FK506 binding protein 8, 38kDa
FLOT1 flotillin 1
FMOD fibromodulin
FOXN2 forkhead box N2
FOXN3 forkhead box N3
FRMD4B FERM domain containing 4B
FSCN1 fascin actin-bundling protein 1
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GADD45G growth arrest and DNA-damage-inducible, gamma
GRK4 G protein-coupled receptor kinase 4
HDLBP high density lipoprotein binding protein
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HIRA histone cell cycle regulator
HIST1H2AJ histone cluster 1, H2aj
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
ICAM1 intercellular adhesion molecule 1
IGHA1 immunoglobulin heavy constant alpha 1
IL2 interleukin 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
JRK Jrk homolog (mouse)
KCNK10 potassium channel, two pore domain subfamily K, member 10
KIAA1456 KIAA1456
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KLF5 Kruppel-like factor 5 (intestinal)
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LY9 lymphocyte antigen 9
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MTAP methylthioadenosine phosphorylase
NEBL nebulette
NID1 nidogen 1
OLFM4 olfactomedin 4
PCDH12 protocadherin 12
PCDHB3 protocadherin beta 3
PCDHGA11 protocadherin gamma subfamily A, 11
PIPOX pipecolic acid oxidase
PLA2G15 phospholipase A2, group XV
PLA2G5 phospholipase A2, group V
PRUNE2 prune homolog 2 (Drosophila)
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB3A RAB3A, member RAS oncogene family
RBP4 retinol binding protein 4, plasma
RIMS3 regulating synaptic membrane exocytosis 3
RIN3 Ras and Rab interactor 3
RNF122 ring finger protein 122
RNF19B ring finger protein 19B
RPAIN RPA interacting protein
RPGR retinitis pigmentosa GTPase regulator
RPS3A ribosomal protein S3A
RTEL1 regulator of telomere elongation helicase 1
SBNO2 strawberry notch homolog 2 (Drosophila)
SCARB1 scavenger receptor class B, member 1
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SPAG8 sperm associated antigen 8
SPTBN1 spectrin, beta, non-erythrocytic 1
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
STK38L serine/threonine kinase 38 like
SUGP1 SURP and G patch domain containing 1
TDRKH tudor and KH domain containing
TRIM62 tripartite motif containing 62
UBA7 ubiquitin-like modifier activating enzyme 7
VIPR2 vasoactive intestinal peptide receptor 2
ZBTB43 zinc finger and BTB domain containing 43
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF442 zinc finger protein 442
ZSCAN12 zinc finger and SCAN domain containing 12

decreased expression

Symbol Name
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARMC7 armadillo repeat containing 7
ATP13A2 ATPase type 13A2
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
C10ORF88 chromosome 10 open reading frame 88
C11ORF95 chromosome 11 open reading frame 95
C12ORF4 chromosome 12 open reading frame 4
C17ORF70 chromosome 17 open reading frame 70
C1ORF35 chromosome 1 open reading frame 35
CAPG capping protein (actin filament), gelsolin-like
CARD8 caspase recruitment domain family, member 8
CASP3 caspase 3, apoptosis-related cysteine peptidase
CDK3 cyclin-dependent kinase 3
CEP85 centrosomal protein 85kDa
CGREF1 cell growth regulator with EF-hand domain 1
CLDND1 claudin domain containing 1
CLEC16A C-type lectin domain family 16, member A
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CTNNBL1 catenin, beta like 1
CUEDC1 CUE domain containing 1
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DKFZP586I1420 uncharacterized protein DKFZp586I1420
DOCK1 dedicator of cytokinesis 1
DOLK dolichol kinase
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
ECHDC3 enoyl CoA hydratase domain containing 3
EPPK1 epiplakin 1
FAM189B family with sequence similarity 189, member B
FKBPL FK506 binding protein like
FPGS folylpolyglutamate synthase
GAB2 GRB2-associated binding protein 2
GBAS glioblastoma amplified sequence
GHR growth hormone receptor
GMEB1 glucocorticoid modulatory element binding protein 1
GNPDA1 glucosamine-6-phosphate deaminase 1
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa
GUF1 GUF1 GTPase homolog (S. cerevisiae)
HIRIP3 HIRA interacting protein 3
HMHA1 histocompatibility (minor) HA-1
HOXA5 homeobox A5
HTRA1 HtrA serine peptidase 1
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
INPP5F inositol polyphosphate-5-phosphatase F
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
JUNB jun B proto-oncogene
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KCTD20 potassium channel tetramerization domain containing 20
KIAA0556 KIAA0556
KIF16B kinesin family member 16B
KLHL2 kelch-like family member 2
KLHL21 kelch-like family member 21
KRT13 keratin 13, type I
LRRC20 leucine rich repeat containing 20
LRRC42 leucine rich repeat containing 42
MBTPS2 membrane-bound transcription factor peptidase, site 2
MIS18BP1 MIS18 binding protein 1
MORC3 MORC family CW-type zinc finger 3
MPHOSPH8 M-phase phosphoprotein 8
NECAB3 N-terminal EF-hand calcium binding protein 3
NINL ninein-like
NR1H3 nuclear receptor subfamily 1, group H, member 3
PAQR6 progestin and adipoQ receptor family member VI
PCSK7 proprotein convertase subtilisin/kexin type 7
PEX26 peroxisomal biogenesis factor 26
PHACTR4 phosphatase and actin regulator 4
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PMP22 peripheral myelin protein 22
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
POLI polymerase (DNA directed) iota
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
POT1 protection of telomeres 1
RABL6 RAB, member RAS oncogene family-like 6
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
REEP4 receptor accessory protein 4
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
RINT1 RAD50 interactor 1
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SCAP SREBF chaperone
SECISBP2 SECIS binding protein 2
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SLC25A40 solute carrier family 25, member 40
SLC46A3 solute carrier family 46, member 3
SNIP1 Smad nuclear interacting protein 1
SPATA7 spermatogenesis associated 7
STARD13 StAR-related lipid transfer (START) domain containing 13
TGFBI transforming growth factor, beta-induced, 68kDa
TRIM25 tripartite motif containing 25
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like
VAV1 vav 1 guanine nucleotide exchange factor
WWC2 WW and C2 domain containing 2
ZMAT5 zinc finger, matrin-type 5
ZNF106 zinc finger protein 106
ZNF268 zinc finger protein 268
ZNF276 zinc finger protein 276
ZNF408 zinc finger protein 408