srp-dependent cotranslational protein targeting to membrane, translocation Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description The process during cotranslational membrane targeting wherein proteins move across a membrane. SRP and its receptor initiate the transfer of the nascent chain across the endoplasmic reticulum (ER) membrane; they then dissociate from the chain, which is transferred to a set of transmembrane proteins, collectively called the translocon. Once the nascent chain translocon complex is assembled, the elongating chain passes directly from the large ribosomal subunit into the centers of the translocon, a protein-lined channel within the membrane. The growing chain is never exposed to the cytosol and does not fold until it reaches the ER lumen. (Gene Ontology, GO_0006616)
External Link http://amigo.geneontology.org/amigo/term/GO:0006616
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Genes

2 genes participating in the srp-dependent cotranslational protein targeting to membrane, translocation biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
SRP54 signal recognition particle 54kDa
ZFAND2B zinc finger, AN1-type domain 2B