salivary gland adenoid cystic carcinoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A salivary gland carcinoma that is characterized by a distinctive pattern in which abnormal nests or cords of epithelial cells surround and/or infiltrate ducts or glandular structures within the affected organ. These structures are typically filled with a mucous-like material or contain abnormal fibrous membranes. (Human Disease Ontology, DOID_4866)
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Genes

233 genes co-occuring with the disease salivary gland adenoid cystic carcinoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
CYLD cylindromatosis (turban tumor syndrome) 1.90614
NFIB nuclear factor I/B 1.87929
ACCS 1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional) 1.835
MYB v-myb avian myeloblastosis viral oncogene homolog 1.77361
TP53 tumor protein p53 1.26168
TDRD12 tudor domain containing 12 1.2395
KRT14 keratin 14, type I 1.21912
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha 1.19834
MAML2 mastermind-like 2 (Drosophila) 1.17722
ERBB2 erb-b2 receptor tyrosine kinase 2 1.15368
PLAG1 pleiomorphic adenoma gene 1 1.11772
CRTC1 CREB regulated transcription coactivator 1 1.11225
CDH12 cadherin 12, type 2 (N-cadherin 2) 1.08831
KRT7 keratin 7, type II 1.07782
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.07656
KRT5 keratin 5, type II 1.07614
PA2G4 proliferation-associated 2G4, 38kDa 1.06522
NKX2-4 NK2 homeobox 4 1.04041
JTB jumping translocation breakpoint 1.03872
LBX2 ladybird homeobox 2 0.999924
SLIT3 slit homolog 3 (Drosophila) 0.961216
AIG1 androgen-induced 1 0.942858
WIBG within bgcn homolog (Drosophila) 0.922974
PGR progesterone receptor 0.908965
SLC35D3 solute carrier family 35, member D3 0.899924
GLIPR1L1 GLI pathogenesis-related 1 like 1 0.886799
PARVG parvin, gamma 0.874509
MMP9 matrix metallopeptidase 9 0.872462
KRT8 keratin 8, type II 0.870006
PCNA proliferating cell nuclear antigen 0.853221
CCND1 cyclin D1 0.848307
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.840525
MIB1 mindbomb E3 ubiquitin protein ligase 1 0.838885
PHKG1 phosphorylase kinase, gamma 1 (muscle) 0.826589
PNLIPRP1 pancreatic lipase-related protein 1 0.817565
TXNL4A thioredoxin-like 4A 0.817565
XYLT1 xylosyltransferase I 0.813052
RUNX3 runt-related transcription factor 3 0.808129
KCNIP4 Kv channel interacting protein 4 0.803205
EGFR epidermal growth factor receptor 0.783116
EPHX3 epoxide hydrolase 3 0.771661
CDKN2A cyclin-dependent kinase inhibitor 2A 0.763086
CD44 CD44 molecule (Indian blood group) 0.756156
RAB3IP RAB3A interacting protein 0.753306
ROPN1 rhophilin associated tail protein 1 0.752492
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.730976
XRN2 5'-3' exoribonuclease 2 0.719654
LALBA lactalbumin, alpha- 0.713601
INSRR insulin receptor-related receptor 0.712392
FN1 fibronectin 1 0.693499
PIP prolactin-induced protein 0.693098
SOX4 SRY (sex determining region Y)-box 4 0.692296
KRT20 keratin 20, type I 0.689492
AMY1B amylase, alpha 1B (salivary) 0.681495
AMY1A amylase, alpha 1A (salivary) 0.681495
AMY1C amylase, alpha 1C (salivary) 0.681495
ENO2 enolase 2 (gamma, neuronal) 0.676308
TRIM2 tripartite motif containing 2 0.667152
CYR61 cysteine-rich, angiogenic inducer, 61 0.662784
DYNLT3 dynein, light chain, Tctex-type 3 0.662784
FNDC1 fibronectin type III domain containing 1 0.656441
CD6 CD6 molecule 0.655254
EVX1 even-skipped homeobox 1 0.655254
POU3F3 POU class 3 homeobox 3 0.650508
TWIST2 twist family bHLH transcription factor 2 0.646165
ESR1 estrogen receptor 1 0.646165
BECN1 beclin 1, autophagy related 0.630027
CLIC6 chloride intracellular channel 6 0.624927
MMP2 matrix metallopeptidase 2 0.615921
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 0.611229
RNH1 ribonuclease/angiogenin inhibitor 1 0.605762
SOBP sine oculis binding protein homolog (Drosophila) 0.60303
SYP synaptophysin 0.6003
CD34 CD34 molecule 0.581217
PLAGL1 pleiomorphic adenoma gene-like 1 0.566054
EPT1 ethanolaminephosphotransferase 1 0.560616
RASAL1 RAS protein activator like 1 (GAP1 like) 0.558285
LIMA1 LIM domain and actin binding 1 0.554791
GPM6B glycoprotein M6B 0.552851
GBX2 gastrulation brain homeobox 2 0.542767
PDPN podoplanin 0.541992
KITLG KIT ligand 0.540055
GFAP glial fibrillary acidic protein 0.539667
ERBB3 erb-b2 receptor tyrosine kinase 3 0.537344
MKI67 marker of proliferation Ki-67 0.535796
CECR1 cat eye syndrome chromosome region, candidate 1 0.535022
AACS acetoacetyl-CoA synthetase 0.528063
EN1 engrailed homeobox 1 0.521888
MT1H metallothionein 1H 0.50689
LDLRAD4 low density lipoprotein receptor class A domain containing 4 0.500379
GSTM5 glutathione S-transferase mu 5 0.491215
IRX6 iroquois homeobox 6 0.490454
KRT15 keratin 15, type I 0.490454
EFNA1 ephrin-A1 0.48893
CNTN6 contactin 6 0.487407
LVRN laeverin 0.483224
CSNK1E casein kinase 1, epsilon 0.476393
LGALS3 lectin, galactoside-binding, soluble, 3 0.472225
BSG basigin (Ok blood group) 0.471089
PRKCI protein kinase C, iota 0.468063
ADAM9 ADAM metallopeptidase domain 9 0.461639
BEX1 brain expressed, X-linked 1 0.461261
BEX2 brain expressed X-linked 2 0.460506
USP22 ubiquitin specific peptidase 22 0.456355
NOTCH2 notch 2 0.454093
NOTCH2NL notch 2 N-terminal like 0.451454
IARS isoleucyl-tRNA synthetase 0.447687
NOTCH1 notch 1 0.447687
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.445805
TUBE1 tubulin, epsilon 1 0.445805
DOCK4 dedicator of cytokinesis 4 0.445805
TBX4 T-box 4 0.443171
DAPK1 death-associated protein kinase 1 0.442795
MMP24 matrix metallopeptidase 24 (membrane-inserted) 0.440538
TP53AIP1 tumor protein p53 regulated apoptosis inducing protein 1 0.440538
DOCK1 dedicator of cytokinesis 1 0.43941
EREG epiregulin 0.43753
PTEN phosphatase and tensin homolog 0.431519
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.431144
BIRC5 baculoviral IAP repeat containing 5 0.430017
NKX2-1 NK2 homeobox 1 0.427015
MOCS2 molybdenum cofactor synthesis 2 0.42664
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C) 0.425139
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.424389
LYZ lysozyme 0.419142
IRX3 iroquois homeobox 3 0.416147
SOX2 SRY (sex determining region Y)-box 2 0.413901
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 0.412779
FOXL1 forkhead box L1 0.410909
MYH11 myosin, heavy chain 11, smooth muscle 0.405678
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 0.404184
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.401572
KLHL21 kelch-like family member 21 0.397471
PCGF2 polycomb group ring finger 2 0.393001
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 0.389281
KDR kinase insert domain receptor 0.387051
NID1 nidogen 1 0.370368
GPC5 glypican 5 0.368888
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.368149
REG4 regenerating islet-derived family, member 4 0.367779
TNC tenascin C 0.366301
BMI1 BMI1 proto-oncogene, polycomb ring finger 0.362978
COPA coatomer protein complex, subunit alpha 0.36187
NR2F1 nuclear receptor subfamily 2, group F, member 1 0.358551
CTTN cortactin 0.356709
MMP15 matrix metallopeptidase 15 (membrane-inserted) 0.355972
KLK14 kallikrein-related peptidase 14 0.355604
ACACB acetyl-CoA carboxylase beta 0.352291
S1PR5 sphingosine-1-phosphate receptor 5 0.348246
PROM1 prominin 1 0.347511
COL9A3 collagen, type IX, alpha 3 0.344941
SPEN spen family transcriptional repressor 0.344574
ARID5B AT rich interactive domain 5B (MRF1-like) 0.341639
PITX1 paired-like homeodomain 1 0.338707
DKK2 dickkopf WNT signaling pathway inhibitor 2 0.329565
BCL2 B-cell CLL/lymphoma 2 0.328834
FLOT2 flotillin 2 0.328469
XAGE1E X antigen family, member 1E 0.32774
XAGE1B X antigen family, member 1B 0.316456
PDZD11 PDZ domain containing 11 0.31464
NGF nerve growth factor (beta polypeptide) 0.313189
PIR pirin (iron-binding nuclear protein) 0.312827
SDC2 syndecan 2 0.307033
RBM15 RNA binding motif protein 15 0.303781
TMPRSS4 transmembrane protease, serine 4 0.300894
POLB polymerase (DNA directed), beta 0.292616
TRAF2 TNF receptor-associated factor 2 0.292616
LTF lactotransferrin 0.292257
FRMD6 FERM domain containing 6 0.28831
BPIFA1 BPI fold containing family A, member 1 0.282225
C1QBP complement component 1, q subcomponent binding protein 0.27687
AQP1 aquaporin 1 (Colton blood group) 0.27687
HMGA2 high mobility group AT-hook 2 0.272241
ILK integrin-linked kinase 0.261599
EPHA2 EPH receptor A2 0.261245
SOX10 SRY (sex determining region Y)-box 10 0.260891
ANKK1 ankyrin repeat and kinase domain containing 1 0.256652
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.256299
CTNNBIP1 catenin, beta interacting protein 1 0.254183
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.254183
HES4 hes family bHLH transcription factor 4 0.253127
NRP2 neuropilin 2 0.242945
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 0.239101
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.234225
CTAG2 cancer/testis antigen 2 0.232836
HRAS Harvey rat sarcoma viral oncogene homolog 0.231448
B3GAT1 beta-1,3-glucuronyltransferase 1 0.229716
FZD7 frizzled class receptor 7 0.228679
DES desmin 0.228679
NOTCH4 notch 4 0.225573
GMNN geminin, DNA replication inhibitor 0.223853
ITGB8 integrin, beta 8 0.218715
SRY sex determining region Y 0.212271
HBA2 hemoglobin, alpha 2 0.211597
PXN paxillin 0.209918
MUC6 mucin 6, oligomeric mucus/gel-forming 0.209248
NR2F2 nuclear receptor subfamily 2, group F, member 2 0.208579
RAP1A RAP1A, member of RAS oncogene family 0.206248
DCXR dicarbonyl/L-xylulose reductase 0.205585
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.205254
KLK10 kallikrein-related peptidase 10 0.205254
NES nestin 0.204923
FGFR1 fibroblast growth factor receptor 1 0.204263
MUC1 mucin 1, cell surface associated 0.201962
SDCBP syndecan binding protein (syntenin) 0.201962
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 0.201635
BCAN brevican 0.200982
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 0.200656
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.198709
MIRLET7B microRNA let-7b 0.19742
ITGB6 integrin, beta 6 0.196139
LPIN1 lipin 1 0.192344
NADK NAD kinase 0.192031
FLOT1 flotillin 1 0.190786
TERT telomerase reverse transcriptase 0.190476
NME4 NME/NM23 nucleoside diphosphate kinase 4 0.188326
SUFU suppressor of fused homolog (Drosophila) 0.188326
NME3 NME/NM23 nucleoside diphosphate kinase 3 0.187415
ITGB7 integrin, beta 7 0.187415
NUMA1 nuclear mitotic apparatus protein 1 0.183835
NUTM1 NUT midline carcinoma, family member 1 0.182957
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 0.181222
SNAI2 snail family zinc finger 2 0.178126
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.173832
FOXE1 forkhead box E1 0.168617
PRDM2 PR domain containing 2, with ZNF domain 0.165874
SAT1 spermidine/spermine N1-acetyltransferase 1 0.165435
AZGP1 alpha-2-glycoprotein 1, zinc-binding 0.165217
MAGEA4 melanoma antigen family A4 0.161716
DCD dermcidin 0.159838
LOXL2 lysyl oxidase-like 2 0.159124
TG thyroglobulin 0.158778
HBA1 hemoglobin, alpha 1 0.158266