skimmianine-6242 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the skimmianine-6242 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALS2CL ALS2 C-terminal like
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ASPH aspartate beta-hydroxylase
ASTN2 astrotactin 2
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BMP4 bone morphogenetic protein 4
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C9ORF9 chromosome 9 open reading frame 9
CAPN9 calpain 9
CCL23 chemokine (C-C motif) ligand 23
CDK9 cyclin-dependent kinase 9
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CHKB choline kinase beta
COL14A1 collagen, type XIV, alpha 1
COL6A1 collagen, type VI, alpha 1
CRABP1 cellular retinoic acid binding protein 1
CUL4B cullin 4B
DAGLA diacylglycerol lipase, alpha
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
ELOVL5 ELOVL fatty acid elongase 5
EMP1 epithelial membrane protein 1
EXTL3 exostosin-like glycosyltransferase 3
FAM204A family with sequence similarity 204, member A
FOSL2 FOS-like antigen 2
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GAS7 growth arrest-specific 7
GJA4 gap junction protein, alpha 4, 37kDa
GOSR2 golgi SNAP receptor complex member 2
HLA-B major histocompatibility complex, class I, B
HSF1 heat shock transcription factor 1
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFITM1 interferon induced transmembrane protein 1
IFNA14 interferon, alpha 14
IFT140 intraflagellar transport 140
IL2RG interleukin 2 receptor, gamma
INCENP inner centromere protein antigens 135/155kDa
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
IRF4 interferon regulatory factor 4
IRF9 interferon regulatory factor 9
IRS2 insulin receptor substrate 2
ISG15 ISG15 ubiquitin-like modifier
ITGB4 integrin, beta 4
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KIAA0040 KIAA0040
KIAA0485 uncharacterized LOC57235
KIF13B kinesin family member 13B
KLF11 Kruppel-like factor 11
LPCAT3 lysophosphatidylcholine acyltransferase 3
MAN1A1 mannosidase, alpha, class 1A, member 1
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MARK4 MAP/microtubule affinity-regulating kinase 4
MASP2 mannan-binding lectin serine peptidase 2
MBD3 methyl-CpG binding domain protein 3
MTCP1 mature T-cell proliferation 1
NADK NAD kinase
NAGLU N-acetylglucosaminidase, alpha
NF2 neurofibromin 2 (merlin)
NPFFR1 neuropeptide FF receptor 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OASL 2'-5'-oligoadenylate synthetase-like
PCDHA5 protocadherin alpha 5
PDE4DIP phosphodiesterase 4D interacting protein
PHOX2B paired-like homeobox 2b
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PPT2 palmitoyl-protein thioesterase 2
PRDM2 PR domain containing 2, with ZNF domain
PRKCA protein kinase C, alpha
PROL1 proline rich, lacrimal 1
QKI QKI, KH domain containing, RNA binding
RAB6B RAB6B, member RAS oncogene family
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RBP4 retinol binding protein 4, plasma
RCE1 Ras converting CAAX endopeptidase 1
RNF122 ring finger protein 122
RUFY3 RUN and FYVE domain containing 3
S100A2 S100 calcium binding protein A2
SCAMP1 secretory carrier membrane protein 1
SETD8 SET domain containing (lysine methyltransferase) 8
SIRPA signal-regulatory protein alpha
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
SP1 Sp1 transcription factor
SP110 SP110 nuclear body protein
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STRN striatin, calmodulin binding protein
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
UBOX5 U-box domain containing 5
WDR1 WD repeat domain 1
WIPF1 WAS/WASL interacting protein family, member 1
ZBTB48 zinc finger and BTB domain containing 48
ZMYND8 zinc finger, MYND-type containing 8

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABHD14A abhydrolase domain containing 14A
AEN apoptosis enhancing nuclease
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATAD5 ATPase family, AAA domain containing 5
AXIN1 axin 1
BAX BCL2-associated X protein
C11ORF80 chromosome 11 open reading frame 80
C1D C1D nuclear receptor corepressor
C1ORF56 chromosome 1 open reading frame 56
C6ORF47 chromosome 6 open reading frame 47
CCDC25 coiled-coil domain containing 25
CENPJ centromere protein J
CERK ceramide kinase
CFD complement factor D (adipsin)
CLCN5 chloride channel, voltage-sensitive 5
CLDN15 claudin 15
CROT carnitine O-octanoyltransferase
CRY1 cryptochrome circadian clock 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DHDDS dehydrodolichyl diphosphate synthase
DSE dermatan sulfate epimerase
E2F8 E2F transcription factor 8
EFHD2 EF-hand domain family, member D2
F3 coagulation factor III (thromboplastin, tissue factor)
FBXL15 F-box and leucine-rich repeat protein 15
FBXO5 F-box protein 5
GLB1L2 galactosidase, beta 1-like 2
GLI3 GLI family zinc finger 3
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
HIRA histone cell cycle regulator
HIST1H2BC histone cluster 1, H2bc
HPSE heparanase
INO80D INO80 complex subunit D
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
KCNK15 potassium channel, two pore domain subfamily K, member 15
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KIF23 kinesin family member 23
LAMA3 laminin, alpha 3
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LOC642236 FSHD region gene 1 pseudogene
LRRC20 leucine rich repeat containing 20
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
MEIS1 Meis homeobox 1
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NEK11 NIMA-related kinase 11
NES nestin
NPIPB15 nuclear pore complex interacting protein family, member B15
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PCOLCE2 procollagen C-endopeptidase enhancer 2
PDZRN3 PDZ domain containing ring finger 3
PFAS phosphoribosylformylglycinamidine synthase
PLA2G10 phospholipase A2, group X
PMM1 phosphomannomutase 1
PPAP2C phosphatidic acid phosphatase type 2C
PYCRL pyrroline-5-carboxylate reductase-like
RBL1 retinoblastoma-like 1
RINT1 RAD50 interactor 1
RPAP2 RNA polymerase II associated protein 2
RPL13P5 ribosomal protein L13 pseudogene 5
RPL23AP7 ribosomal protein L23a pseudogene 7
SH2D4A SH2 domain containing 4A
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC46A3 solute carrier family 46, member 3
SMAD7 SMAD family member 7
SNHG20 small nucleolar RNA host gene 20
SNX16 sorting nexin 16
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
SYNGR3 synaptogyrin 3
TCTA T-cell leukemia translocation altered
THOP1 thimet oligopeptidase 1
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM165 transmembrane protein 165
TMEM51 transmembrane protein 51
TMEM57 transmembrane protein 57
TPST1 tyrosylprotein sulfotransferase 1
TSPO translocator protein (18kDa)
UBQLN4 ubiquilin 4
URGCP upregulator of cell proliferation
VEGFC vascular endothelial growth factor C
WDR18 WD repeat domain 18
ZBTB3 zinc finger and BTB domain containing 3
ZNF219 zinc finger protein 219
ZNF23 zinc finger protein 23
ZNF273 zinc finger protein 273
ZNF408 zinc finger protein 408
ZNF7 zinc finger protein 7
ZNF816 zinc finger protein 816
ZNHIT2 zinc finger, HIT-type containing 2
ZXDC ZXD family zinc finger C