scopoletin-3131 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the scopoletin-3131 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4
ADTRP androgen-dependent TFPI-regulating protein
AKAP13 A kinase (PRKA) anchor protein 13
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ANKH ANKH inorganic pyrophosphate transport regulator
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
C8A complement component 8, alpha polypeptide
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CAMKV CaM kinase-like vesicle-associated
CASZ1 castor zinc finger 1
CCDC85B coiled-coil domain containing 85B
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CES3 carboxylesterase 3
CFAP69 cilia and flagella associated protein 69
CIB2 calcium and integrin binding family member 2
CNGB3 cyclic nucleotide gated channel beta 3
CRP C-reactive protein, pentraxin-related
CRTC1 CREB regulated transcription coactivator 1
CST4 cystatin S
DCTN2 dynactin 2 (p50)
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
ECE1 endothelin converting enzyme 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EPHA1 EPH receptor A1
EXPH5 exophilin 5
FLRT2 fibronectin leucine rich transmembrane protein 2
FN1 fibronectin 1
FRS3 fibroblast growth factor receptor substrate 3
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GPR22 G protein-coupled receptor 22
GRIK2 glutamate receptor, ionotropic, kainate 2
GSPT1 G1 to S phase transition 1
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HOXB6 homeobox B6
HPCAL4 hippocalcin like 4
HSPG2 heparan sulfate proteoglycan 2
HYAL1 hyaluronoglucosaminidase 1
IDUA iduronidase, alpha-L-
IL7R interleukin 7 receptor
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
IQCA1 IQ motif containing with AAA domain 1
ITGA6 integrin, alpha 6
KALRN kalirin, RhoGEF kinase
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2
KLF6 Kruppel-like factor 6
LIME1 Lck interacting transmembrane adaptor 1
LOX lysyl oxidase
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
MAGEC2 melanoma antigen family C2
MEG3 maternally expressed 3 (non-protein coding)
MET MET proto-oncogene, receptor tyrosine kinase
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MRPS12 mitochondrial ribosomal protein S12
NEK11 NIMA-related kinase 11
NOTCH4 notch 4
OMG oligodendrocyte myelin glycoprotein
OR10H1 olfactory receptor, family 10, subfamily H, member 1
OXCT2 3-oxoacid CoA transferase 2
PCP4 Purkinje cell protein 4
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PICK1 protein interacting with PRKCA 1
POU2F2 POU class 2 homeobox 2
PPARD peroxisome proliferator-activated receptor delta
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PROZ protein Z, vitamin K-dependent plasma glycoprotein
PRR7 proline rich 7 (synaptic)
PRUNE2 prune homolog 2 (Drosophila)
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RCN3 reticulocalbin 3, EF-hand calcium binding domain
RDH5 retinol dehydrogenase 5 (11-cis/9-cis)
RIBC2 RIB43A domain with coiled-coils 2
RTEL1 regulator of telomere elongation helicase 1
RXRB retinoid X receptor, beta
SIDT2 SID1 transmembrane family, member 2
SIGLEC5 sialic acid binding Ig-like lectin 5
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
SNCG synuclein, gamma (breast cancer-specific protein 1)
SOCS2 suppressor of cytokine signaling 2
SPARCL1 SPARC-like 1 (hevin)
SSH3 slingshot protein phosphatase 3
SULT4A1 sulfotransferase family 4A, member 1
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TFDP3 transcription factor Dp family, member 3
THTPA thiamine triphosphatase
TTLL7 tubulin tyrosine ligase-like family member 7
YLPM1 YLP motif containing 1
ZER1 zyg-11 related, cell cycle regulator
ZIC3 Zic family member 3
ZNF407 zinc finger protein 407
ZNF440 zinc finger protein 440
ZSWIM1 zinc finger, SWIM-type containing 1

decreased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ADAM15 ADAM metallopeptidase domain 15
ARHGAP10 Rho GTPase activating protein 10
ARMC6 armadillo repeat containing 6
BBS10 Bardet-Biedl syndrome 10
BEST1 bestrophin 1
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
C17ORF80 chromosome 17 open reading frame 80
C7ORF43 chromosome 7 open reading frame 43
CAPN1 calpain 1, (mu/I) large subunit
CARF calcium responsive transcription factor
CD3D CD3d molecule, delta (CD3-TCR complex)
CENPB centromere protein B, 80kDa
COPS7B COP9 signalosome subunit 7B
CRIP1 cysteine-rich protein 1 (intestinal)
CROT carnitine O-octanoyltransferase
CUL9 cullin 9
CXCL2 chemokine (C-X-C motif) ligand 2
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DAAM1 dishevelled associated activator of morphogenesis 1
ECM1 extracellular matrix protein 1
EGR3 early growth response 3
ELP6 elongator acetyltransferase complex subunit 6
FCMR Fc fragment of IgM receptor
FGF9 fibroblast growth factor 9
GCH1 GTP cyclohydrolase 1
GEM GTP binding protein overexpressed in skeletal muscle
GLCE glucuronic acid epimerase
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GPATCH2L G patch domain containing 2-like
GPX2 glutathione peroxidase 2
GTPBP6 GTP binding protein 6 (putative)
HAUS6 HAUS augmin-like complex, subunit 6
HIST1H1E histone cluster 1, H1e
HPSE heparanase
HRAS Harvey rat sarcoma viral oncogene homolog
IFT81 intraflagellar transport 81
IQSEC2 IQ motif and Sec7 domain 2
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KCTD15 potassium channel tetramerization domain containing 15
KIAA1107 KIAA1107
LINC00260 long intergenic non-protein coding RNA 260
LPAR6 lysophosphatidic acid receptor 6
MAP3K2 mitogen-activated protein kinase kinase kinase 2
METTL2B methyltransferase like 2B
MKL2 MKL/myocardin-like 2
MTMR12 myotubularin related protein 12
MX1 MX dynamin-like GTPase 1
MX2 MX dynamin-like GTPase 2
NR1D2 nuclear receptor subfamily 1, group D, member 2
NT5M 5',3'-nucleotidase, mitochondrial
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
NXPH4 neurexophilin 4
ORAI3 ORAI calcium release-activated calcium modulator 3
PAQR4 progestin and adipoQ receptor family member IV
PARG poly (ADP-ribose) glycohydrolase
PARP16 poly (ADP-ribose) polymerase family, member 16
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PDZD7 PDZ domain containing 7
PEX26 peroxisomal biogenesis factor 26
PIEZO1 piezo-type mechanosensitive ion channel component 1
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PITX2 paired-like homeodomain 2
PKN1 protein kinase N1
PLCD1 phospholipase C, delta 1
PLEC plectin
POM121L2 POM121 transmembrane nucleoporin-like 2
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RHOH ras homolog family member H
RND1 Rho family GTPase 1
SALL2 spalt-like transcription factor 2
SCN10A sodium channel, voltage gated, type X alpha subunit
SIL1 SIL1 nucleotide exchange factor
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3
SLC22A18 solute carrier family 22, member 18
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
ST7L suppression of tumorigenicity 7 like
STBD1 starch binding domain 1
STEAP3 STEAP family member 3, metalloreductase
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
THBS4 thrombospondin 4
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM110 transmembrane protein 110
TOM1 target of myb1 (chicken)
TRABD TraB domain containing
TRAF1 TNF receptor-associated factor 1
TRAF2 TNF receptor-associated factor 2
ULBP2 UL16 binding protein 2
UNC13B unc-13 homolog B (C. elegans)
USP32 ubiquitin specific peptidase 32
XKR8 XK, Kell blood group complex subunit-related family, member 8
ZHX2 zinc fingers and homeoboxes 2
ZKSCAN8 zinc finger with KRAB and SCAN domains 8
ZNF324 zinc finger protein 324
ZNF692 zinc finger protein 692
ZNF862 zinc finger protein 862