secretory cell Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description Cell specialised for secretion, usually epithelial. Those that secrete proteins characteristically have well developed rough endoplasmic reticulum, whereas conspicuous smooth endoplasmic reticulum is typical of cells that secrete lipid or lipid derived products (e.g. Steroids). (BRENDA Tissue and Enzyme Source Ontology, BTO_0003659)
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Genes

352 proteins co-occuring with the tissue secretory cell in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
OVGP1 oviductal glycoprotein 1, 120kDa 1.81124
ATOH1 atonal homolog 1 (Drosophila) 1.51095
XBP1 X-box binding protein 1 1.41768
ERN1 endoplasmic reticulum to nucleus signaling 1 1.33093
MUC5B mucin 5B, oligomeric mucus/gel-forming 1.27919
RAB27A RAB27A, member RAS oncogene family 1.26263
RAB3D RAB3D, member RAS oncogene family 1.2461
RAB3A RAB3A, member RAS oncogene family 1.23004
BHLHA15 basic helix-loop-helix family, member a15 1.21935
MUC2 mucin 2, oligomeric mucus/gel-forming 1.21757
ATF6 activating transcription factor 6 1.20734
ELANE elastase, neutrophil expressed 1.18779
CGB7 chorionic gonadotropin, beta polypeptide 7 1.18113
CGB5 chorionic gonadotropin, beta polypeptide 5 1.17713
CGB chorionic gonadotropin, beta polypeptide 1.1585
CGB8 chorionic gonadotropin, beta polypeptide 8 1.15717
LYZ lysozyme 1.15185
SYT2 synaptotagmin II 1.14343
NSF N-ethylmaleimide-sensitive factor 1.12837
INS insulin 1.1142
DNAH8 dynein, axonemal, heavy chain 8 1.10889
CSN1S1 casein alpha s1 1.10579
LACRT lacritin 1.10093
UNC13B unc-13 homolog B (C. elegans) 1.0625
ACPP acid phosphatase, prostate 1.06074
SYTL4 synaptotagmin-like 4 1.05985
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 1.05633
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 1.02951
POMC proopiomelanocortin 1.02425
CHGA chromogranin A 1.01681
SCIN scinderin 0.998908
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.992814
SSTR4 somatostatin receptor 4 0.976315
KRT14 keratin 14, type I 0.973283
STXBP1 syntaxin binding protein 1 0.970686
RAB27B RAB27B, member RAS oncogene family 0.961607
PRL prolactin 0.952978
VIP vasoactive intestinal peptide 0.948239
RAB3B RAB3B, member RAS oncogene family 0.945656
LALBA lactalbumin, alpha- 0.943935
RAB3C RAB3C, member RAS oncogene family 0.941355
SST somatostatin 0.92291
RPH3A rabphilin 3A 0.922055
AQP5 aquaporin 5 0.919916
SSTR3 somatostatin receptor 3 0.919488
DDRGK1 DDRGK domain containing 1 0.919488
NOTCH1 notch 1 0.91308
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.896895
GAST gastrin 0.872327
AR androgen receptor 0.860942
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast) 0.85505
NUCB1 nucleobindin 1 0.854629
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 0.852948
FOXJ1 forkhead box J1 0.851686
EIF2A eukaryotic translation initiation factor 2A, 65kDa 0.850845
SSTR5 somatostatin receptor 5 0.835737
NPS neuropeptide S 0.834061
NGEF neuronal guanine nucleotide exchange factor 0.82736
ALOX15B arachidonate 15-lipoxygenase, type B 0.814397
PI4KB phosphatidylinositol 4-kinase, catalytic, beta 0.811473
SPDEF SAM pointed domain containing ETS transcription factor 0.800208
MARCKS myristoylated alanine-rich protein kinase C substrate 0.794375
SYT8 synaptotagmin VIII 0.788964
SYT1 synaptotagmin I 0.786468
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2 0.780648
SYT7 synaptotagmin VII 0.779401
MUC7 mucin 7, secreted 0.77774
GFI1 growth factor independent 1 transcription repressor 0.775249
SSTR1 somatostatin receptor 1 0.772759
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 0.761984
STX6 syntaxin 6 0.756604
KRT7 keratin 7, type II 0.740503
SCGB3A2 secretoglobin, family 3A, member 2 0.739678
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 0.7335
KLK3 kallikrein-related peptidase 3 0.726918
STX4 syntaxin 4 0.722809
PHF13 PHD finger protein 13 0.722398
NEUROG3 neurogenin 3 0.711319
FUZ fuzzy planar cell polarity protein 0.707221
CALCA calcitonin-related polypeptide alpha 0.702308
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11 0.699444
LTF lactotransferrin 0.694946
REG3G regenerating islet-derived 3 gamma 0.691268
MUC6 mucin 6, oligomeric mucus/gel-forming 0.690042
POFUT1 protein O-fucosyltransferase 1 0.685959
PSCA prostate stem cell antigen 0.685551
TBC1D10A TBC1 domain family, member 10A 0.678617
MUC4 mucin 4, cell surface associated 0.677803
NPPA natriuretic peptide A 0.663555
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 0.662336
RAB6C RAB6C, member RAS oncogene family 0.662336
CHGB chromogranin B 0.661523
SNAP23 synaptosomal-associated protein, 23kDa 0.658678
CA6 carbonic anhydrase VI 0.655836
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.650966
TFF2 trefoil factor 2 0.650966
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.65056
MUC1 mucin 1, cell surface associated 0.650154
CCK cholecystokinin 0.649344
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.649344
VAMP3 vesicle-associated membrane protein 3 0.630718
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10 0.630314
USO1 USO1 vesicle transport factor 0.628293
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b 0.625465
TSPYL1 TSPY-like 1 0.623043
RAB26 RAB26, member RAS oncogene family 0.622639
SNAPIN SNAP-associated protein 0.622639
AGR2 anterior gradient 2 0.622235
KRT5 keratin 5, type II 0.621831
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 0.611346
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.605709
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits 0.599675
TXN thioredoxin 0.599273
SCG3 secretogranin III 0.59405
BTN1A1 butyrophilin, subfamily 1, member A1 0.59405
TGOLN2 trans-golgi network protein 2 0.588031
GAS8 growth arrest-specific 8 0.584422
ALPPL2 alkaline phosphatase, placental-like 2 0.58242
ALPL alkaline phosphatase, liver/bone/kidney 0.582019
ALPP alkaline phosphatase, placental 0.581218
TFF3 trefoil factor 3 (intestinal) 0.579617
MUC16 mucin 16, cell surface associated 0.578816
GNPTG N-acetylglucosamine-1-phosphate transferase, gamma subunit 0.569222
GCG glucagon 0.567227
P4HB prolyl 4-hydroxylase, beta polypeptide 0.563637
UFM1 ubiquitin-fold modifier 1 0.56284
STXBP3 syntaxin binding protein 3 0.558856
AQP3 aquaporin 3 (Gill blood group) 0.55607
ANXA2 annexin A2 0.55249
SLC9B2 solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2 0.551695
AMACR alpha-methylacyl-CoA racemase 0.551298
PAX2 paired box 2 0.548914
NKX2-8 NK2 homeobox 8 0.547326
KRT8 keratin 8, type II 0.541773
SP140 SP140 nuclear body protein 0.540981
GSN gelsolin 0.539
OTOG otogelin 0.537812
OLFM4 olfactomedin 4 0.533856
CA2 carbonic anhydrase II 0.53346
PTH parathyroid hormone 0.528323
GH1 growth hormone 1 0.525166
SCG2 secretogranin II 0.524771
VAMP8 vesicle-associated membrane protein 8 0.521617
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.512957
PSAP prosaposin 0.510599
TP53 tumor protein p53 0.507457
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1 0.507064
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 0.506279
SAMD4A sterile alpha motif domain containing 4A 0.502357
SELT selenoprotein T 0.498832
LRRC26 leucine rich repeat containing 26 0.495309
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma 0.482817
CREB3 cAMP responsive element binding protein 3 0.482817
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.482428
GPR78 G protein-coupled receptor 78 0.482038
DLL1 delta-like 1 (Drosophila) 0.480091
WRNIP1 Werner helicase interacting protein 1 0.477756
ANXA1 annexin A1 0.475812
ATP11A ATPase, class VI, type 11A 0.471539
CSN2 casein beta 0.466885
SCG5 secretogranin V 0.465335
FOXA2 forkhead box A2 0.464174
PAX8 paired box 8 0.463787
CDH10 cadherin 10, type 2 (T2-cadherin) 0.462239
SYTL2 synaptotagmin-like 2 0.460305
RIMS2 regulating synaptic membrane exocytosis 2 0.457987
RAB22A RAB22A, member RAS oncogene family 0.454126
CHIA chitinase, acidic 0.451813
GPX8 glutathione peroxidase 8 (putative) 0.451042
STX2 syntaxin 2 0.449116
ERP44 endoplasmic reticulum protein 44 0.448731
SCGB1D2 secretoglobin, family 1D, member 2 0.446038
BCHE butyrylcholinesterase 0.444499
ASCL2 achaete-scute family bHLH transcription factor 2 0.442194
ESR1 estrogen receptor 1 0.442194
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 0.43989
FTL ferritin, light polypeptide 0.438356
MYO5A myosin VA (heavy chain 12, myoxin) 0.435672
TAC1 tachykinin, precursor 1 0.433757
ORAI1 ORAI calcium release-activated calcium modulator 1 0.43146
FTH1 ferritin, heavy polypeptide 1 0.431077
CD44 CD44 molecule (Indian blood group) 0.428401
FOXM1 forkhead box M1 0.428018
CDK5RAP3 CDK5 regulatory subunit associated protein 3 0.428018
PDIA2 protein disulfide isomerase family A, member 2 0.425726
RAB28 RAB28, member RAS oncogene family 0.423436
DLL4 delta-like 4 (Drosophila) 0.420004
CD79A CD79a molecule, immunoglobulin-associated alpha 0.420004
VIL1 villin 1 0.416195
AVP arginine vasopressin 0.415434
FOXP4 forkhead box P4 0.411251
EXOSC8 exosome component 8 0.407073
GP2 glycoprotein 2 (zymogen granule membrane) 0.405935
HES5 hes family bHLH transcription factor 5 0.400628
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14 0.399492
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.398735
GUSB glucuronidase, beta 0.396465
ENO2 enolase 2 (gamma, neuronal) 0.396087
AZGP1 alpha-2-glycoprotein 1, zinc-binding 0.394576
PEBP1 phosphatidylethanolamine binding protein 1 0.394197
PCNA proliferating cell nuclear antigen 0.393819
CST2 cystatin SA 0.393819
C11ORF58 chromosome 11 open reading frame 58 0.393064
YAP1 Yes-associated protein 1 0.392309
STX1A syntaxin 1A (brain) 0.390421
CRH corticotropin releasing hormone 0.389666
PMVK phosphomevalonate kinase 0.384013
STX3 syntaxin 3 0.379875
PRSS3 protease, serine, 3 0.377996
STIM1 stromal interaction molecule 1 0.377245
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A 0.375743
RAB38 RAB38, member RAS oncogene family 0.374618
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 0.372369
CREB3L2 cAMP responsive element binding protein 3-like 2 0.371994
GUCY2C guanylate cyclase 2C 0.370121
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 0.370121
UPK3A uroplakin 3A 0.369373
ORAI2 ORAI calcium release-activated calcium modulator 2 0.368624
NPR1 natriuretic peptide receptor 1 0.36825
NPY neuropeptide Y 0.367502
H2AFX H2A histone family, member X 0.366007
SND1 staphylococcal nuclease and tudor domain containing 1 0.364139
ISPD isoprenoid synthase domain containing 0.364139
VAMP4 vesicle-associated membrane protein 4 0.362646
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.360782
TFF1 trefoil factor 1 0.358919
VDAC3 voltage-dependent anion channel 3 0.355942
CIC capicua transcriptional repressor 0.350001
SLPI secretory leukocyte peptidase inhibitor 0.341863
PITPNB phosphatidylinositol transfer protein, beta 0.340757
TF transferrin 0.338914
DNER delta/notch-like EGF repeat containing 0.335968
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 0.331927
MGAM maltase-glucoamylase 0.330094
TSPYL2 TSPY-like 2 0.329361
JAG1 jagged 1 0.328628
REN renin 0.326067
MAL2 mal, T-cell differentiation protein 2 (gene/pseudogene) 0.32497
TERF1 telomeric repeat binding factor (NIMA-interacting) 1 0.321685
SLC26A3 solute carrier family 26 (anion exchanger), member 3 0.31877
CLDN10 claudin 10 0.31877
ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 0.31877
SFTPC surfactant protein C 0.318407
ANGPT4 angiopoietin 4 0.318042
CLEC3B C-type lectin domain family 3, member B 0.316588
ACHE acetylcholinesterase (Yt blood group) 0.314772
KRT4 keratin 4, type II 0.312957
SYT3 synaptotagmin III 0.312232
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.309697
GPX7 glutathione peroxidase 7 0.308974
PTPRR protein tyrosine phosphatase, receptor type, R 0.305722
SYP synaptophysin 0.305361
ADCY2 adenylate cyclase 2 (brain) 0.305001
CREB3L4 cAMP responsive element binding protein 3-like 4 0.301758
FOXP1 forkhead box P1 0.301398
CST1 cystatin SN 0.301039
LAT2 linker for activation of T cells family, member 2 0.300679
ITSN1 intersectin 1 (SH3 domain protein) 0.29996
EGFR epidermal growth factor receptor 0.29996
VWF von Willebrand factor 0.295655
CDX1 caudal type homeobox 1 0.295655
CLCN3 chloride channel, voltage-sensitive 3 0.294939
BRCA1 breast cancer 1, early onset 0.293866
ARF1 ADP-ribosylation factor 1 0.293151
EXOC3 exocyst complex component 3 0.290295
RCN1 reticulocalbin 1, EF-hand calcium binding domain 0.290295
EXOC2 exocyst complex component 2 0.289226
MAPK13 mitogen-activated protein kinase 13 0.289226
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12 0.28887
KRT18 keratin 18, type I 0.288158
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 0.287092
MMRN1 multimerin 1 0.285671
MUC17 mucin 17, cell surface associated 0.284607
SCGB3A1 secretoglobin, family 3A, member 1 0.284253
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.28213
MEP1B meprin A, beta 0.281776
GRP gastrin-releasing peptide 0.279659
MEP1A meprin A, alpha (PABA peptide hydrolase) 0.279307
ATF4 activating transcription factor 4 0.278603
AQP10 aquaporin 10 0.2779
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 0.276846
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 0.276145
AGPS alkylglycerone phosphate synthase 0.275444
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c 0.272649
CSN3 casein kappa 0.270214
RAB40AL RAB40A, member RAS oncogene family-like 0.269867
RACGAP1 Rac GTPase activating protein 1 0.268137
MSMB microseminoprotein, beta- 0.266757
INTU inturned planar cell polarity protein 0.265038
CREB3L1 cAMP responsive element binding protein 3-like 1 0.265038
ALB albumin 0.264696
PER2 period circadian clock 2 0.264353
ESR2 estrogen receptor 2 (ER beta) 0.264353
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 0.262986
AGPAT9 1-acylglycerol-3-phosphate O-acyltransferase 9 0.261284
STXBP2 syntaxin binding protein 2 0.261284
KRT2 keratin 2, type II 0.260945
MMP2 matrix metallopeptidase 2 0.259591
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 0.259254
SUB1 SUB1 homolog (S. cerevisiae) 0.257237
HES7 hes family bHLH transcription factor 7 0.255567
BRCA2 breast cancer 2, early onset 0.253578
CGA glycoprotein hormones, alpha polypeptide 0.253248
CLDN2 claudin 2 0.249006
CDC16 cell division cycle 16 0.24676
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) 0.24676
ANXA7 annexin A7 0.244545
ORAI3 ORAI calcium release-activated calcium modulator 3 0.242672
MAL mal, T-cell differentiation protein 0.241132
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.24052
STK3 serine/threonine kinase 3 0.240216
MMP7 matrix metallopeptidase 7 0.23961
TRIM27 tripartite motif containing 27 0.23961
RAP2B RAP2B, member of RAS oncogene family 0.239307
CDK20 cyclin-dependent kinase 20 0.239307
RAB1B RAB1B, member RAS oncogene family 0.239007
SAR1A secretion associated, Ras related GTPase 1A 0.236627
TBK1 TANK-binding kinase 1 0.236627
PGR progesterone receptor 0.236332
ARF3 ADP-ribosylation factor 3 0.235457
MAP2K6 mitogen-activated protein kinase kinase 6 0.234878
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.23459
NGF nerve growth factor (beta polypeptide) 0.233446
MUC13 mucin 13, cell surface associated 0.233162
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.230931
SWAP70 SWAP switching B-cell complex 70kDa subunit 0.228497
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.228497
P2RY14 purinergic receptor P2Y, G-protein coupled, 14 0.227445
FOXI1 forkhead box I1 0.226926
CDK8 cyclin-dependent kinase 8 0.226926
ATL1 atlastin GTPase 1 0.226926
DLL3 delta-like 3 (Drosophila) 0.2259
ICA1 islet cell autoantigen 1, 69kDa 0.225647
ZBTB33 zinc finger and BTB domain containing 33 0.223906
GDI2 GDP dissociation inhibitor 2 0.223662
FOXA1 forkhead box A1 0.223662
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.222699
RUNX1 runt-related transcription factor 1 0.222224
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) 0.219485
RIMS1 regulating synaptic membrane exocytosis 1 0.219485
AHNAK AHNAK nucleoprotein 0.219047
RAB10 RAB10, member RAS oncogene family 0.217974
BSND barttin CLCNK-type chloride channel accessory beta subunit 0.217554
SDC1 syndecan 1 0.217139
RALB v-ral simian leukemia viral oncogene homolog B 0.215928
BPIFA2 BPI fold containing family A, member 2 0.21573
ERP29 endoplasmic reticulum protein 29 0.214202
FN1 fibronectin 1 0.214017
IGF1 insulin-like growth factor 1 (somatomedin C) 0.214017
CD109 CD109 molecule 0.213833
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 0.212761
CRMP1 collapsin response mediator protein 1 0.212761