synovial fibroblast Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
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Genes

327 proteins co-occuring with the tissue synovial fibroblast in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
MMP1 matrix metallopeptidase 1 2.11819
MMP3 matrix metallopeptidase 3 2.11766
IL1B interleukin 1, beta 2.10859
TNF tumor necrosis factor 1.68254
MMP13 matrix metallopeptidase 13 1.63956
TIMP1 TIMP metallopeptidase inhibitor 1 1.46449
IL1A interleukin 1, alpha 1.4357
IL6 interleukin 6 1.24922
IL1RN interleukin 1 receptor antagonist 1.24922
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.22871
CCL2 chemokine (C-C motif) ligand 2 1.21401
OSM oncostatin M 1.17624
MMP2 matrix metallopeptidase 2 1.1554
PMFBP1 polyamine modulated factor 1 binding protein 1 1.14609
TGFB1 transforming growth factor, beta 1 1.11818
MMP14 matrix metallopeptidase 14 (membrane-inserted) 1.09562
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 1.07529
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 1.04664
VCAM1 vascular cell adhesion molecule 1 1.03961
PLG plasminogen 1.02337
IL17A interleukin 17A 1.0085
ACAN aggrecan 0.984556
TLR2 toll-like receptor 2 0.984122
ICAM1 intercellular adhesion molecule 1 0.976749
CXCL8 chemokine (C-X-C motif) ligand 8 0.975015
COMP cartilage oligomeric matrix protein 0.952547
TLR4 toll-like receptor 4 0.952547
CD68 CD68 molecule 0.950393
SAAL1 serum amyloid A-like 1 0.949101
JUN jun proto-oncogene 0.945226
KANK4 KN motif and ankyrin repeat domains 4 0.935341
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 0.916496
FN1 fibronectin 1 0.898595
MMP9 matrix metallopeptidase 9 0.89477
TIMP2 TIMP metallopeptidase inhibitor 2 0.894346
TLR3 toll-like receptor 3 0.883744
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide 0.883744
PSORS1C1 psoriasis susceptibility 1 candidate 1 0.879512
PRG4 proteoglycan 4 0.868951
CD44 CD44 molecule (Indian blood group) 0.864734
KAT5 K(lysine) acetyltransferase 5 0.852106
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 0.843706
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 0.842447
MIPOL1 mirror-image polydactyly 1 0.816486
PTGES prostaglandin E synthase 0.810638
CXCL12 chemokine (C-X-C motif) ligand 12 0.807299
SUMO1 small ubiquitin-like modifier 1 0.793959
CTSK cathepsin K 0.78522
MMP10 matrix metallopeptidase 10 0.784804
MIR146A microRNA 146a 0.784388
FGF2 fibroblast growth factor 2 (basic) 0.784388
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.776079
EGR1 early growth response 1 0.768197
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.767783
DDR2 discoidin domain receptor tyrosine kinase 2 0.767368
SAA2 serum amyloid A2 0.760328
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.757018
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.754537
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.747515
MXRA5 matrix-remodelling associated 5 0.746277
CCL20 chemokine (C-C motif) ligand 20 0.745451
WDFY3 WD repeat and FYVE domain containing 3 0.734735
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.731854
PLAU plasminogen activator, urokinase 0.721988
IL4 interleukin 4 0.720755
CTSS cathepsin S 0.689226
TIMP3 TIMP metallopeptidase inhibitor 3 0.687592
IRAK1 interleukin-1 receptor-associated kinase 1 0.683511
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 0.675765
E2F2 E2F transcription factor 2 0.66925
CXCL5 chemokine (C-X-C motif) ligand 5 0.668843
IL32 interleukin 32 0.666809
IL18 interleukin 18 0.661929
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.657054
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.652183
CTGF connective tissue growth factor 0.651371
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.649344
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 0.644884
MMP8 matrix metallopeptidase 8 0.637999
KIF12 kinesin family member 12 0.631527
PLA2G10 phospholipase A2, group X 0.631527
IL33 interleukin 33 0.630718
CD4 CD4 molecule 0.623446
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 0.610541
PPARG peroxisome proliferator-activated receptor gamma 0.601283
WISP1 WNT1 inducible signaling pathway protein 1 0.598871
PLA2G1B phospholipase A2, group IB (pancreas) 0.593247
CCL5 chemokine (C-C motif) ligand 5 0.585224
SAA1 serum amyloid A1 0.574816
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 0.572418
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.560449
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.558059
TINAGL1 tubulointerstitial nephritis antigen-like 1 0.551695
IL23A interleukin 23, alpha subunit p19 0.547326
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 0.545342
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.542566
SENP1 SUMO1/sentrin specific peptidase 1 0.533856
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4 0.53267
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.52635
CFDP1 craniofacial development protein 1 0.522011
MEFV Mediterranean fever 0.522011
ANXA5 annexin A5 0.516891
CD58 CD58 molecule 0.516104
FOS FBJ murine osteosarcoma viral oncogene homolog 0.509027
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.508635
CXCL6 chemokine (C-X-C motif) ligand 6 0.505887
ANGPTL5 angiopoietin-like 5 0.500398
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.499615
IL16 interleukin 16 0.499615
SAT1 spermidine/spermine N1-acetyltransferase 1 0.499223
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.490619
HMGB1 high mobility group box 1 0.489838
CCL13 chemokine (C-C motif) ligand 13 0.488667
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.483596
VASH1 vasohibin 1 0.475034
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase 0.473869
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 0.473092
PADI2 peptidyl arginine deiminase, type II 0.469599
CCL3 chemokine (C-C motif) ligand 3 0.46766
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) 0.4634
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.462626
PMF1 polyamine-modulated factor 1 0.460305
CXCL2 chemokine (C-X-C motif) ligand 2 0.4576
SEBOX SEBOX homeobox 0.45374
CTSB cathepsin B 0.452198
GPD1L glycerol-3-phosphate dehydrogenase 1-like 0.449116
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.449116
IL22RA1 interleukin 22 receptor, alpha 1 0.448346
IFNL1 interferon, lambda 1 0.445653
ACPP acid phosphatase, prostate 0.44181
CX3CL1 chemokine (C-X3-C motif) ligand 1 0.43989
ADIPOR1 adiponectin receptor 1 0.439507
ANGPT1 angiopoietin 1 0.439507
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.438739
CD40 CD40 molecule, TNF receptor superfamily member 5 0.436438
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.432991
TOLLIP toll interacting protein 0.430312
HYAL1 hyaluronoglucosaminidase 1 0.42993
CCR6 chemokine (C-C motif) receptor 6 0.428018
ITGA6 integrin, alpha 6 0.42649
ADAM15 ADAM metallopeptidase domain 15 0.424581
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 0.424199
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.423818
IRF9 interferon regulatory factor 9 0.422292
IL10 interleukin 10 0.420766
VEGFA vascular endothelial growth factor A 0.415053
C8B complement component 8, beta polypeptide 0.411251
S100A4 S100 calcium binding protein A4 0.405555
TADA1 transcriptional adaptor 1 0.401386
IER2 immediate early response 2 0.398357
CARD17 caspase recruitment domain family, member 17 0.396087
MMP7 matrix metallopeptidase 7 0.394197
CD40LG CD40 ligand 0.393064
HDAC9 histone deacetylase 9 0.391931
MAPK14 mitogen-activated protein kinase 14 0.391931
IL11 interleukin 11 0.391176
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 0.391176
CEMIP cell migration inducing protein, hyaluronan binding 0.390799
SKIL SKI-like proto-oncogene 0.390044
CHUK conserved helix-loop-helix ubiquitous kinase 0.389666
CTF1 cardiotrophin 1 0.389289
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 0.387404
KNG1 kininogen 1 0.386273
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.382884
IL22 interleukin 22 0.373868
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 0.371245
SMAD2 SMAD family member 2 0.369747
CXCR3 chemokine (C-X-C motif) receptor 3 0.367876
NBPF8 neuroblastoma breakpoint family, member 8 0.363766
IL18BP interleukin 18 binding protein 0.363393
CTSL cathepsin L 0.361901
HYAL2 hyaluronoglucosaminidase 2 0.360036
OPTC opticin 0.356314
LOXL3 lysyl oxidase-like 3 0.355198
FASLG Fas ligand (TNF superfamily, member 6) 0.354084
MAP2K3 mitogen-activated protein kinase kinase 3 0.353712
TP53 tumor protein p53 0.35334
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 0.352969
TGFBR1 transforming growth factor, beta receptor 1 0.351114
IL15 interleukin 15 0.34926
CAPN8 calpain 8 0.348889
CXCL16 chemokine (C-X-C motif) ligand 16 0.345743
IL1R1 interleukin 1 receptor, type I 0.342602
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.340388
PPARA peroxisome proliferator-activated receptor alpha 0.334865
BMPR1A bone morphogenetic protein receptor, type IA 0.334498
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.33413
PDGFD platelet derived growth factor D 0.33413
IL6R interleukin 6 receptor 0.328994
CXCR6 chemokine (C-X-C motif) receptor 6 0.326615
ADIPOR2 adiponectin receptor 2 0.325701
CXCL10 chemokine (C-X-C motif) ligand 10 0.324239
TP53AIP1 tumor protein p53 regulated apoptosis inducing protein 1 0.322779
DPP4 dipeptidyl-peptidase 4 0.322779
PARP1 poly (ADP-ribose) polymerase 1 0.322414
MYD88 myeloid differentiation primary response 88 0.32205
UGDH UDP-glucose 6-dehydrogenase 0.321685
CCL8 chemokine (C-C motif) ligand 8 0.319863
MATN3 matrilin 3 0.319863
BGN biglycan 0.315498
PDGFB platelet-derived growth factor beta polypeptide 0.314409
ETV4 ets variant 4 0.314409
THY1 Thy-1 cell surface antigen 0.31187
COL1A1 collagen, type I, alpha 1 0.311145
IL13 interleukin 13 0.309697
JAK2 Janus kinase 2 0.307889
CXCL9 chemokine (C-X-C motif) ligand 9 0.306444
HAS1 hyaluronan synthase 1 0.304279
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.303198
IL19 interleukin 19 0.302118
MIR223 microRNA 223 0.299242
HAS3 hyaluronan synthase 3 0.297806
FBXO3 F-box protein 3 0.291543
FGF1 fibroblast growth factor 1 (acidic) 0.291008
CLCF1 cardiotrophin-like cytokine factor 1 0.291008
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 0.288158
MAPK11 mitogen-activated protein kinase 11 0.28213
CXCL11 chemokine (C-X-C motif) ligand 11 0.279659
ANGPT4 angiopoietin 4 0.277549
ADORA2A adenosine A2a receptor 0.277549
ANGPTL7 angiopoietin-like 7 0.273696
TREX1 three prime repair exonuclease 1 0.268828
MBOAT2 membrane bound O-acyltransferase domain containing 2 0.267446
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.267102
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.265725
IL34 interleukin 34 0.264696
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.262645
THBS2 thrombospondin 2 0.260267
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.259591
KLK11 kallikrein-related peptidase 11 0.257237
ANPEP alanyl (membrane) aminopeptidase 0.257237
ANGPTL1 angiopoietin-like 1 0.257237
TGFB2 transforming growth factor, beta 2 0.257237
IL2RA interleukin 2 receptor, alpha 0.255733
PRELP proline/arginine-rich end leucine-rich repeat protein 0.255567
TIMP4 TIMP metallopeptidase inhibitor 4 0.253908
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 0.251606
MAPK13 mitogen-activated protein kinase 13 0.250301
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.250301
PANX3 pannexin 3 0.242672
COL2A1 collagen, type II, alpha 1 0.241438
LGALS3 lectin, galactoside-binding, soluble, 3 0.238406
CXCL13 chemokine (C-X-C motif) ligand 13 0.236627
S100A12 S100 calcium binding protein A12 0.234302
AGER advanced glycosylation end product-specific receptor 0.23176
IL17RB interleukin 17 receptor B 0.231206
TNC tenascin C 0.229299
ELANE elastase, neutrophil expressed 0.229299
TENM1 teneurin transmembrane protein 1 0.228764
IL17RA interleukin 17 receptor A 0.227186
TTC34 tetratricopeptide repeat domain 34 0.225647
UNC5A unc-5 homolog A (C. elegans) 0.225144
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 0.224398
IL2 interleukin 2 0.22415
SLC25A19 solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19 0.223541
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2 0.222938
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 0.222699
CASP4 caspase 4, apoptosis-related cysteine peptidase 0.221755
SPRED1 sprouty-related, EVH1 domain containing 1 0.220378
TLR9 toll-like receptor 9 0.220378
IRX1 iroquois homeobox 1 0.220378
SH3RF1 SH3 domain containing ring finger 1 0.219596
SYVN1 synovial apoptosis inhibitor 1, synoviolin 0.218613
ANGPTL2 angiopoietin-like 2 0.21673
VIL1 villin 1 0.21573
CRP C-reactive protein, pentraxin-related 0.215534
HTRA1 HtrA serine peptidase 1 0.215341
CSF1 colony stimulating factor 1 (macrophage) 0.215147
HDAC4 histone deacetylase 4 0.214765
LIFR leukemia inhibitory factor receptor alpha 0.214765
IRAK2 interleukin-1 receptor-associated kinase 2 0.214576
CTSD cathepsin D 0.214576
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 0.214576
NAMPT nicotinamide phosphoribosyltransferase 0.214388
SNX9 sorting nexin 9 0.21365
TAC1 tachykinin, precursor 1 0.213291
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.213112
DBP D site of albumin promoter (albumin D-box) binding protein 0.212586
PHB2 prohibitin 2 0.209609
CCRL2 chemokine (C-C motif) receptor-like 2 0.209242
FLT3LG fms-related tyrosine kinase 3 ligand 0.208671
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 0.20322
CHAD chondroadherin 0.198815
CCDC34 coiled-coil domain containing 34 0.198491
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit 0.198478
C1QA complement component 1, q subcomponent, A chain 0.198272
CDSN corneodesmosin 0.19739
TRAF3 TNF receptor-associated factor 3 0.197369
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila) 0.196983
SMS spermine synthase 0.196934
IRF3 interferon regulatory factor 3 0.196924
CD163 CD163 molecule 0.196816
IRAK4 interleukin-1 receptor-associated kinase 4 0.196708
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.19644
C5AR1 complement component 5a receptor 1 0.196126
ADAM10 ADAM metallopeptidase domain 10 0.195876
IL10RA interleukin 10 receptor, alpha 0.195497
PPIA peptidylprolyl isomerase A (cyclophilin A) 0.195294
PSAT1 phosphoserine aminotransferase 1 0.195145
DYNLRB1 dynein, light chain, roadblock-type 1 0.195063
CLEC1B C-type lectin domain family 1, member B 0.194981
CD80 CD80 molecule 0.194933
RIPK2 receptor-interacting serine-threonine kinase 2 0.194789
HIST1H1B histone cluster 1, H1b 0.194789
C5 complement component 5 0.194752
SUMO3 small ubiquitin-like modifier 3 0.194579
ICOSLG inducible T-cell co-stimulator ligand 0.194466
BMX BMX non-receptor tyrosine kinase 0.194352
CD69 CD69 molecule 0.194287
A2M alpha-2-macroglobulin 0.194261
S100A8 S100 calcium binding protein A8 0.194248
MAPK9 mitogen-activated protein kinase 9 0.194011
IL5 interleukin 5 0.193957
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 0.193876
SUMO2 small ubiquitin-like modifier 2 0.193614
CCR1 chemokine (C-C motif) receptor 1 0.193344
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy 0.193315
CD200R1 CD200 receptor 1 0.192777
S100A9 S100 calcium binding protein A9 0.192528
COPS5 COP9 signalosome subunit 5 0.192481
SIRT6 sirtuin 6 0.192465
ADGRE5 adhesion G protein-coupled receptor E5 0.192224
HDAC11 histone deacetylase 11 0.19132
MST1 macrophage stimulating 1 0.191267
IGFBP7 insulin-like growth factor binding protein 7 0.191231
KLRG1 killer cell lectin-like receptor subfamily G, member 1 0.190734
BTK Bruton agammaglobulinemia tyrosine kinase 0.190427