sin3-type complex Gene Set

Dataset GO Cellular Component Annotations
Category structural or functional annotations
Type cellular component
Description Any of a number of evolutionarily conserved histone deacetylase complexes (HDACs) containing a core consisting of a paired amphipathic helix motif protein (e.g. Sin3p in S. cerevisiae, Pst1 in S. pombe or Sin3A in mammals) at least one class I histone deacetylase (e.g. Rpd3p in S. cerevisiae, Clr6 in S. pombe, or HDAC1 and HDAC2 in mammals), and at least one WD40 repeat protein (e.g. Ume1p in S. cerevisiae, Prw1 in S. pombe, or RbAp46 and RbAp48 in mammals). These complexes also contain a variable number of other proteins that direct histone binding, DNA binding, or add other functionality to the complex. (Gene Ontology, GO_0070822)
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15 proteins localized to the sin3-type complex cellular component from the curated GO Cellular Component Annotations dataset.

Symbol Name
BRMS1 breast cancer metastasis suppressor 1
BRMS1L breast cancer metastasis-suppressor 1-like
CSNK2A1 casein kinase 2, alpha 1 polypeptide
FAM60A family with sequence similarity 60, member A
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
ING2 inhibitor of growth family, member 2
MORF4L1 mortality factor 4 like 1
NCOR1 nuclear receptor corepressor 1
PHF12 PHD finger protein 12
RBBP4 retinoblastoma binding protein 4
SIN3A SIN3 transcription regulator family member A
SIN3B SIN3 transcription regulator family member B
SUDS3 suppressor of defective silencing 3 homolog (S. cerevisiae)