secretory granule Gene Set

Dataset GO Cellular Component Annotations
Category structural or functional annotations
Type cellular component
Description A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules. (Gene Ontology, GO_0030141)
External Link http://amigo.geneontology.org/amigo/term/GO:0030141
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Genes

197 proteins localized to the secretory granule cellular component from the curated GO Cellular Component Annotations dataset.

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ACPP acid phosphatase, prostate
ACRBP acrosin binding protein
ACRV1 acrosomal vesicle protein 1
ADAM15 ADAM metallopeptidase domain 15
ADAM8 ADAM metallopeptidase domain 8
AKAP3 A kinase (PRKA) anchor protein 3
ANGPTL6 angiopoietin-like 6
ANXA11 annexin A11
ANXA3 annexin A3
ARC activity-regulated cytoskeleton-associated protein
ARSA arylsulfatase A
ASTL astacin-like metallo-endopeptidase (M12 family)
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
ATP6V1E2 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2
ATP7A ATPase, Cu++ transporting, alpha polypeptide
AVP arginine vasopressin
AZU1 azurocidin 1
BMF Bcl2 modifying factor
BRCA2 breast cancer 2, early onset
C9ORF9 chromosome 9 open reading frame 9
CALR calreticulin
CAMP cathelicidin antimicrobial peptide
CAPN11 calpain 11
CAPZA3 capping protein (actin filament) muscle Z-line, alpha 3
CARTPT CART prepropeptide
CASC5 cancer susceptibility candidate 5
CATSPER3 cation channel, sperm associated 3
CATSPER4 cation channel, sperm associated 4
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1)
CDC42 cell division cycle 42
CEP131 centrosomal protein 131kDa
CHGA chromogranin A
CHGB chromogranin B
CLCN3 chloride channel, voltage-sensitive 3
CLK3 CDC-like kinase 3
CLU clusterin
COL1A1 collagen, type I, alpha 1
CPA3 carboxypeptidase A3 (mast cell)
CRCP CGRP receptor component
CRHBP corticotropin releasing hormone binding protein
CRISP3 cysteine-rich secretory protein 3
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTSG cathepsin G
CTSH cathepsin H
CTSV cathepsin V
CXADR coxsackie virus and adenovirus receptor
CYBA cytochrome b-245, alpha polypeptide
DENND4C DENN/MADD domain containing 4C
DRD2 dopamine receptor D2
EBAG9 estrogen receptor binding site associated, antigen, 9
ECE1 endothelin converting enzyme 1
EDN1 endothelin 1
ELANE elastase, neutrophil expressed
EXOC3L1 exocyst complex component 3-like 1
FABP9 fatty acid binding protein 9, testis
FGA fibrinogen alpha chain
FGB fibrinogen beta chain
FGG fibrinogen gamma chain
FNDC3A fibronectin type III domain containing 3A
FSTL3 follistatin-like 3 (secreted glycoprotein)
GAL galanin/GMAP prepropeptide
GARS glycyl-tRNA synthetase
GCK glucokinase (hexokinase 4)
GHRHR growth hormone releasing hormone receptor
GKN1 gastrokine 1
GLIPR1L1 GLI pathogenesis-related 1 like 1
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
GNAT3 guanine nucleotide binding protein, alpha transducing 3
HCRT hypocretin (orexin) neuropeptide precursor
HEXB hexosaminidase B (beta polypeptide)
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HILPDA hypoxia inducible lipid droplet-associated
HPS4 Hermansky-Pudlak syndrome 4
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IL1B interleukin 1, beta
IQUB IQ motif and ubiquitin domain containing
ITGA1 integrin, alpha 1
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLK13 kallikrein-related peptidase 13
KLK5 kallikrein-related peptidase 5
KLK7 kallikrein-related peptidase 7
LACRT lacritin
LAMP1 lysosomal-associated membrane protein 1
LOXL1 lysyl oxidase-like 1
LTF lactotransferrin
MPO myeloperoxidase
MYO5A myosin VA (heavy chain 12, myoxin)
MYRIP myosin VIIA and Rab interacting protein
NAPSA napsin A aspartic peptidase
NCF2 neutrophil cytosolic factor 2
NCS1 neuronal calcium sensor 1
NOTCH1 notch 1
NPPC natriuretic peptide C
OLFM4 olfactomedin 4
OXT oxytocin/neurophysin I prepropeptide
PATE4 prostate and testis expressed 4
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor
PCSK5 proprotein convertase subtilisin/kexin type 5
PLA2G1B phospholipase A2, group IB (pancreas)
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLAT plasminogen activator, tissue
POMC proopiomelanocortin
POMT1 protein-O-mannosyltransferase 1
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RAB10 RAB10, member RAS oncogene family
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAB12 RAB12, member RAS oncogene family
RAB13 RAB13, member RAS oncogene family
RAB27A RAB27A, member RAS oncogene family
RAB27B RAB27B, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
RAB3D RAB3D, member RAS oncogene family
RAB4A RAB4A, member RAS oncogene family
RAB4B RAB4B, member RAS oncogene family
RAB7A RAB7A, member RAS oncogene family
RACGAP1 Rac GTPase activating protein 1
RESP18 regulated endocrine-specific protein 18
RPH3A rabphilin 3A
SCG2 secretogranin II
SCG5 secretogranin V
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SEMG1 semenogelin I
SEMG2 semenogelin II
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFTPC surfactant protein C
SKIL SKI-like proto-oncogene
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SLC30A8 solute carrier family 30 (zinc transporter), member 8
SLIRP SRA stem-loop interacting RNA binding protein
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SNAP23 synaptosomal-associated protein, 23kDa
SNAPIN SNAP-associated protein
SOD1 superoxide dismutase 1, soluble
SPACA3 sperm acrosome associated 3
SPACA4 sperm acrosome associated 4
SPACA7 sperm acrosome associated 7
SPAG8 sperm associated antigen 8
SPAG9 sperm associated antigen 9
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPESP1 sperm equatorial segment protein 1
SPINK5 serine peptidase inhibitor, Kazal type 5
SRGN serglycin
STK31 serine/threonine kinase 31
STX1A syntaxin 1A (brain)
STX3 syntaxin 3
STX4 syntaxin 4
STX7 syntaxin 7
STXBP1 syntaxin binding protein 1
STXBP2 syntaxin binding protein 2
STXBP3 syntaxin binding protein 3
SV2B synaptic vesicle glycoprotein 2B
SYPL1 synaptophysin-like 1
SYT1 synaptotagmin I
SYT4 synaptotagmin IV
SYT5 synaptotagmin V
SYT7 synaptotagmin VII
SYT8 synaptotagmin VIII
SYT9 synaptotagmin IX
SYTL4 synaptotagmin-like 4
TBC1D21 TBC1 domain family, member 21
TBXA2R thromboxane A2 receptor
TCP1 t-complex 1
TCTEX1D4 Tctex1 domain containing 4
TEX22 testis expressed 22
TFF3 trefoil factor 3 (intestinal)
THBS1 thrombospondin 1
THBS2 thrombospondin 2
TOR1A torsin family 1, member A (torsin A)
TREML1 triggering receptor expressed on myeloid cells-like 1
TRH thyrotropin-releasing hormone
TRIM36 tripartite motif containing 36
TSKS testis-specific serine kinase substrate
TSSK1B testis-specific serine kinase 1B
TSSK2 testis-specific serine kinase 2
TXNDC8 thioredoxin domain containing 8 (spermatozoa)
UNC13D unc-13 homolog D (C. elegans)
USP8 ubiquitin specific peptidase 8
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VAMP3 vesicle-associated membrane protein 3
VAMP7 vesicle-associated membrane protein 7
VAMP8 vesicle-associated membrane protein 8
VEGFA vascular endothelial growth factor A
VEZT vezatin, adherens junctions transmembrane protein
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)
VPS33B vacuolar protein sorting 33 homolog B (yeast)
VWF von Willebrand factor
ZP1 zona pellucida glycoprotein 1 (sperm receptor)
ZP2 zona pellucida glycoprotein 2 (sperm receptor)
ZP3 zona pellucida glycoprotein 3 (sperm receptor)
ZPBP zona pellucida binding protein
ZPBP2 zona pellucida binding protein 2