sulfinpyrazone-6230 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the sulfinpyrazone-6230 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
AKT3 v-akt murine thymoma viral oncogene homolog 3
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
ARID1A AT rich interactive domain 1A (SWI-like)
ASPHD1 aspartate beta-hydroxylase domain containing 1
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide
BMP2K BMP2 inducible kinase
BMP4 bone morphogenetic protein 4
BTN2A1 butyrophilin, subfamily 2, member A1
C11ORF80 chromosome 11 open reading frame 80
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C8ORF60 chromosome 8 open reading frame 60
CACTIN cactin, spliceosome C complex subunit
CCNO cyclin O
CGA glycoprotein hormones, alpha polypeptide
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
COL8A1 collagen, type VIII, alpha 1
CRYGC crystallin, gamma C
CXCR2 chemokine (C-X-C motif) receptor 2
CYLD cylindromatosis (turban tumor syndrome)
DAAM2 dishevelled associated activator of morphogenesis 2
DIEXF digestive organ expansion factor homolog (zebrafish)
DVL2 dishevelled segment polarity protein 2
ECE1 endothelin converting enzyme 1
EVA1B eva-1 homolog B (C. elegans)
FGD6 FYVE, RhoGEF and PH domain containing 6
FZD10 frizzled class receptor 10
GADD45G growth arrest and DNA-damage-inducible, gamma
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GH1 growth hormone 1
GLS glutaminase
GRB10 growth factor receptor-bound protein 10
GRM7 glutamate receptor, metabotropic 7
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
IGHA1 immunoglobulin heavy constant alpha 1
IGL immunoglobulin lambda locus
IKZF1 IKAROS family zinc finger 1 (Ikaros)
ING1 inhibitor of growth family, member 1
IQCK IQ motif containing K
ITGA8 integrin, alpha 8
KDM8 lysine (K)-specific demethylase 8
KERA keratocan
KHK ketohexokinase (fructokinase)
KLHL25 kelch-like family member 25
LY86 lymphocyte antigen 86
MAGEA1 melanoma antigen family A1
MBNL2 muscleblind-like splicing regulator 2
MCOLN1 mucolipin 1
MFAP3L microfibrillar-associated protein 3-like
MID1 midline 1
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MTAP methylthioadenosine phosphorylase
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NCOR2 nuclear receptor corepressor 2
NEK11 NIMA-related kinase 11
NUP214 nucleoporin 214kDa
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PCM1 pericentriolar material 1
PDE10A phosphodiesterase 10A
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PGAP1 post-GPI attachment to proteins 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCH1 phospholipase C, eta 1
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PRDX2 peroxiredoxin 2
PRF1 perforin 1 (pore forming protein)
PYCRL pyrroline-5-carboxylate reductase-like
R3HCC1L R3H domain and coiled-coil containing 1-like
RASA3 RAS p21 protein activator 3
RCAN3 RCAN family member 3
RCE1 Ras converting CAAX endopeptidase 1
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
STIM1 stromal interaction molecule 1
SUGP1 SURP and G patch domain containing 1
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SYBU syntabulin (syntaxin-interacting)
TMEM161A transmembrane protein 161A
TMEM209 transmembrane protein 209
TMEM63A transmembrane protein 63A
TMPRSS2 transmembrane protease, serine 2
TRABD TraB domain containing
TREM2 triggering receptor expressed on myeloid cells 2
UBQLN4 ubiquilin 4
UBXN1 UBX domain protein 1
VPRBP Vpr (HIV-1) binding protein
WDR48 WD repeat domain 48
WIZ widely interspaced zinc finger motifs
WNT16 wingless-type MMTV integration site family, member 16
WWTR1 WW domain containing transcription regulator 1
ZBTB43 zinc finger and BTB domain containing 43
ZC3H13 zinc finger CCCH-type containing 13
ZNF444 zinc finger protein 444
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
AHDC1 AT hook, DNA binding motif, containing 1
ANKZF1 ankyrin repeat and zinc finger domain containing 1
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BBC3 BCL2 binding component 3
BBS1 Bardet-Biedl syndrome 1
BTF3P11 basic transcription factor 3 pseudogene 11
C11ORF57 chromosome 11 open reading frame 57
C22ORF29 chromosome 22 open reading frame 29
C2CD2 C2 calcium-dependent domain containing 2
C5ORF45 chromosome 5 open reading frame 45
CCDC85C coiled-coil domain containing 85C
CD320 CD320 molecule
CDKN2AIP CDKN2A interacting protein
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CPPED1 calcineurin-like phosphoesterase domain containing 1
CTAGE9 CTAGE family, member 9
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DHRS11 dehydrogenase/reductase (SDR family) member 11
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
ECHDC1 ethylmalonyl-CoA decarboxylase 1
ECI1 enoyl-CoA delta isomerase 1
ELP3 elongator acetyltransferase complex subunit 3
EML4 echinoderm microtubule associated protein like 4
ERCC5 excision repair cross-complementation group 5
EVPL envoplakin
FCHSD2 FCH and double SH3 domains 2
FKBP10 FK506 binding protein 10, 65 kDa
FKBPL FK506 binding protein like
FMO4 flavin containing monooxygenase 4
FOXA1 forkhead box A1
FRAT1 frequently rearranged in advanced T-cell lymphomas 1
GMEB1 glucocorticoid modulatory element binding protein 1
GUF1 GUF1 GTPase homolog (S. cerevisiae)
HAUS6 HAUS augmin-like complex, subunit 6
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HP1BP3 heterochromatin protein 1, binding protein 3
IL15RA interleukin 15 receptor, alpha
IL17RA interleukin 17 receptor A
INCENP inner centromere protein antigens 135/155kDa
JMJD1C jumonji domain containing 1C
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KCTD20 potassium channel tetramerization domain containing 20
KLHL12 kelch-like family member 12
LOC730101 uncharacterized LOC730101
LRP5L low density lipoprotein receptor-related protein 5-like
LRRC49 leucine rich repeat containing 49
MED9 mediator complex subunit 9
MORC3 MORC family CW-type zinc finger 3
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
NBAS neuroblastoma amplified sequence
NBEAL2 neurobeachin-like 2
NCAM2 neural cell adhesion molecule 2
NMRK1 nicotinamide riboside kinase 1
NR1D2 nuclear receptor subfamily 1, group D, member 2
NSUN3 NOP2/Sun domain family, member 3
ODF2 outer dense fiber of sperm tails 2
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PC pyruvate carboxylase
PGM1 phosphoglucomutase 1
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PRR7 proline rich 7 (synaptic)
PTBP2 polypyrimidine tract binding protein 2
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RASA2 RAS p21 protein activator 2
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF126P1 ring finger protein 126 pseudogene 1
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SCAI suppressor of cancer cell invasion
SCML1 sex comb on midleg-like 1 (Drosophila)
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SETD8 SET domain containing (lysine methyltransferase) 8
SKA1 spindle and kinetochore associated complex subunit 1
SLC16A6 solute carrier family 16, member 6
SLC25A40 solute carrier family 25, member 40
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SNUPN snurportin 1
SNX15 sorting nexin 15
SP140L SP140 nuclear body protein-like
STAG3 stromal antigen 3
TCTN1 tectonic family member 1
TEAD3 TEA domain family member 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMC7 transmembrane channel-like 7
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WDR18 WD repeat domain 18
ZNF189 zinc finger protein 189
ZNF211 zinc finger protein 211
ZNF408 zinc finger protein 408
ZNF83 zinc finger protein 83