stem cell maintenance Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description The process by which an organism or tissue maintains a population of stem cells of a single type. This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types. (Gene Ontology, GO_0019827)
External Link http://amigo.geneontology.org/amigo/term/GO:0019827
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Genes

134 genes participating in the stem cell maintenance biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
APC adenomatous polyposis coli
ASCL2 achaete-scute family bHLH transcription factor 2
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
BCL9 B-cell CLL/lymphoma 9
BCL9L B-cell CLL/lymphoma 9-like
BMPR1A bone morphogenetic protein receptor, type IA
BRAF B-Raf proto-oncogene, serine/threonine kinase
CDC73 cell division cycle 73
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDX2 caudal type homeobox 2
CREBBP CREB binding protein
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTR9 CTR9, Paf1/RNA polymerase II complex component
CUL4A cullin 4A
DICER1 dicer 1, ribonuclease type III
DIS3L2 DIS3 like 3'-5' exoribonuclease 2
DLL1 delta-like 1 (Drosophila)
DPPA2 developmental pluripotency associated 2
EOMES eomesodermin
EPAS1 endothelial PAS domain protein 1
EPHA1 EPH receptor A1
ESRRB estrogen-related receptor beta
FGF10 fibroblast growth factor 10
FGF2 fibroblast growth factor 2 (basic)
FGF4 fibroblast growth factor 4
FGFR3 fibroblast growth factor receptor 3
FOXD3 forkhead box D3
FOXO1 forkhead box O1
FOXO3 forkhead box O3
FUT10 fucosyltransferase 10 (alpha (1,3) fucosyltransferase)
FZD7 frizzled class receptor 7
GATA2 GATA binding protein 2
HES1 hes family bHLH transcription factor 1
HES5 hes family bHLH transcription factor 5
HOOK3 hook microtubule-tethering protein 3
JAG1 jagged 1
KAT6A K(lysine) acetyltransferase 6A
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF10 Kruppel-like factor 10
KLF4 Kruppel-like factor 4 (gut)
LDB1 LIM domain binding 1
LDB2 LIM domain binding 2
LEO1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
LIF leukemia inhibitory factor
LIG4 ligase IV, DNA, ATP-dependent
LIN28A lin-28 homolog A (C. elegans)
LRP5 low density lipoprotein receptor-related protein 5
MED10 mediator complex subunit 10
MED12 mediator complex subunit 12
MED14 mediator complex subunit 14
MED15 mediator complex subunit 15
MED17 mediator complex subunit 17
MED21 mediator complex subunit 21
MED24 mediator complex subunit 24
MED27 mediator complex subunit 27
MED28 mediator complex subunit 28
MED30 mediator complex subunit 30
MED7 mediator complex subunit 7
METTL14 methyltransferase like 14
METTL3 methyltransferase like 3
MMP24 matrix metallopeptidase 24 (membrane-inserted)
MTF2 metal response element binding transcription factor 2
NANOG Nanog homeobox
NANOS2 nanos homolog 2 (Drosophila)
NIPBL Nipped-B homolog (Drosophila)
NKAP NFKB activating protein
NODAL nodal growth differentiation factor
NOG noggin
NOTCH1 notch 1
NOTCH2 notch 2
NR2E1 nuclear receptor subfamily 2, group E, member 1
PADI4 peptidyl arginine deiminase, type IV
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
PBX1 pre-B-cell leukemia homeobox 1
PCM1 pericentriolar material 1
PIWIL2 piwi-like RNA-mediated gene silencing 2
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa
POLR2D polymerase (RNA) II (DNA directed) polypeptide D
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
POLR2F polymerase (RNA) II (DNA directed) polypeptide F
POLR2G polymerase (RNA) II (DNA directed) polypeptide G
POLR2H polymerase (RNA) II (DNA directed) polypeptide H
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
POU5F1 POU class 5 homeobox 1
PRDM14 PR domain containing 14
PRDM16 PR domain containing 16
PROX1 prospero homeobox 1
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RBPJ recombination signal binding protein for immunoglobulin kappa J region
RIF1 replication timing regulatory factor 1
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
SALL4 spalt-like transcription factor 4
SCT secretin
SETD1A SET domain containing 1A
SFRP1 secreted frizzled-related protein 1
SIX2 SIX homeobox 2
SKI SKI proto-oncogene
SMAD2 SMAD family member 2
SMAD4 SMAD family member 4
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMC1A structural maintenance of chromosomes 1A
SMC3 structural maintenance of chromosomes 3
SOX2 SRY (sex determining region Y)-box 2
SOX4 SRY (sex determining region Y)-box 4
SOX9 SRY (sex determining region Y)-box 9
SPI1 Spi-1 proto-oncogene
SRRT serrate, RNA effector molecule
SS18 synovial sarcoma translocation, chromosome 18
STAG2 stromal antigen 2
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TBX3 T-box 3
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TCL1A T-cell leukemia/lymphoma 1A
TDGF1 teratocarcinoma-derived growth factor 1
TET1 tet methylcytosine dioxygenase 1
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
VANGL2 VANGL planar cell polarity protein 2
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae)
WNT7A wingless-type MMTV integration site family, member 7A
WNT9B wingless-type MMTV integration site family, member 9B
YAP1 Yes-associated protein 1
ZCCHC11 zinc finger, CCHC domain containing 11
ZFP36L2 ZFP36 ring finger protein-like 2
ZHX2 zinc fingers and homeoboxes 2
ZIC3 Zic family member 3
ZNF358 zinc finger protein 358
ZSCAN10 zinc finger and SCAN domain containing 10