secretory granule Gene Set

Dataset LOCATE Curated Protein Localization Annotations
Category proteomics
Type cellular component
Description A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules. (Gene Ontology, GO_0030141)
External Link http://locate.imb.uq.edu.au/searchpages/HumanGO:0030141.shtml
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Genes

55 proteins localized to the secretory granule cellular component in low- or high-throughput protein localization assays from the LOCATE Curated Protein Localization Annotations dataset.

Symbol Name
ARSB arylsulfatase B
BDNF brain-derived neurotrophic factor
CAMP cathelicidin antimicrobial peptide
CCR3 chemokine (C-C motif) receptor 3
CD207 CD207 molecule, langerin
CGB chorionic gonadotropin, beta polypeptide
CLC Charcot-Leyden crystal galectin
CMA1 chymase 1, mast cell
CNTN1 contactin 1
CPA3 carboxypeptidase A3 (mast cell)
CPE carboxypeptidase E
DEFA4 defensin, alpha 4, corticostatin
DEFA5 defensin, alpha 5, Paneth cell-specific
DEFA6 defensin, alpha 6, Paneth cell-specific
ELANE elastase, neutrophil expressed
GAL galanin/GMAP prepropeptide
GCK glucokinase (hexokinase 4)
GHRL ghrelin/obestatin prepropeptide
GKN1 gastrokine 1
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
GNLY granulysin
GP2 glycoprotein 2 (zymogen granule membrane)
GZMK granzyme K (granzyme 3; tryptase II)
GZMM granzyme M (lymphocyte met-ase 1)
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IAPP islet amyloid polypeptide
ICA1 islet cell autoantigen 1, 69kDa
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
LCN2 lipocalin 2
NTF3 neurotrophin 3
PAM peptidylglycine alpha-amidating monooxygenase
PCSK5 proprotein convertase subtilisin/kexin type 5
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PRTN3 proteinase 3
PTPRN protein tyrosine phosphatase, receptor type, N
RAB26 RAB26, member RAS oncogene family
RAB37 RAB37, member RAS oncogene family
RAB3D RAB3D, member RAS oncogene family
RNASE4 ribonuclease, RNase A family, 4
RPH3AL rabphilin 3A-like (without C2 domains)
SCAMP1 secretory carrier membrane protein 1
SCAMP2 secretory carrier membrane protein 2
SCG3 secretogranin III
SCG5 secretogranin V
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SCRG1 stimulator of chondrogenesis 1
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SNAP23 synaptosomal-associated protein, 23kDa
STXBP2 syntaxin binding protein 2
SYT2 synaptotagmin II
TPSB2 tryptase beta 2 (gene/pseudogene)
TPSD1 tryptase delta 1
TPSG1 tryptase gamma 1
TRAF7 TNF receptor-associated factor 7, E3 ubiquitin protein ligase
VWF von Willebrand factor