t cell receptor complex Gene Set

Dataset GO Cellular Component Annotations
Category structural or functional annotations
Type cellular component
Description A protein complex that contains a disulfide-linked heterodimer of T cell receptor (TCR) chains, which are members of the immunoglobulin superfamily, and mediates antigen recognition, ultimately resulting in T cell activation. The TCR heterodimer is associated with the CD3 complex, which consists of the nonpolymorphic polypeptides gamma, delta, epsilon, zeta, and, in some cases, eta (an RNA splice variant of zeta) or Fc epsilon chains. (Gene Ontology, GO_0042101)
External Link http://amigo.geneontology.org/amigo/term/GO:0042101
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Genes

14 proteins localized to the t cell receptor complex cellular component from the curated GO Cellular Component Annotations dataset.

Symbol Name
BCL10 B-cell CLL/lymphoma 10
CARD11 caspase recruitment domain family, member 11
CD247 CD247 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD4 CD4 molecule
CD8A CD8a molecule
CD8B CD8b molecule
PTPN6 protein tyrosine phosphatase, non-receptor type 6
STOML2 stomatin (EPB72)-like 2
SYK spleen tyrosine kinase
TRAT1 T cell receptor associated transmembrane adaptor 1
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa