serotonin-5633 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the serotonin-5633 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACRV1 acrosomal vesicle protein 1
APAF1 apoptotic peptidase activating factor 1
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
C4BPA complement component 4 binding protein, alpha
CALCA calcitonin-related polypeptide alpha
CCDC57 coiled-coil domain containing 57
CCDC64 coiled-coil domain containing 64
CCKBR cholecystokinin B receptor
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD1A CD1a molecule
CD58 CD58 molecule
CD80 CD80 molecule
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CNN1 calponin 1, basic, smooth muscle
CRYM crystallin, mu
DCTN1 dynactin 1
DIAPH2-AS1 DIAPH2 antisense RNA 1
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
EDA ectodysplasin A
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
EPHB2 EPH receptor B2
FBXO24 F-box protein 24
FBXO41 F-box protein 41
FN1 fibronectin 1
FPR1 formyl peptide receptor 1
G0S2 G0/G1 switch 2
GABRQ gamma-aminobutyric acid (GABA) A receptor, theta
GLT8D2 glycosyltransferase 8 domain containing 2
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GPM6B glycoprotein M6B
GPR153 G protein-coupled receptor 153
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HDC histidine decarboxylase
HFE hemochromatosis
HIST1H3A histone cluster 1, H3a
HIST1H3I histone cluster 1, H3i
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IHH indian hedgehog
IL2RG interleukin 2 receptor, gamma
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JAK3 Janus kinase 3
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNK2 potassium channel, two pore domain subfamily K, member 2
KLHL18 kelch-like family member 18
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
LAMB4 laminin, beta 4
LAMP1 lysosomal-associated membrane protein 1
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
MAPK8 mitogen-activated protein kinase 8
MED25 mediator complex subunit 25
MMP11 matrix metallopeptidase 11
MPZ myelin protein zero
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
MYOZ3 myozenin 3
NCOR2 nuclear receptor corepressor 2
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NOTCH4 notch 4
NOVA2 neuro-oncological ventral antigen 2
OMD osteomodulin
OR12D3 olfactory receptor, family 12, subfamily D, member 3
PLAU plasminogen activator, urokinase
PLD1 phospholipase D1, phosphatidylcholine-specific
PLXNB3 plexin B3
PTGDS prostaglandin D2 synthase 21kDa (brain)
RAB3B RAB3B, member RAS oncogene family
RANBP3 RAN binding protein 3
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RPGRIP1L RPGRIP1-like
RUNX1 runt-related transcription factor 1
SFRP4 secreted frizzled-related protein 4
SIRPA signal-regulatory protein alpha
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SPINK5 serine peptidase inhibitor, Kazal type 5
SPON2 spondin 2, extracellular matrix protein
SSX1 synovial sarcoma, X breakpoint 1
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
TAPBP TAP binding protein (tapasin)
TMPRSS4 transmembrane protease, serine 4
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
UBE3A ubiquitin protein ligase E3A
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
VAV2 vav 2 guanine nucleotide exchange factor
WDR55 WD repeat domain 55
ZNF639 zinc finger protein 639
ZNF710 zinc finger protein 710
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
AFAP1 actin filament associated protein 1
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ARMC7 armadillo repeat containing 7
BTF3P11 basic transcription factor 3 pseudogene 11
C11ORF80 chromosome 11 open reading frame 80
C17ORF80 chromosome 17 open reading frame 80
C19ORF73 chromosome 19 open reading frame 73
CCDC71 coiled-coil domain containing 71
CCDC85C coiled-coil domain containing 85C
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLCN6 chloride channel, voltage-sensitive 6
CLGN calmegin
CXADR coxsackie virus and adenovirus receptor
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DENND5B DENN/MADD domain containing 5B
DOK5 docking protein 5
DRD1 dopamine receptor D1
DUSP13 dual specificity phosphatase 13
EFNA3 ephrin-A3
EPN1 epsin 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM155A family with sequence similarity 155, member A
FGF6 fibroblast growth factor 6
FKBP1B FK506 binding protein 1B, 12.6 kDa
FRMD1 FERM domain containing 1
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GFI1 growth factor independent 1 transcription repressor
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GRAMD1C GRAM domain containing 1C
GRPR gastrin-releasing peptide receptor
GSTT1 glutathione S-transferase theta 1
HOXB2 homeobox B2
IFT140 intraflagellar transport 140
IL4R interleukin 4 receptor
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KIAA0754 KIAA0754
LIN7A lin-7 homolog A (C. elegans)
LINC00597 long intergenic non-protein coding RNA 597
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LRP5L low density lipoprotein receptor-related protein 5-like
LRRC37A3 leucine rich repeat containing 37, member A3
MANBA mannosidase, beta A, lysosomal
MAPKBP1 mitogen-activated protein kinase binding protein 1
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
NOL12 nucleolar protein 12
OXCT2 3-oxoacid CoA transferase 2
PARP16 poly (ADP-ribose) polymerase family, member 16
PCDHGB5 protocadherin gamma subfamily B, 5
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PPL periplakin
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PRSS16 protease, serine, 16 (thymus)
RAB3D RAB3D, member RAS oncogene family
RANGRF RAN guanine nucleotide release factor
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RFXAP regulatory factor X-associated protein
RHBDD3 rhomboid domain containing 3
RIN1 Ras and Rab interactor 1
RIN2 Ras and Rab interactor 2
RPL10L ribosomal protein L10-like
RPL23AP32 ribosomal protein L23a pseudogene 32
RWDD2A RWD domain containing 2A
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC12A8 solute carrier family 12, member 8
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SNX15 sorting nexin 15
SOWAHC sosondowah ankyrin repeat domain family member C
STRA6 stimulated by retinoic acid 6
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SYT17 synaptotagmin XVII
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TM6SF1 transmembrane 6 superfamily member 1
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNS2 tensin 2
TTBK2 tau tubulin kinase 2
UBXN6 UBX domain protein 6
USP27X ubiquitin specific peptidase 27, X-linked
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
ZDHHC14 zinc finger, DHHC-type containing 14
ZFP37 ZFP37 zinc finger protein
ZNF10 zinc finger protein 10
ZNF446 zinc finger protein 446
ZNF711 zinc finger protein 711
ZNF750 zinc finger protein 750
ZNF787 zinc finger protein 787
ZNF862 zinc finger protein 862