secretory diarrhea Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description Secretory diarrhea is a diarrhea where there is an increase in the active secretion, or there is an inhibition of absorption causing little to no structural damage. The most common cause of this type of diarrhea is a cholera toxin that stimulates the secretion of anions, especially chloride ions. (Human Disease Ontology, DOID_0050129)
Similar Terms
Downloads & Tools

Genes

85 genes co-occuring with the disease secretory diarrhea in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
SNX18 sorting nexin 18 1.64038
PDZD3 PDZ domain containing 3 1.63859
SST somatostatin 1.58983
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 1.58046
SHANK2 SH3 and multiple ankyrin repeat domains 2 1.50447
MYO5B myosin VB 1.48428
GUCY2C guanylate cyclase 2C 1.43157
VIP vasoactive intestinal peptide 1.36814
GCC2 GRIP and coiled-coil domain containing 2 1.36727
NPR1 natriuretic peptide receptor 1 1.28479
PRKG2 protein kinase, cGMP-dependent, type II 1.27781
PDZK1 PDZ domain containing 1 1.22909
GCC1 GRIP and coiled-coil domain containing 1 1.18755
SLC26A3 solute carrier family 26 (anion exchanger), member 3 1.15666
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 1.12108
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 1.05429
DERL1 derlin 1 1.00625
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 0.990222
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 0.984321
SORBS2 sorbin and SH3 domain containing 2 0.97212
PPY pancreatic polypeptide 0.962053
PRKG1 protein kinase, cGMP-dependent, type I 0.937459
CALCOCO2 calcium binding and coiled-coil domain 2 0.889258
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 0.873281
GAST gastrin 0.828229
TRIM44 tripartite motif containing 44 0.789262
GOPC golgi-associated PDZ and coiled-coil motif containing 0.785574
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 0.753713
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.732596
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.732191
SUB1 SUB1 homolog (S. cerevisiae) 0.727333
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.725716
RAB11A RAB11A, member RAS oncogene family 0.71078
GRASP GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein 0.675112
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 0.67113
GPR135 G protein-coupled receptor 135 0.6608
SYVN1 synovial apoptosis inhibitor 1, synoviolin 0.592895
MYO6 myosin VI 0.585887
ALYREF Aly/REF export factor 0.573828
BEST1 bestrophin 1 0.56722
SLC26A6 solute carrier family 26 (anion exchanger), member 6 0.560616
TJP1 tight junction protein 1 0.559062
ADORA2B adenosine A2b receptor 0.554791
LPAR2 lysophosphatidic acid receptor 2 0.549747
CHGA chromogranin A 0.504207
FLOT1 flotillin 1 0.484364
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3 0.481325
CALCA calcitonin-related polypeptide alpha 0.476772
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 0.466928
FABP2 fatty acid binding protein 2, intestinal 0.449571
DNAH8 dynein, axonemal, heavy chain 8 0.427765
RAB8A RAB8A, member RAS oncogene family 0.419517
CALB1 calbindin 1, 28kDa 0.410161
TAC1 tachykinin, precursor 1 0.406798
CHEK1 checkpoint kinase 1 0.402318
NPY neuropeptide Y 0.401199
MRPL49 mitochondrial ribosomal protein L49 0.400453
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 0.391513
ALPI alkaline phosphatase, intestinal 0.387423
NT5E 5'-nucleotidase, ecto (CD73) 0.347879
SSTR1 somatostatin receptor 1 0.331025
NTS neurotensin 0.312464
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.312102
PTAFR platelet-activating factor receptor 0.309566
PDE4D phosphodiesterase 4D, cAMP-specific 0.298371
SSTR5 somatostatin receptor 5 0.296211
P4HB prolyl 4-hydroxylase, beta polypeptide 0.294053
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.286519
ANO1 anoctamin 1, calcium activated chloride channel 0.28616
MME membrane metallo-endopeptidase 0.279724
NPPC natriuretic peptide C 0.274376
CHAT choline O-acetyltransferase 0.260538
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa 0.257005
SGK1 serum/glucocorticoid regulated kinase 1 0.249608
MYO7A myosin VIIA 0.242945
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 0.211934
CCK cholecystokinin 0.203933
NAAA N-acylethanolamine acid amidase 0.20229
LTF lactotransferrin 0.19582
SSTR2 somatostatin receptor 2 0.1936
PYY peptide YY 0.178403
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.174093
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) 0.173832
KLK1 kallikrein 1 0.171286
NOG noggin 0.165001