smoking cessation Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Discontinuation of the habit of smoking, the inhaling and exhaling of tobacco smoke. (Experimental Factor Ontology, EFO_0004319)
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Genes

171 genes associated with the disease smoking cessation in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ACOT11 acyl-CoA thioesterase 11
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5
AKAP13 A kinase (PRKA) anchor protein 13
ALS2 amyotrophic lateral sclerosis 2 (juvenile)
ANXA13 annexin A13
ARMC3 armadillo repeat containing 3
ASB17 ankyrin repeat and SOCS box containing 17
ATMIN ATM interactor
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
BANF2 barrier to autointegration factor 2
BFSP1 beaded filament structural protein 1, filensin
C14ORF37 chromosome 14 open reading frame 37
C16ORF46 chromosome 16 open reading frame 46
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CASP7 caspase 7, apoptosis-related cysteine peptidase
CAT catalase
CCDC25 coiled-coil domain containing 25
CCIN calicin
CDCA7L cell division cycle associated 7-like
CDH13 cadherin 13
CDH19 cadherin 19, type 2
CENPN centromere protein N
CERKL ceramide kinase-like
CES1P1 carboxylesterase 1 pseudogene 1
CLIC5 chloride intracellular channel 5
CLSTN2 calsyntenin 2
CLTA clathrin, light chain A
CMC2 C-x(9)-C motif containing 2
COMT catechol-O-methyltransferase
CPNE4 copine IV
CRYGA crystallin, gamma A
CRYGB crystallin, gamma B
CRYGC crystallin, gamma C
CRYGD crystallin, gamma D
CRYGEP crystallin, gamma E, pseudogene
CSMD1 CUB and Sushi multiple domains 1
CTNNA2 catenin (cadherin-associated protein), alpha 2
CTNNA3 catenin (cadherin-associated protein), alpha 3
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila)
DAPK1 death-associated protein kinase 1
DNAH11 dynein, axonemal, heavy chain 11
EDDM3A epididymal protein 3A
EDDM3B epididymal protein 3B
ELMO1 engulfment and cell motility 1
EQTN equatorin, sperm acrosome associated
F2RL2 coagulation factor II (thrombin) receptor-like 2
FDX1 ferredoxin 1
FLJ45825
FOXF1 forkhead box F1
GCSH glycine cleavage system protein H (aminomethyl carrier)
GFOD1 glucose-fructose oxidoreductase domain containing 1
GLIPR2 GLI pathogenesis-related 2
GLIS3 GLIS family zinc finger 3
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRM5 glutamate receptor, metabotropic 5
GRM7 glutamate receptor, metabotropic 7
GRP gastrin-releasing peptide
GTSF1L gametocyte specific factor 1-like
HABP2 hyaluronan binding protein 2
HSBP1 heat shock factor binding protein 1
IFNG interferon, gamma
IL22 interleukin 22
IL26 interleukin 26
IQGAP2 IQ motif containing GTPase activating protein 2
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNK18 potassium channel, two pore domain subfamily K, member 18
KCNK2 potassium channel, two pore domain subfamily K, member 2
KL klotho
KLHL38 kelch-like family member 38
LAMA1 laminin, alpha 1
LGTN ligatin
LMCD1 LIM and cysteine-rich domains 1
LPP LIM domain containing preferred translocation partner in lipoma
LRRTM3 leucine rich repeat transmembrane neuronal 3
MAML2 mastermind-like 2 (Drosophila)
MAN2A1 mannosidase, alpha, class 2A, member 1
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MCPH1 microcephalin 1
MDM1 Mdm1 nuclear protein homolog (mouse)
MPP4 membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
MROH7 maestro heat-like repeat family member 7
MRPS18CP2 mitochondrial ribosomal protein S18C pseudogene 2
MRPS7P1 mitochondrial ribosomal protein S7 pseudogene 1
MSR1 macrophage scavenger receptor 1
MTHFSD methenyltetrahydrofolate synthetase domain containing
MYO18B myosin XVIIIB
MYPN myopalladin
NRAP nebulin-related anchoring protein
OR10A2 olfactory receptor, family 10, subfamily A, member 2
OR10A5 olfactory receptor, family 10, subfamily A, member 5
OR5AQ1P olfactory receptor, family 5, subfamily AQ, member 1 pseudogene
OR5AS1 olfactory receptor, family 5, subfamily AS, member 1
OR5BE1P olfactory receptor, family 5, subfamily BE, member 1 pseudogene
OR5BN1P olfactory receptor, family 5, subfamily BN, member 1 pseudogene
OR5BN2P olfactory receptor, family 5, subfamily BN, member 2 pseudogene
OR5J1P olfactory receptor, family 5, subfamily J, member 1 pseudogene
OR8H2 olfactory receptor, family 8, subfamily H, member 2
OR8H3 olfactory receptor, family 8, subfamily H, member 3
OR8I2 olfactory receptor, family 8, subfamily I, member 2
OR8I4P olfactory receptor, family 8, subfamily I, member 4 pseudogene
OR8J3 olfactory receptor, family 8, subfamily J, member 3
OVGP1 oviductal glycoprotein 1, 120kDa
P3H2 prolyl 3-hydroxylase 2
PAMR1 peptidase domain containing associated with muscle regeneration 1
PCDH15 protocadherin-related 15
PCNX pecanex homolog (Drosophila)
PCSK2 proprotein convertase subtilisin/kexin type 2
PELI2 pellino E3 ubiquitin protein ligase family member 2
PHACTR1 phosphatase and actin regulator 1
PIFO primary cilia formation
PKD1L2 polycystic kidney disease 1-like 2 (gene/pseudogene)
PKP1 plakophilin 1
PLEKHS1 pleckstrin homology domain containing, family S member 1
PPAPDC1A phosphatidic acid phosphatase type 2 domain containing 1A
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PRDM11 PR domain containing 11
PRND prion protein 2 (dublet)
PRNT prion protein (testis specific)
PTPRD protein tyrosine phosphatase, receptor type, D
PTPRT protein tyrosine phosphatase, receptor type, T
QSOX1 quiescin Q6 sulfhydryl oxidase 1
RAD18 RAD18 E3 ubiquitin protein ligase
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RASSF5 Ras association (RalGDS/AF-6) domain family member 5
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RBMS3 RNA binding motif, single stranded interacting protein 3
RELN reelin
RGS6 regulator of G-protein signaling 6
RIMS2 regulating synaptic membrane exocytosis 2
RIN3 Ras and Rab interactor 3
RNASE6 ribonuclease, RNase A family, k6
RNF144A ring finger protein 144A
ROR1 receptor tyrosine kinase-like orphan receptor 1
RORA RAR-related orphan receptor A
RPS27AP2 ribosomal protein S27a pseudogene 2
RYR3 ryanodine receptor 3
SALL4 spalt-like transcription factor 4
SEC11C SEC11 homolog C (S. cerevisiae)
SEPT11 septin 11
SERPINA11 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11
SERPINA9 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9
SGCZ sarcoglycan, zeta
SH3GL2 SH3-domain GRB2-like 2
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SNAP25 synaptosomal-associated protein, 25kDa
SNCAIP synuclein, alpha interacting protein
SORCS1 sortilin-related VPS10 domain containing receptor 1
SPATA6L spermatogenesis associated 6-like
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
STARD13 StAR-related lipid transfer (START) domain containing 13
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
SYT13 synaptotagmin XIII
TBC1D7 TBC1 domain family, member 7
TEK TEK tyrosine kinase, endothelial
TGFBI transforming growth factor, beta-induced, 68kDa
THSD4 thrombospondin, type I, domain containing 4
UNC5D unc-5 homolog D (C. elegans)
USH2A Usher syndrome 2A (autosomal recessive, mild)
WDFY4 WDFY family member 4
WDR77 WD repeat domain 77
WWOX WW domain containing oxidoreductase
ZNF299P zinc finger protein 299, pseudogene
ZNF365 zinc finger protein 365