somatic diversification of immune receptors via germline recombination within a single locus Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description The process in which immune receptor genes are diversified through recombination of the germline genetic elements within a single genetic locus. (Gene Ontology, GO_0002562)
External Link http://amigo.geneontology.org/amigo/term/GO:0002562
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Genes

35 genes participating in the somatic diversification of immune receptors via germline recombination within a single locus biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
AICDA activation-induced cytidine deaminase
ATM ATM serine/threonine kinase
BATF basic leucine zipper transcription factor, ATF-like
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
CD40LG CD40 ligand
DCLRE1C DNA cross-link repair 1C
ERCC1 excision repair cross-complementation group 1
EXO1 exonuclease 1
EXOSC3 exosome component 3
EXOSC6 exosome component 6
HMGB1 high mobility group box 1
HMGB2 high mobility group box 2
HSPD1 heat shock 60kDa protein 1 (chaperonin)
LEF1 lymphoid enhancer-binding factor 1
LIG1 ligase I, DNA, ATP-dependent
LIG3 ligase III, DNA, ATP-dependent
LIG4 ligase IV, DNA, ATP-dependent
MLH1 mutL homolog 1
MSH2 mutS homolog 2
MSH3 mutS homolog 3
MSH6 mutS homolog 6
NBN nibrin
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
PRKDC protein kinase, DNA-activated, catalytic polypeptide
RAG1 recombination activating gene 1
RAG2 recombination activating gene 2
RNF168 ring finger protein 168, E3 ubiquitin protein ligase
RNF8 ring finger protein 8, E3 ubiquitin protein ligase
SWAP70 SWAP switching B-cell complex 70kDa subunit
TCF3 transcription factor 3
TCF7 transcription factor 7 (T-cell specific, HMG-box)
UNG uracil-DNA glycosylase
VPRBP Vpr (HIV-1) binding protein
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6