suramin sodium-7524 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the suramin sodium-7524 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADARB1 adenosine deaminase, RNA-specific, B1
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AHSG alpha-2-HS-glycoprotein
AQP3 aquaporin 3 (Gill blood group)
ARHGAP1 Rho GTPase activating protein 1
ARHGAP26 Rho GTPase activating protein 26
ARHGAP33 Rho GTPase activating protein 33
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
ATP9A ATPase, class II, type 9A
C14ORF93 chromosome 14 open reading frame 93
C21ORF2 chromosome 21 open reading frame 2
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CAPRIN2 caprin family member 2
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCNK cyclin K
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CDC5L cell division cycle 5-like
CEP290 centrosomal protein 290kDa
CLIP2 CAP-GLY domain containing linker protein 2
COX11 COX11 cytochrome c oxidase copper chaperone
CRYBG3 beta-gamma crystallin domain containing 3
CTRC chymotrypsin C (caldecrin)
CYLD cylindromatosis (turban tumor syndrome)
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DAZL deleted in azoospermia-like
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DGCR8 DGCR8 microprocessor complex subunit
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DRD2 dopamine receptor D2
DUSP2 dual specificity phosphatase 2
DVL2 dishevelled segment polarity protein 2
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FBLN1 fibulin 1
GLP1R glucagon-like peptide 1 receptor
GPR143 G protein-coupled receptor 143
GRB10 growth factor receptor-bound protein 10
HIST1H4D histone cluster 1, H4d
HMHA1 histocompatibility (minor) HA-1
HOXD1 homeobox D1
KIAA0586 KIAA0586
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
LOC390998 ribosomal protein L10 pseudogene
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MED16 mediator complex subunit 16
MINK1 misshapen-like kinase 1
MMP17 matrix metallopeptidase 17 (membrane-inserted)
NFIB nuclear factor I/B
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NR5A2 nuclear receptor subfamily 5, group A, member 2
NRSN2 neurensin 2
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PCDHGA10 protocadherin gamma subfamily A, 10
PIDD1 p53-induced death domain protein 1
PLAGL1 pleiomorphic adenoma gene-like 1
PLK3 polo-like kinase 3
PLXNA1 plexin A1
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
RAB35 RAB35, member RAS oncogene family
RASAL1 RAS protein activator like 1 (GAP1 like)
RASAL2 RAS protein activator like 2
RBP4 retinol binding protein 4, plasma
RGS11 regulator of G-protein signaling 11
RNASEH2B ribonuclease H2, subunit B
RNF19B ring finger protein 19B
RNF8 ring finger protein 8, E3 ubiquitin protein ligase
SAFB2 scaffold attachment factor B2
SATB2 SATB homeobox 2
SCAF4 SR-related CTD-associated factor 4
SCARB2 scavenger receptor class B, member 2
SECTM1 secreted and transmembrane 1
SERGEF secretion regulating guanine nucleotide exchange factor
SFTPB surfactant protein B
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SPHK2 sphingosine kinase 2
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SPRY2 sprouty homolog 2 (Drosophila)
SRSF1 serine/arginine-rich splicing factor 1
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STIM1 stromal interaction molecule 1
SYT11 synaptotagmin XI
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TBC1D2 TBC1 domain family, member 2
TMEM209 transmembrane protein 209
TMOD1 tropomodulin 1
TPK1 thiamin pyrophosphokinase 1
TPP1 tripeptidyl peptidase I
TRIM14 tripartite motif containing 14
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
VPRBP Vpr (HIV-1) binding protein
ZC3H13 zinc finger CCCH-type containing 13
ZKSCAN5 zinc finger with KRAB and SCAN domains 5
ZNF589 zinc finger protein 589
ZNF665 zinc finger protein 665
ZNF76 zinc finger protein 76
ZNF783 zinc finger family member 783

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ACTL8 actin-like 8
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ALS2CL ALS2 C-terminal like
ANKFY1 ankyrin repeat and FYVE domain containing 1
APLP1 amyloid beta (A4) precursor-like protein 1
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ASPHD1 aspartate beta-hydroxylase domain containing 1
BGLAP bone gamma-carboxyglutamate (gla) protein
BTNL3 butyrophilin-like 3
C11ORF30 chromosome 11 open reading frame 30
C1QB complement component 1, q subcomponent, B chain
C1QTNF3 C1q and tumor necrosis factor related protein 3
CAMKMT calmodulin-lysine N-methyltransferase
CCDC71 coiled-coil domain containing 71
CD79B CD79b molecule, immunoglobulin-associated beta
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CLDN15 claudin 15
DGAT1 diacylglycerol O-acyltransferase 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DPY19L1P1 DPY19L1 pseudogene 1
DYSF dysferlin
EIF5A2 eukaryotic translation initiation factor 5A2
ERO1L ERO1-like (S. cerevisiae)
F3 coagulation factor III (thromboplastin, tissue factor)
FAM110B family with sequence similarity 110, member B
FANCC Fanconi anemia, complementation group C
FBXO22 F-box protein 22
FOXF2 forkhead box F2
GADD45A growth arrest and DNA-damage-inducible, alpha
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HIST1H2AE histone cluster 1, H2ae
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BM histone cluster 1, H2bm
HIST1H4A histone cluster 1, H4a
HLA-DMA major histocompatibility complex, class II, DM alpha
HOXA6 homeobox A6
IRF1 interferon regulatory factor 1
IRF2 interferon regulatory factor 2
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KLHL21 kelch-like family member 21
KRT15 keratin 15, type I
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LINC00597 long intergenic non-protein coding RNA 597
LMTK2 lemur tyrosine kinase 2
LOC100131510 uncharacterized LOC100131510
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MORC3 MORC family CW-type zinc finger 3
MTERF4 mitochondrial transcription termination factor 4
MYL5 myosin, light chain 5, regulatory
N4BP3 NEDD4 binding protein 3
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NNAT neuronatin
NOD1 nucleotide-binding oligomerization domain containing 1
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OR2H1 olfactory receptor, family 2, subfamily H, member 1
PCDHB13 protocadherin beta 13
PCDHB8 protocadherin beta 8
PCDHGA8 protocadherin gamma subfamily A, 8
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
PLTP phospholipid transfer protein
PRPH peripherin
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
RFX7 regulatory factor X, 7
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPAP2 RNA polymerase II associated protein 2
S100A4 S100 calcium binding protein A4
SDC3 syndecan 3
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SLPI secretory leukocyte peptidase inhibitor
SRD5A3 steroid 5 alpha-reductase 3
SSFA2 sperm specific antigen 2
ST5 suppression of tumorigenicity 5
STAB2 stabilin 2
STARD5 StAR-related lipid transfer (START) domain containing 5
TCP10L t-complex 10-like
TDRD1 tudor domain containing 1
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRAF2 TNF receptor-associated factor 2
TTC30A tetratricopeptide repeat domain 30A
UPK3B uroplakin 3B
VLDLR very low density lipoprotein receptor
WDR33 WD repeat domain 33
ZNF254 zinc finger protein 254
ZNF286A zinc finger protein 286A
ZNF419 zinc finger protein 419
ZNF468 zinc finger protein 468
ZNF606 zinc finger protein 606