sulindac-307 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the sulindac-307 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
AKAP13 A kinase (PRKA) anchor protein 13
AMT aminomethyltransferase
APOLD1 apolipoprotein L domain containing 1
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BMP6 bone morphogenetic protein 6
CA1 carbonic anhydrase I
CALU calumenin
CCDC53 coiled-coil domain containing 53
CDC16 cell division cycle 16
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CNOT8 CCR4-NOT transcription complex, subunit 8
CORO1B coronin, actin binding protein, 1B
CTAGE9 CTAGE family, member 9
DDAH2 dimethylarginine dimethylaminohydrolase 2
DENND3 DENN/MADD domain containing 3
DIO2 deiodinase, iodothyronine, type II
DNAH3 dynein, axonemal, heavy chain 3
DND1 DND microRNA-mediated repression inhibitor 1
ELF4 E74-like factor 4 (ets domain transcription factor)
EPS8L1 EPS8-like 1
EXOC3 exocyst complex component 3
FAM89B family with sequence similarity 89, member B
FKBP2 FK506 binding protein 2, 13kDa
FOXC1 forkhead box C1
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GPR107 G protein-coupled receptor 107
HHIPL2 HHIP-like 2
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HMGXB3 HMG box domain containing 3
HPX hemopexin
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IGFBP3 insulin-like growth factor binding protein 3
IRGQ immunity-related GTPase family, Q
ITGA6 integrin, alpha 6
JOSD1 Josephin domain containing 1
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1
KIF18A kinesin family member 18A
KRT8P12 keratin 8 pseudogene 12
LDLR low density lipoprotein receptor
LDLRAP1 low density lipoprotein receptor adaptor protein 1
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
LINC00574 long intergenic non-protein coding RNA 574
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LPPR2 lipid phosphate phosphatase-related protein type 2
LTBP1 latent transforming growth factor beta binding protein 1
MARC1 mitochondrial amidoxime reducing component 1
MEF2A myocyte enhancer factor 2A
MIPEP mitochondrial intermediate peptidase
MOGAT2 monoacylglycerol O-acyltransferase 2
MST1 macrophage stimulating 1
MTERF4 mitochondrial transcription termination factor 4
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NUP160 nucleoporin 160kDa
OR7A17 olfactory receptor, family 7, subfamily A, member 17
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PCDH1 protocadherin 1
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PLCD1 phospholipase C, delta 1
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein
PPME1 protein phosphatase methylesterase 1
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
PTPN7 protein tyrosine phosphatase, non-receptor type 7
PXN paxillin
PYROXD1 pyridine nucleotide-disulphide oxidoreductase domain 1
QTRT1 queuine tRNA-ribosyltransferase 1
RAB28 RAB28, member RAS oncogene family
RNF220 ring finger protein 220
RRBP1 ribosome binding protein 1
RRP15 ribosomal RNA processing 15 homolog (S. cerevisiae)
RUNDC3A RUN domain containing 3A
SCAMP4 secretory carrier membrane protein 4
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SIAH1 siah E3 ubiquitin protein ligase 1
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SPON2 spondin 2, extracellular matrix protein
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SQRDL sulfide quinone reductase-like (yeast)
STX5 syntaxin 5
TBPL1 TBP-like 1
THTPA thiamine triphosphatase
TM2D1 TM2 domain containing 1
TMEM161A transmembrane protein 161A
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TNS2 tensin 2
TOR1AIP1 torsin A interacting protein 1
TSPYL2 TSPY-like 2
USP24 ubiquitin specific peptidase 24
VIPR1 vasoactive intestinal peptide receptor 1
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WIZ widely interspaced zinc finger motifs
ZBTB40 zinc finger and BTB domain containing 40
ZDHHC3 zinc finger, DHHC-type containing 3
ZNF500 zinc finger protein 500

decreased expression

Symbol Name
ADM2 adrenomedullin 2
AIM2 absent in melanoma 2
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C1QTNF1 C1q and tumor necrosis factor related protein 1
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C7ORF43 chromosome 7 open reading frame 43
CA14 carbonic anhydrase XIV
CAV3 caveolin 3
CD3D CD3d molecule, delta (CD3-TCR complex)
CD82 CD82 molecule
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CFAP70 cilia and flagella associated protein 70
CFAP74 cilia and flagella associated protein 74
CHRM4 cholinergic receptor, muscarinic 4
CLCA1 chloride channel accessory 1
CRBN cereblon
CTLA4 cytotoxic T-lymphocyte-associated protein 4
DCSTAMP dendrocyte expressed seven transmembrane protein
DHRS9 dehydrogenase/reductase (SDR family) member 9
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EGFL6 EGF-like-domain, multiple 6
ELP6 elongator acetyltransferase complex subunit 6
EVX1 even-skipped homeobox 1
FAM153A family with sequence similarity 153, member A
FAM188A family with sequence similarity 188, member A
FOXC2 forkhead box C2
GAB2 GRB2-associated binding protein 2
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45G growth arrest and DNA-damage-inducible, gamma
GCKR glucokinase (hexokinase 4) regulator
GLI3 GLI family zinc finger 3
GLMN glomulin, FKBP associated protein
GLT8D2 glycosyltransferase 8 domain containing 2
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
LCN2 lipocalin 2
LENEP lens epithelial protein
LINC00216 long intergenic non-protein coding RNA 216
LMTK2 lemur tyrosine kinase 2
LOC729164 hCG1732469
LRRC20 leucine rich repeat containing 20
MAGEA3 melanoma antigen family A3
MMP8 matrix metallopeptidase 8
MNT MAX network transcriptional repressor
MTMR10 myotubularin related protein 10
NLK nemo-like kinase
NNAT neuronatin
NRSN2 neurensin 2
NUPL2 nucleoporin like 2
OLFML1 olfactomedin-like 1
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic)
PADI1 peptidyl arginine deiminase, type I
PIEZO2 piezo-type mechanosensitive ion channel component 2
PIGK phosphatidylinositol glycan anchor biosynthesis, class K
PLEK2 pleckstrin 2
POU3F3 POU class 3 homeobox 3
PRDM11 PR domain containing 11
PRKCE protein kinase C, epsilon
PRPF19 pre-mRNA processing factor 19
PSG7 pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene)
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
REG1A regenerating islet-derived 1 alpha
RGS17 regulator of G-protein signaling 17
RHOH ras homolog family member H
RNF141 ring finger protein 141
RNF208 ring finger protein 208
RUFY2 RUN and FYVE domain containing 2
SAG S-antigen; retina and pineal gland (arrestin)
SETD1A SET domain containing 1A
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLC38A3 solute carrier family 38, member 3
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SPTBN5 spectrin, beta, non-erythrocytic 5
STAT5A signal transducer and activator of transcription 5A
STMN4 stathmin-like 4
SUSD4 sushi domain containing 4
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TGM5 transglutaminase 5
TLN1 talin 1
TMEM176A transmembrane protein 176A
TNNI3 troponin I type 3 (cardiac)
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
USP48 ubiquitin specific peptidase 48
VSIG10 V-set and immunoglobulin domain containing 10
WNT2 wingless-type MMTV integration site family member 2
ZFP36 ZFP36 ring finger protein
ZFR2 zinc finger RNA binding protein 2
ZIC1 Zic family member 1
ZNF394 zinc finger protein 394
ZNF528 zinc finger protein 528
ZNHIT2 zinc finger, HIT-type containing 2
ZXDC ZXD family zinc finger C