sphingosine-1-phosphate signaling pathway Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description A series of molecular signals initiated by the sphingolipid sphingosine-1-phosphate (S1P) binding to a receptor on the surface of the cell, and which proceeds with the activated receptor transmitting the signal by promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The pathway ends with regulation of a downstream cellular process, e.g. transcription. (Gene Ontology, GO_0003376)
External Link http://amigo.geneontology.org/amigo/term/GO:0003376
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Genes

9 genes participating in the sphingosine-1-phosphate signaling pathway biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
GPR6 G protein-coupled receptor 6
S1PR1 sphingosine-1-phosphate receptor 1
S1PR2 sphingosine-1-phosphate receptor 2
S1PR3 sphingosine-1-phosphate receptor 3
S1PR4 sphingosine-1-phosphate receptor 4
S1PR5 sphingosine-1-phosphate receptor 5
SPNS1 spinster homolog 1 (Drosophila)
SPNS2 spinster homolog 2 (Drosophila)
SPNS3 spinster homolog 3 (Drosophila)