suloctidil-2651 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the suloctidil-2651 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANXA1 annexin A1
AREG amphiregulin
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ATF3 activating transcription factor 3
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BHLHE40 basic helix-loop-helix family, member e40
BIRC3 baculoviral IAP repeat containing 3
CGA glycoprotein hormones, alpha polypeptide
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CTRL chymotrypsin-like
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DLX2 distal-less homeobox 2
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
DUSP4 dual specificity phosphatase 4
DUSP5 dual specificity phosphatase 5
DUSP6 dual specificity phosphatase 6
EFNA1 ephrin-A1
EGR1 early growth response 1
EGR3 early growth response 3
EGR4 early growth response 4
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOSL1 FOS-like antigen 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GEM GTP binding protein overexpressed in skeletal muscle
HBEGF heparin-binding EGF-like growth factor
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H2BC histone cluster 1, H2bc
HIST1H2BJ histone cluster 1, H2bj
HIST1H4H histone cluster 1, H4h
HMOX1 heme oxygenase 1
ICAM1 intercellular adhesion molecule 1
IER2 immediate early response 2
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
INHBE inhibin, beta E
INSIG1 insulin induced gene 1
IRF1 interferon regulatory factor 1
IRF8 interferon regulatory factor 8
IRS2 insulin receptor substrate 2
ISG20 interferon stimulated exonuclease gene 20kDa
ITCH itchy E3 ubiquitin protein ligase
JUN jun proto-oncogene
JUNB jun B proto-oncogene
KLF10 Kruppel-like factor 10
KLF2 Kruppel-like factor 2
KLF6 Kruppel-like factor 6
KLHL24 kelch-like family member 24
LIF leukemia inhibitory factor
LPIN1 lipin 1
LTB lymphotoxin beta (TNF superfamily, member 3)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MBNL2 muscleblind-like splicing regulator 2
MIR22HG MIR22 host gene
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MT2A metallothionein 2A
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NFIL3 nuclear factor, interleukin 3 regulated
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
PDE4DIP phosphodiesterase 4D interacting protein
PER1 period circadian clock 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
RCAN1 regulator of calcineurin 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RND1 Rho family GTPase 1
RSL1D1 ribosomal L1 domain containing 1
SAMD9 sterile alpha motif domain containing 9
SAT1 spermidine/spermine N1-acetyltransferase 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLCO4C1 solute carrier organic anion transporter family, member 4C1
SNW1 SNW domain containing 1
SOX9 SRY (sex determining region Y)-box 9
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TFPI2 tissue factor pathway inhibitor 2
TLR2 toll-like receptor 2
TMEM53 transmembrane protein 53
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRIB1 tribbles pseudokinase 1
TRIB3 tribbles pseudokinase 3
TRIM2 tripartite motif containing 2
VEGFA vascular endothelial growth factor A
WDR59 WD repeat domain 59
ZFP36 ZFP36 ring finger protein
ZNF165 zinc finger protein 165
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADGRA3 adhesion G protein-coupled receptor A3
ARL15 ADP-ribosylation factor-like 15
ASB9 ankyrin repeat and SOCS box containing 9
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATP13A2 ATPase type 13A2
BCORL1 BCL6 corepressor-like 1
BIRC7 baculoviral IAP repeat containing 7
BMP4 bone morphogenetic protein 4
C17ORF70 chromosome 17 open reading frame 70
C22ORF46 chromosome 22 open reading frame 46
C5AR2 complement component 5a receptor 2
C9ORF40 chromosome 9 open reading frame 40
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC15 coiled-coil domain containing 15
CDK20 cyclin-dependent kinase 20
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHKB choline kinase beta
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CRYBG3 beta-gamma crystallin domain containing 3
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EGFL7 EGF-like-domain, multiple 7
EGLN3 egl-9 family hypoxia-inducible factor 3
ERCC4 excision repair cross-complementation group 4
ERCC5 excision repair cross-complementation group 5
ERN2 endoplasmic reticulum to nucleus signaling 2
EXO5 exonuclease 5
FAM86C1 family with sequence similarity 86, member C1
FMOD fibromodulin
FPGT fucose-1-phosphate guanylyltransferase
FUZ fuzzy planar cell polarity protein
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GHR growth hormone receptor
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GPR19 G protein-coupled receptor 19
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HOXC13 homeobox C13
IFI35 interferon-induced protein 35
IGFLR1 IGF-like family receptor 1
IGSF3 immunoglobulin superfamily, member 3
IMPACT impact RWD domain protein
IPO8 importin 8
JMJD4 jumonji domain containing 4
KCTD15 potassium channel tetramerization domain containing 15
KIF13B kinesin family member 13B
LAMB3 laminin, beta 3
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LYRM9 LYR motif containing 9
MAST3 microtubule associated serine/threonine kinase 3
MCM9 minichromosome maintenance complex component 9
MSMB microseminoprotein, beta-
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NBEAL2 neurobeachin-like 2
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NEK11 NIMA-related kinase 11
NIPAL2 NIPA-like domain containing 2
NKX3-2 NK3 homeobox 2
NRSN2 neurensin 2
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OLFML2A olfactomedin-like 2A
OSGEP O-sialoglycoprotein endopeptidase
PARD6A par-6 family cell polarity regulator alpha
PCOLCE2 procollagen C-endopeptidase enhancer 2
PEX26 peroxisomal biogenesis factor 26
PFAS phosphoribosylformylglycinamidine synthase
PHEX phosphate regulating endopeptidase homolog, X-linked
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PMCH pro-melanin-concentrating hormone
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PPT2 palmitoyl-protein thioesterase 2
PROCR protein C receptor, endothelial
PRR15L proline rich 15-like
RBL1 retinoblastoma-like 1
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RPL13P5 ribosomal protein L13 pseudogene 5
SCN1B sodium channel, voltage gated, type I beta subunit
SFT2D2 SFT2 domain containing 2
SLC16A6 solute carrier family 16, member 6
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC46A3 solute carrier family 46, member 3
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SOX3 SRY (sex determining region Y)-box 3
SPINK5 serine peptidase inhibitor, Kazal type 5
TCHH trichohyalin
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TRAF5 TNF receptor-associated factor 5
TRIM25 tripartite motif containing 25
TTLL1 tubulin tyrosine ligase-like family member 1
USB1 U6 snRNA biogenesis 1
WLS wntless Wnt ligand secretion mediator
ZDHHC18 zinc finger, DHHC-type containing 18
ZNF573 zinc finger protein 573