telomere cap complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A complex of DNA and protein located at the end of a linear chromosome that protects and stabilizes a linear chromosome. (Gene Ontology, GO_0000782)
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Genes

86 proteins co-occuring with the telomere cap complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
TINF2 TERF1 (TRF1)-interacting nuclear factor 2 2.85847
TERF1 telomeric repeat binding factor (NIMA-interacting) 1 2.74871
POT1 protection of telomeres 1 2.67707
CTC1 CTS telomere maintenance complex component 1 1.78649
TERF2 telomeric repeat binding factor 2 1.52936
TERT telomerase reverse transcriptase 1.50791
NOP10 NOP10 ribonucleoprotein 1.49267
ATM ATM serine/threonine kinase 1.47683
DKC1 dyskeratosis congenita 1, dyskerin 1.46156
NHP2 NHP2 ribonucleoprotein 1.37188
ACD adrenocortical dysplasia homolog (mouse) 1.19108
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 1.15262
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) 1.1245
EXO1 exonuclease 1 1.02679
USB1 U6 snRNA biogenesis 1 0.996123
RTEL1 regulator of telomere elongation helicase 1 0.990247
RAD50 RAD50 homolog (S. cerevisiae) 0.961187
TP53BP1 tumor protein p53 binding protein 1 0.944956
C9ORF78 chromosome 9 open reading frame 78 0.911579
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.870885
ZNF827 zinc finger protein 827 0.860311
MTRF1 mitochondrial translational release factor 1 0.848828
ATR ATR serine/threonine kinase 0.795604
H2AFX H2A histone family, member X 0.767715
ZSCAN4 zinc finger and SCAN domain containing 4 0.723026
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1 0.705273
CGGBP1 CGG triplet repeat binding protein 1 0.684644
TERF2IP telomeric repeat binding factor 2, interacting protein 0.679413
TRIP6 thyroid hormone receptor interactor 6 0.662935
STAG1 stromal antigen 1 0.657326
SLX4 SLX4 structure-specific endonuclease subunit 0.636295
CHEK1 checkpoint kinase 1 0.617557
HMBOX1 homeobox containing 1 0.607395
RECQL4 RecQ protein-like 4 0.583849
RLIM ring finger protein, LIM domain interacting 0.569664
NBN nibrin 0.567585
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) 0.566338
LPP LIM domain containing preferred translocation partner in lipoma 0.535772
ZC3H12D zinc finger CCCH-type containing 12D 0.532898
SMG6 SMG6 nonsense mediated mRNA decay factor 0.506757
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like 0.503506
USP22 ubiquitin specific peptidase 22 0.493371
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A 0.48005
LRWD1 leucine-rich repeats and WD repeat domain containing 1 0.472011
OBFC1 oligonucleotide/oligosaccharide-binding fold containing 1 0.440124
LIG4 ligase IV, DNA, ATP-dependent 0.438542
TP53 tumor protein p53 0.432224
FRMD6 FERM domain containing 6 0.422389
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.403637
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 0.391228
TPSG1 tryptase gamma 1 0.390068
SMN1 survival of motor neuron 1, telomeric 0.388137
IGH immunoglobulin heavy locus 0.387751
RAD54B RAD54 homolog B (S. cerevisiae) 0.383509
COPS2 COP9 signalosome subunit 2 0.37697
MRI1 methylthioribose-1-phosphate isomerase 1 0.37045
PARK2 parkin RBR E3 ubiquitin protein ligase 0.368153
BOLL boule-like RNA-binding protein 0.366623
SIAH2 siah E3 ubiquitin protein ligase 2 0.365859
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase 0.356705
SNW1 SNW domain containing 1 0.332472
RECQL RecQ helicase-like 0.329461
SMN2 survival of motor neuron 2, centromeric 0.297713
WRN Werner syndrome, RecQ helicase-like 0.267871
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.260202
BRIP1 BRCA1 interacting protein C-terminal helicase 1 0.256925
RNF168 ring finger protein 168, E3 ubiquitin protein ligase 0.248578
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.236324
TFR2 transferrin receptor 2 0.235249
PIF1 PIF1 5'-to-3' DNA helicase 0.232386
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.22173
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa 0.219617
MCM6 minichromosome maintenance complex component 6 0.218212
TIMELESS timeless circadian clock 0.213322
SIAH1 siah E3 ubiquitin protein ligase 1 0.203699
BRCA1 breast cancer 1, early onset 0.202346
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast) 0.201672
MYB v-myb avian myeloblastosis viral oncogene homolog 0.191777
TPP1 tripeptidyl peptidase I 0.177724
RAD17 RAD17 homolog (S. pombe) 0.175745
ATRIP ATR interacting protein 0.175188
SUN1 Sad1 and UNC84 domain containing 1 0.167611
PARP1 poly (ADP-ribose) polymerase 1 0.166643
DNA2 DNA replication helicase/nuclease 2 0.160863
RPA2 replication protein A2, 32kDa 0.138011
CDK1 cyclin-dependent kinase 1 0.126939