selegiline-2826 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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190 genes differentially expressed following the selegiline-2826 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ADD3 adducin 3 (gamma)
AGO4 argonaute RISC catalytic component 4
AMN amnion associated transmembrane protein
ARHGAP33 Rho GTPase activating protein 33
ARTN artemin
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BHLHE40 basic helix-loop-helix family, member e40
C10ORF95 chromosome 10 open reading frame 95
C9ORF9 chromosome 9 open reading frame 9
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC132 coiled-coil domain containing 132
CCDC85C coiled-coil domain containing 85C
COPZ2 coatomer protein complex, subunit zeta 2
CRISP1 cysteine-rich secretory protein 1
CTNND2 catenin (cadherin-associated protein), delta 2
DGCR9 DiGeorge syndrome critical region gene 9 (non-protein coding)
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DRD2 dopamine receptor D2
DUSP9 dual specificity phosphatase 9
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
EMID1 EMI domain containing 1
ERN1 endoplasmic reticulum to nucleus signaling 1
EXOG endo/exonuclease (5'-3'), endonuclease G-like
FGD1 FYVE, RhoGEF and PH domain containing 1
FOXN3 forkhead box N3
FRMD4A FERM domain containing 4A
GADD45G growth arrest and DNA-damage-inducible, gamma
GLRA1 glycine receptor, alpha 1
GMPR guanosine monophosphate reductase
GRIP2 glutamate receptor interacting protein 2
GRK5 G protein-coupled receptor kinase 5
HOXC4 homeobox C4
HPS1 Hermansky-Pudlak syndrome 1
IFT27 intraflagellar transport 27
IPO5 importin 5
ITGA10 integrin, alpha 10
KDM8 lysine (K)-specific demethylase 8
KLHL25 kelch-like family member 25
LAMC2 laminin, gamma 2
LINC01587 long intergenic non-protein coding RNA 1587
LMOD1 leiomodin 1 (smooth muscle)
LRRC8B leucine rich repeat containing 8 family, member B
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LYST lysosomal trafficking regulator
MAOB monoamine oxidase B
MAP1S microtubule-associated protein 1S
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MMP24 matrix metallopeptidase 24 (membrane-inserted)
MMP25 matrix metallopeptidase 25
MTCP1 mature T-cell proliferation 1
MTERF4 mitochondrial transcription termination factor 4
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NCALD neurocalcin delta
NDRG2 NDRG family member 2
NEU3 sialidase 3 (membrane sialidase)
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
OPLAH 5-oxoprolinase (ATP-hydrolysing)
PICK1 protein interacting with PRKCA 1
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLXNC1 plexin C1
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1)
PRB1 proline-rich protein BstNI subfamily 1
PSG11 pregnancy specific beta-1-glycoprotein 11
PSG6 pregnancy specific beta-1-glycoprotein 6
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PVR poliovirus receptor
QPCTL glutaminyl-peptide cyclotransferase-like
RASA3 RAS p21 protein activator 3
RHBDD3 rhomboid domain containing 3
RPS3A ribosomal protein S3A
SCARA3 scavenger receptor class A, member 3
SFTPB surfactant protein B
SH3BP2 SH3-domain binding protein 2
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SORBS1 sorbin and SH3 domain containing 1
SPON1 spondin 1, extracellular matrix protein
STRA6 stimulated by retinoic acid 6
SYNDIG1 synapse differentiation inducing 1
TAGLN3 transgelin 3
TAOK2 TAO kinase 2
TAT tyrosine aminotransferase
TBX2 T-box 2
TCP10 t-complex 10
TMEM53 transmembrane protein 53
TNC tenascin C
TRD T cell receptor delta locus
TRIM21 tripartite motif containing 21
YPEL1 yippee-like 1 (Drosophila)
ZBTB7A zinc finger and BTB domain containing 7A
ZFP64 ZFP64 zinc finger protein

decreased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ATAD3A ATPase family, AAA domain containing 3A
BCORL1 BCL6 corepressor-like 1
BPGM 2,3-bisphosphoglycerate mutase
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
CALCOCO1 calcium binding and coiled-coil domain 1
CAPN15 calpain 15
CBX4 chromobox homolog 4
CHML choroideremia-like (Rab escort protein 2)
CORT cortistatin
CTC1 CTS telomere maintenance complex component 1
CTNNBIP1 catenin, beta interacting protein 1
DARS2 aspartyl-tRNA synthetase 2, mitochondrial
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DGAT1 diacylglycerol O-acyltransferase 1
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
EGLN1 egl-9 family hypoxia-inducible factor 1
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EPHA2 EPH receptor A2
ERCC4 excision repair cross-complementation group 4
FAM179B family with sequence similarity 179, member B
FAM198B family with sequence similarity 198, member B
FCF1 FCF1 rRNA-processing protein
FKBP14 FK506 binding protein 14, 22 kDa
FRS2 fibroblast growth factor receptor substrate 2
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
GAREM GRB2 associated, regulator of MAPK1
GCHFR GTP cyclohydrolase I feedback regulator
GDAP1 ganglioside induced differentiation associated protein 1
GLS2 glutaminase 2 (liver, mitochondrial)
HIRA histone cell cycle regulator
ISOC1 isochorismatase domain containing 1
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LEMD3 LEM domain containing 3
LIG4 ligase IV, DNA, ATP-dependent
LINC00115 long intergenic non-protein coding RNA 115
LINS lines homolog (Drosophila)
LRP5 low density lipoprotein receptor-related protein 5
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAGEF1 melanoma antigen family F1
MATK megakaryocyte-associated tyrosine kinase
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MTMR6 myotubularin related protein 6
NABP2 nucleic acid binding protein 2
NCS1 neuronal calcium sensor 1
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NEK11 NIMA-related kinase 11
NRBF2 nuclear receptor binding factor 2
NRGN neurogranin (protein kinase C substrate, RC3)
ORAI3 ORAI calcium release-activated calcium modulator 3
OXR1 oxidation resistance 1
PGPEP1 pyroglutamyl-peptidase I
PHC1 polyhomeotic homolog 1 (Drosophila)
PHEX phosphate regulating endopeptidase homolog, X-linked
PILRB paired immunoglobin-like type 2 receptor beta
PLEKHA5 pleckstrin homology domain containing, family A member 5
PODXL2 podocalyxin-like 2
POLH polymerase (DNA directed), eta
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRPH peripherin
PTK6 protein tyrosine kinase 6
PTPRE protein tyrosine phosphatase, receptor type, E
PYCRL pyrroline-5-carboxylate reductase-like
R3HCC1L R3H domain and coiled-coil containing 1-like
RLN2 relaxin 2
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPGR retinitis pigmentosa GTPase regulator
RSF1 remodeling and spacing factor 1
SETD6 SET domain containing 6
SLC12A8 solute carrier family 12, member 8
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SP1 Sp1 transcription factor
TAGLN transgelin
TARP TCR gamma alternate reading frame protein
TBX19 T-box 19
TCEAL1 transcription elongation factor A (SII)-like 1
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM104 transmembrane protein 104
TMEM132A transmembrane protein 132A
TPST2 tyrosylprotein sulfotransferase 2
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TSPYL2 TSPY-like 2
TTC33 tetratricopeptide repeat domain 33
TUBG2 tubulin, gamma 2
UEVLD UEV and lactate/malate dehyrogenase domains
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
WWC2 WW and C2 domain containing 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZBTB48 zinc finger and BTB domain containing 48
ZNF280D zinc finger protein 280D
ZNF573 zinc finger protein 573