smoking Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

385 genes co-occuring with the biological term smoking in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ACAN aggrecan
ACE angiotensin I converting enzyme
ACP1 acid phosphatase 1, soluble
ADAM17 ADAM metallopeptidase domain 17
ADAM33 ADAM metallopeptidase domain 33
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADIPOQ adiponectin, C1Q and collagen domain containing
ADIPOR1 adiponectin receptor 1
ADM adrenomedullin
ADRA2A adrenoceptor alpha 2A
ADRB2 adrenoceptor beta 2, surface
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AHR aryl hydrocarbon receptor
AHRR aryl-hydrocarbon receptor repressor
AK1 adenylate kinase 1
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALK anaplastic lymphoma receptor tyrosine kinase
ALOX5AP arachidonate 5-lipoxygenase-activating protein
AMH anti-Mullerian hormone
ANGPT2 angiopoietin 2
ANKK1 ankyrin repeat and kinase domain containing 1
ANXA6 annexin A6
APC adenomatous polyposis coli
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APOA1 apolipoprotein A-I
APOC1 apolipoprotein C-I
APOC3 apolipoprotein C-III
APOE apolipoprotein E
AR androgen receptor
ARMS2 age-related maculopathy susceptibility 2
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
ATM ATM serine/threonine kinase
AVP arginine vasopressin
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BDNF brain-derived neurotrophic factor
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BST1 bone marrow stromal cell antigen 1
C3 complement component 3
C4B complement component 4B (Chido blood group)
C5 complement component 5
CALY calcyon neuron-specific vesicular protein
CAT catalase
CCDC38 coiled-coil domain containing 38
CCK cholecystokinin
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCL2 chemokine (C-C motif) ligand 2
CCND1 cyclin D1
CCR1 chemokine (C-C motif) receptor 1
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD14 CD14 molecule
CDC6 cell division cycle 6
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH13 cadherin 13
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CFH complement factor H
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CGB chorionic gonadotropin, beta polypeptide
CHAT choline O-acetyltransferase
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
CHN2 chimerin 2
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal)
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal)
CLU clusterin
CNR1 cannabinoid receptor 1 (brain)
COL2A1 collagen, type II, alpha 1
COMT catechol-O-methyltransferase
CRP C-reactive protein, pentraxin-related
CRYGD crystallin, gamma D
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen)
CSMD1 CUB and Sushi multiple domains 1
CST3 cystatin C
CSTA cystatin A (stefin A)
CTNNA2 catenin (cadherin-associated protein), alpha 2
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR2 chemokine (C-X-C motif) receptor 2
CYBA cytochrome b-245, alpha polypeptide
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP2A13 cytochrome P450, family 2, subfamily A, polypeptide 13
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
CYR61 cysteine-rich, angiogenic inducer, 61
DAPK1 death-associated protein kinase 1
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DRD4 dopamine receptor D4
DUOX1 dual oxidase 1
DUOX2 dual oxidase 2
EGFR epidermal growth factor receptor
EGLN2 egl-9 family hypoxia-inducible factor 2
EGR1 early growth response 1
ELANE elastase, neutrophil expressed
ELAVL2 ELAV like neuron-specific RNA binding protein 2
EPB41 erythrocyte membrane protein band 4.1
EPHA2 EPH receptor A2
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
EPHX2 epoxide hydrolase 2, cytoplasmic
EPO erythropoietin
ERBB2 erb-b2 receptor tyrosine kinase 2
ERCC1 excision repair cross-complementation group 1
ERCC2 excision repair cross-complementation group 2
ERCC4 excision repair cross-complementation group 4
ERCC5 excision repair cross-complementation group 5
ERCC6 excision repair cross-complementation group 6
ESR1 estrogen receptor 1
EXO1 exonuclease 1
F2RL3 coagulation factor II (thrombin) receptor-like 3
F5 coagulation factor V (proaccelerin, labile factor)
FAS Fas cell surface death receptor
FBXO32 F-box protein 32
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FGF23 fibroblast growth factor 23
FGFR1 fibroblast growth factor receptor 1
FGFR3 fibroblast growth factor receptor 3
FGG fibrinogen gamma chain
FHIT fragile histidine triad
FLG filaggrin
FLT1 fms-related tyrosine kinase 1
FMO3 flavin containing monooxygenase 3
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXJ1 forkhead box J1
FOXO3 forkhead box O3
FPR1 formyl peptide receptor 1
FTO fat mass and obesity associated
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GCG glucagon
GCKR glucokinase (hexokinase 4) regulator
GCLC glutamate-cysteine ligase, catalytic subunit
GGT1 gamma-glutamyltransferase 1
GHR growth hormone receptor
GHSR growth hormone secretagogue receptor
GNAS GNAS complex locus
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GOT1 glutamic-oxaloacetic transaminase 1, soluble
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GPX1 glutathione peroxidase 1
GRID2 glutamate receptor, ionotropic, delta 2
GRM5 glutamate receptor, metabotropic 5
GRM7 glutamate receptor, metabotropic 7
GRPR gastrin-releasing peptide receptor
GSK3B glycogen synthase kinase 3 beta
GSTA1 glutathione S-transferase alpha 1
GSTK1 glutathione S-transferase kappa 1
GSTM1 glutathione S-transferase mu 1
GSTM3 glutathione S-transferase mu 3 (brain)
GSTM4 glutathione S-transferase mu 4
GSTO1 glutathione S-transferase omega 1
GSTO2 glutathione S-transferase omega 2
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HCRT hypocretin (orexin) neuropeptide precursor
HDAC2 histone deacetylase 2
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HEXB hexosaminidase B (beta polypeptide)
HFE hemochromatosis
HHIP hedgehog interacting protein
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HINT1 histidine triad nucleotide binding protein 1
HLA-A major histocompatibility complex, class I, A
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMOX1 heme oxygenase 1
HNF1A HNF1 homeobox A
HP haptoglobin
HPRT1 hypoxanthine phosphoribosyltransferase 1
HRAS Harvey rat sarcoma viral oncogene homolog
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA1A heat shock 70kDa protein 1A
HSPA4 heat shock 70kDa protein 4
HSPB1 heat shock 27kDa protein 1
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
HTRA1 HtrA serine peptidase 1
HYKK hydroxylysine kinase
ICAM1 intercellular adhesion molecule 1
ICOSLG inducible T-cell co-stimulator ligand
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2 insulin-like growth factor 2
IL10 interleukin 10
IL13 interleukin 13
IL15 interleukin 15
IL17A interleukin 17A
IL17F interleukin 17F
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL4R interleukin 4 receptor
IL5 interleukin 5
IL6 interleukin 6
ING4 inhibitor of growth family, member 4
INS insulin
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITLN1 intelectin 1 (galactofuranose binding)
JUN jun proto-oncogene
KCTD8 potassium channel tetramerization domain containing 8
KDM4C lysine (K)-specific demethylase 4C
KMT2A lysine (K)-specific methyltransferase 2A
KRAS Kirsten rat sarcoma viral oncogene homolog
L1RE1 LINE1 retrotransposable element 1
LCT lactase
LEP leptin
LPL lipoprotein lipase
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LRRK2 leucine-rich repeat kinase 2
LTA lymphotoxin alpha
LYZ lysozyme
MAOA monoamine oxidase A
MAOB monoamine oxidase B
MAPT microtubule-associated protein tau
MBL2 mannose-binding lectin (protein C) 2, soluble
MGMT O-6-methylguanine-DNA methyltransferase
MIR101-1 microRNA 101-1
MIR106B microRNA 106b
MIR124-2 microRNA 124-2
MIR124-3 microRNA 124-3
MIR140 microRNA 140
MIR144 microRNA 144
MIR146A microRNA 146a
MIR499A microRNA 499a
MIR9-3 microRNA 9-3
MKI67 marker of proliferation Ki-67
MLH1 mutL homolog 1
MMP1 matrix metallopeptidase 1
MMP12 matrix metallopeptidase 12
MMP2 matrix metallopeptidase 2
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MSH2 mutS homolog 2
MSTN myostatin
MSX1 msh homeobox 1
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
MUC4 mucin 4, cell surface associated
MUTYH mutY homolog
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NBN nibrin
NCOA3 nuclear receptor coactivator 3
NFE2L2 nuclear factor, erythroid 2-like 2
NOD2 nucleotide-binding oligomerization domain containing 2
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NQO1 NAD(P)H dehydrogenase, quinone 1
NR1I3 nuclear receptor subfamily 1, group I, member 3
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR3C2 nuclear receptor subfamily 3, group C, member 2
NRXN1 neurexin 1
NRXN3 neurexin 3
OGG1 8-oxoguanine DNA glycosylase
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OPRM1 opioid receptor, mu 1
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PADI4 peptidyl arginine deiminase, type IV
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PARK2 parkin RBR E3 ubiquitin protein ligase
PARP1 poly (ADP-ribose) polymerase 1
PENK proenkephalin
PGF placental growth factor
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
PON1 paraoxonase 1
POR P450 (cytochrome) oxidoreductase
PPARG peroxisome proliferator-activated receptor gamma
PROKR1 prokineticin receptor 1
PTEN phosphatase and tensin homolog
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGES prostaglandin E synthase
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RAD23B RAD23 homolog B (S. cerevisiae)
RARB retinoic acid receptor, beta
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBP4 retinol binding protein 4, plasma
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
RECK reversion-inducing-cysteine-rich protein with kazal motifs
RETNLB resistin like beta
RGS17 regulator of G-protein signaling 17
RHD Rh blood group, D antigen
RHOA ras homolog family member A
RNASE3 ribonuclease, RNase A family, 3
RPA1 replication protein A1, 70kDa
RUNX3 runt-related transcription factor 3
RXRG retinoid X receptor, gamma
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFTPA1 surfactant protein A1
SFTPB surfactant protein B
SFTPD surfactant protein D
SIRT1 sirtuin 1
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SNAI2 snail family zinc finger 2
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOD2 superoxide dismutase 2, mitochondrial
SPP1 secreted phosphoprotein 1
SREBF2 sterol regulatory element binding transcription factor 2
SSBP2 single-stranded DNA binding protein 2
SSTR3 somatostatin receptor 3
STAT4 signal transducer and activator of transcription 4
STK11 serine/threonine kinase 11
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
TCF3 transcription factor 3
TCF4 transcription factor 4
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TF transferrin
TFRC transferrin receptor
TG thyroglobulin
TGFB1 transforming growth factor, beta 1
THBD thrombomodulin
TIMP1 TIMP metallopeptidase inhibitor 1
TLR2 toll-like receptor 2
TNF tumor necrosis factor
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNIP1 TNFAIP3 interacting protein 1
TP53 tumor protein p53
TP63 tumor protein p63
TPH1 tryptophan hydroxylase 1
TPH2 tryptophan hydroxylase 2
TRIB1 tribbles pseudokinase 1
TRIB3 tribbles pseudokinase 3
TSLP thymic stromal lymphopoietin
TTC12 tetratricopeptide repeat domain 12
TTF1 transcription termination factor, RNA polymerase I
TYMS thymidylate synthetase
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7
UGT2B10 UDP glucuronosyltransferase 2 family, polypeptide B10
VASP vasodilator-stimulated phosphoprotein
VCAM1 vascular cell adhesion molecule 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VEGFC vascular endothelial growth factor C
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VKORC1 vitamin K epoxide reductase complex, subunit 1
VWF von Willebrand factor
WFDC2 WAP four-disulfide core domain 2
WWC1 WW and C2 domain containing 1
XPC xeroderma pigmentosum, complementation group C
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
ZMYND10 zinc finger, MYND-type containing 10