semilunar valve regurgitation Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description the backward reflux of blood through the semilunar valve(s), due to insufficiency caused by disease, aging or congenital malformation (Mammalian Phenotype Ontology, MP_0006049)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0006049
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Genes

9 gene mutations causing the semilunar valve regurgitation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
EGFR epidermal growth factor receptor
GJA1 gap junction protein, alpha 1, 43kDa
IDUA iduronidase, alpha-L-
KLF3 Kruppel-like factor 3 (basic)
LOX lysyl oxidase
MUS81 MUS81 structure-specific endonuclease subunit
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
PLCE1 phospholipase C, epsilon 1
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C