smoking Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description disease cluster belonging to disease group cancer (Genetic Association Database)
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Genes

87 genes associated with the disease smoking in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ACTN1 actinin, alpha 1
ADRA2A adrenoceptor alpha 2A
APOE apolipoprotein E
BBX bobby sox homolog (Drosophila)
BDNF brain-derived neurotrophic factor
CABLES1 Cdk5 and Abl enzyme substrate 1
CAMKK1 calcium/calmodulin-dependent protein kinase kinase 1, alpha
CDH23 cadherin-related 23
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal)
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal)
COL1A1 collagen, type I, alpha 1
COMT catechol-O-methyltransferase
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DRD2 dopamine receptor D2
EGLN2 egl-9 family hypoxia-inducible factor 2
ERCC1 excision repair cross-complementation group 1
ERCC2 excision repair cross-complementation group 2
ESR1 estrogen receptor 1
EXO1 exonuclease 1
FGB fibrinogen beta chain
FGFR3 fibroblast growth factor receptor 3
FHIT fragile histidine triad
FUT2 fucosyltransferase 2 (secretor status included)
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
GPX1 glutathione peroxidase 1
GRB14 growth factor receptor-bound protein 14
GRIK2 glutamate receptor, ionotropic, kainate 2
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRM8 glutamate receptor, metabotropic 8
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
IL15 interleukin 15
IL1A interleukin 1, alpha
IL6 interleukin 6
KRAS Kirsten rat sarcoma viral oncogene homolog
LPL lipoprotein lipase
LRP5 low density lipoprotein receptor-related protein 5
MAOA monoamine oxidase A
MBL2 mannose-binding lectin (protein C) 2, soluble
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NOS3 nitric oxide synthase 3 (endothelial cell)
NQO1 NAD(P)H dehydrogenase, quinone 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRXN1 neurexin 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OGG1 8-oxoguanine DNA glycosylase
OPRM1 opioid receptor, mu 1
PADI4 peptidyl arginine deiminase, type IV
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC9A9 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
TGFB1 transforming growth factor, beta 1
THBD thrombomodulin
TP53 tumor protein p53
TPH1 tryptophan hydroxylase 1
TRPC5 transient receptor potential cation channel, subfamily C, member 5
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
XPA xeroderma pigmentosum, complementation group A
XPC xeroderma pigmentosum, complementation group C
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZNF138 zinc finger protein 138
ZNF92 zinc finger protein 92
ZNF93 zinc finger protein 93