selective immunoglobulin deficiency disease Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:6025
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Genes

179 genes associated with the disease selective immunoglobulin deficiency disease in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 1.63263
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 1.46571
IL13 interleukin 13 1.16893
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 0.668836
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 0.64645
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 0.593633
IFIH1 interferon induced with helicase C domain 1 0.50329
RAD50 RAD50 homolog (S. cerevisiae) 0.468362
IL4R interleukin 4 receptor 0.461977
CLEC16A C-type lectin domain family 16, member A 0.456271
LINC00299 long intergenic non-protein coding RNA 299 0.456271
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13 0.452375
HLA-A major histocompatibility complex, class I, A 0.444357
LRP1 low density lipoprotein receptor-related protein 1 0.443613
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 0.44241
ZBTB39 zinc finger and BTB domain containing 39 0.440739
WWP2 WW domain containing E3 ubiquitin protein ligase 2 0.438494
LPP LIM domain containing preferred translocation partner in lipoma 0.430311
DGKZ diacylglycerol kinase, zeta 0.430311
UBE2R2 ubiquitin-conjugating enzyme E2R 2 0.429912
COL26A1 collagen, type XXVI, alpha 1 0.427411
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 0.419335
C5ORF56 chromosome 5 open reading frame 56 0.417177
FAS Fas cell surface death receptor 0.417062
SIK2 salt-inducible kinase 2 0.413315
UBAP2 ubiquitin associated protein 2 0.411496
HLA-H major histocompatibility complex, class I, H (pseudogene) 0.411023
ZNRD1-AS1 ZNRD1 antisense RNA 1 0.410937
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 0.408213
C2ORF83 chromosome 2 open reading frame 83 0.408097
HLA-J major histocompatibility complex, class I, J (pseudogene) 0.407856
HDAC4 histone deacetylase 4 0.406468
CASR calcium-sensing receptor 0.405994
NRCAM neuronal cell adhesion molecule 0.405309
HSF2BP heat shock transcription factor 2 binding protein 0.403326
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 0.403229
MSI2 musashi RNA-binding protein 2 0.402941
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 0.402565
FOXP1 forkhead box P1 0.402198
DOT1L DOT1-like histone H3K79 methyltransferase 0.401319
MICA MHC class I polypeptide-related sequence A 0.401319
TBC1D31 TBC1 domain family, member 31 0.400898
PCDH15 protocadherin-related 15 0.400248
CD86 CD86 molecule 0.398956
CARD14 caspase recruitment domain family, member 14 0.396467
MAK male germ cell-associated kinase 0.396323
TRIM26 tripartite motif containing 26 0.395481
C17ORF99 chromosome 17 open reading frame 99 0.395481
LRP1B low density lipoprotein receptor-related protein 1B 0.395142
LAMC3 laminin, gamma 3 0.393727
NRP1 neuropilin 1 0.393542
PPP2R2B protein phosphatase 2, regulatory subunit B, beta 0.39242
PPP2R1B protein phosphatase 2, regulatory subunit A, beta 0.392192
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.392136
FMN2 formin 2 0.392024
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2 0.391968
CSTA cystatin A (stefin A) 0.391913
RFC3 replication factor C (activator 1) 3, 38kDa 0.391259
LOC440600 uncharacterized LOC440600 0.389248
MTCL1 microtubule crosslinking factor 1 0.389248
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.38878
SHROOM3 shroom family member 3 0.388461
CNTN4 contactin 4 0.387536
MYH13 myosin, heavy chain 13, skeletal muscle 0.387408
MAP2 microtubule-associated protein 2 0.386299
EDAR ectodysplasin A receptor 0.386101
FAM162A family with sequence similarity 162, member A 0.385597
FAXC failed axon connections homolog (Drosophila) 0.385521
ECT2L epithelial cell transforming 2 like 0.385446
IRF8 interferon regulatory factor 8 0.385072
HCG9 HLA complex group 9 (non-protein coding) 0.384851
TMPRSS7 transmembrane protease, serine 7 0.384598
DRD2 dopamine receptor D2 0.383941
CDK6 cyclin-dependent kinase 6 0.383903
TIMMDC1 translocase of inner mitochondrial membrane domain containing 1 0.383522
CNTNAP2 contactin associated protein-like 2 0.383446
CD80 CD80 molecule 0.383409
C15ORF40 chromosome 15 open reading frame 40 0.382602
GSK3B glycogen synthase kinase 3 beta 0.382246
LVRN laeverin 0.382141
KCNIP1 Kv channel interacting protein 1 0.382001
OR10J1 olfactory receptor, family 10, subfamily J, member 1 0.381623
RELN reelin 0.381386
ASTL astacin-like metallo-endopeptidase (M12 family) 0.381252
AAA1 aortic aneurysm, familial abdominal 1 0.380856
ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 0.380436
GDE1 glycerophosphodiester phosphodiesterase 1 0.379809
RORA RAR-related orphan receptor A 0.379748
ETV5 ets variant 5 0.379054
PARP9 poly (ADP-ribose) polymerase family, member 9 0.378995
PTPDC1 protein tyrosine phosphatase domain containing 1 0.378615
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.378272
KIF26B kinesin family member 26B 0.378103
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.377769
ADGRB1 adhesion G protein-coupled receptor B1 0.377522
PTPRG protein tyrosine phosphatase, receptor type, G 0.377414
AHI1 Abelson helper integration site 1 0.377225
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 0.377012
ARHGAP31 Rho GTPase activating protein 31 0.375564
TRIM31 tripartite motif containing 31 0.375225
SRL sarcalumenin 0.375081
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.374963
SETBP1 SET binding protein 1 0.374381
CADM3 cell adhesion molecule 3 0.373952
CELF1 CUGBP, Elav-like family member 1 0.373818
DOCK2 dedicator of cytokinesis 2 0.37373
FGGY FGGY carbohydrate kinase domain containing 0.37373
GRM5 glutamate receptor, metabotropic 5 0.373554
SORCS2 sortilin-related VPS10 domain containing receptor 2 0.373272
MAP6D1 MAP6 domain containing 1 0.372952
OSBPL10 oxysterol binding protein-like 10 0.372889
ZNF622 zinc finger protein 622 0.37241
KPNA1 karyopherin alpha 1 (importin alpha 5) 0.372004
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1 0.371706
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 0.370911
MARC1 mitochondrial amidoxime reducing component 1 0.37017
TK1 thymidine kinase 1, soluble 0.369791
RYR3 ryanodine receptor 3 0.369056
PDE4D phosphodiesterase 4D, cAMP-specific 0.367835
LRP6 low density lipoprotein receptor-related protein 6 0.367835
MYO18B myosin XVIIIB 0.367667
FOXN3 forkhead box N3 0.3675
CSMD1 CUB and Sushi multiple domains 1 0.366848
DACH2 dachshund family transcription factor 2 0.366689
RAB11FIP4 RAB11 family interacting protein 4 (class II) 0.366531
ZNF185 zinc finger protein 185 (LIM domain) 0.365911
PHACTR2 phosphatase and actin regulator 2 0.365459
CAMKMT calmodulin-lysine N-methyltransferase 0.365164
DNMBP dynamin binding protein 0.364028
ARHGAP30 Rho GTPase activating protein 30 0.363486
GLIS3 GLIS family zinc finger 3 0.3627
RHBG Rh family, B glycoprotein (gene/pseudogene) 0.36146
CD46 CD46 molecule, complement regulatory protein 0.361341
FAM167A family with sequence similarity 167, member A 0.360525
CCDC50 coiled-coil domain containing 50 0.359964
MYEOV2 myeloma overexpressed 2 0.359744
GUCD1 guanylyl cyclase domain containing 1 0.359419
C1ORF87 chromosome 1 open reading frame 87 0.35858
CNTN6 contactin 6 0.35858
RELL1 RELT-like 1 0.358174
NCAM1 neural cell adhesion molecule 1 0.358074
ARHGAP21 Rho GTPase activating protein 21 0.357777
DCUN1D1 DCN1, defective in cullin neddylation 1, domain containing 1 0.357679
PDE1A phosphodiesterase 1A, calmodulin-dependent 0.357679
TMEM30C transmembrane protein 30C 0.357582
GREM2 gremlin 2, DAN family BMP antagonist 0.357389
CHD6 chromodomain helicase DNA binding protein 6 0.35657
LOC646736 uncharacterized LOC646736 0.354606
GXYLT1 glucoside xylosyltransferase 1 0.353513
ELL elongation factor RNA polymerase II 0.353162
NUB1 negative regulator of ubiquitin-like proteins 1 0.352988
TACR1 tachykinin receptor 1 0.352731
RSU1 Ras suppressor protein 1 0.352477
SULF2 sulfatase 2 0.352309
TPRG1 tumor protein p63 regulated 1 0.352225
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.352142
TECR trans-2,3-enoyl-CoA reductase 0.351733
DYSF dysferlin 0.351571
SORBS2 sorbin and SH3 domain containing 2 0.35149
NKAIN2 Na+/K+ transporting ATPase interacting 2 0.350859
APCDD1L adenomatosis polyposis coli down-regulated 1-like 0.349005
FBLN1 fibulin 1 0.348934
CHODL chondrolectin 0.348104
TULP4 tubby like protein 4 0.346921
MRPL53 mitochondrial ribosomal protein L53 0.345804
CLHC1 clathrin heavy chain linker domain containing 1 0.345684
MOGS mannosyl-oligosaccharide glucosidase 0.345093
B3GALTL beta 1,3-galactosyltransferase-like 0.344977
PCLO piccolo presynaptic cytomatrix protein 0.344294
RRP1B ribosomal RNA processing 1B 0.344183
NALCN sodium leak channel, non selective 0.343962
MYO5C myosin VC 0.343419
KCTD14 potassium channel tetramerization domain containing 14 0.342276
LPCAT1 lysophosphatidylcholine acyltransferase 1 0.341343
CDH23 cadherin-related 23 0.34089
RAD51B RAD51 paralog B 0.340336
IYD iodotyrosine deiodinase 0.338246
MUC22 mucin 22 0.332927
KIAA1107 KIAA1107 0.329558