saga-type complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A histone acetyltransferase complex that acetylates nucleosomal H3 and H2B and is required for the expression of a subset of Pol II-transcribed genes. The budding yeast complex includes the acetyltransferase Gcn5p, several proteins of the Spt and Ada families, and several TBP-associate proteins (TAFs); analogous complexes in other species have analogous compositions, and usually contain homologs of the yeast proteins. (Gene Ontology, GO_0070461)
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Genes

142 proteins co-occuring with the saga-type complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
ATXN7 ataxin 7 1.93204
CCDC101 coiled-coil domain containing 101 1.86143
TAF8 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa 1.72745
KAT2B K(lysine) acetyltransferase 2B 1.68848
ATXN7L3 ataxin 7-like 3 1.46099
TADA2A transcriptional adaptor 2A 1.43951
TRRAP transformation/transcription domain-associated protein 1.41474
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa 1.39628
USP22 ubiquitin specific peptidase 22 1.37741
TBP TATA box binding protein 1.34883
TADA2B transcriptional adaptor 2B 1.33413
HIST2H2BF histone cluster 2, H2bf 1.28783
HIST1H2BH histone cluster 1, H2bh 1.28783
HIST3H2BB histone cluster 3, H2bb 1.28783
HIST1H2BD histone cluster 1, H2bd 1.28729
HIST1H2BC histone cluster 1, H2bc 1.28516
HIST1H2BF histone cluster 1, H2bf 1.28516
HIST1H2BA histone cluster 1, H2ba 1.28356
TADA3 transcriptional adaptor 3 1.10053
ENY2 enhancer of yellow 2 homolog (Drosophila) 1.03029
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae) 0.99956
SF3B3 splicing factor 3b, subunit 3, 130kDa 0.997595
CCDC134 coiled-coil domain containing 134 0.990736
TREX2 three prime repair exonuclease 2 0.978559
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa 0.96792
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa 0.931245
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 0.922791
H3F3A H3 histone, family 3A 0.918579
H3F3B H3 histone, family 3B (H3.3B) 0.918579
YEATS2 YEATS domain containing 2 0.902281
POLE4 polymerase (DNA-directed), epsilon 4, accessory subunit 0.863988
SUPT7L suppressor of Ty 7 (S. cerevisiae)-like 0.836892
MBIP MAP3K12 binding inhibitory protein 1 0.790106
KAT2A K(lysine) acetyltransferase 2A 0.773188
GTF2B general transcription factor IIB 0.762707
ZNF569 zinc finger protein 569 0.759069
ZNF763 zinc finger protein 763 0.759069
ZNF501 zinc finger protein 501 0.759069
ZNF629 zinc finger protein 629 0.759069
ZNF44 zinc finger protein 44 0.756799
BCL6B B-cell CLL/lymphoma 6, member B 0.750452
ZNF436 zinc finger protein 436 0.732422
GLYATL1 glycine-N-acyltransferase-like 1 0.682463
LGALS1 lectin, galactoside-binding, soluble, 1 0.675934
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 0.674196
CRX cone-rod homeobox 0.66726
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1 0.644429
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit 0.643144
ZKSCAN7 zinc finger with KRAB and SCAN domains 7 0.634159
NBPF1 neuroblastoma breakpoint family, member 1 0.616709
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa 0.597697
TCF3 transcription factor 3 0.590133
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 0.586361
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.566338
SNRPA1 small nuclear ribonucleoprotein polypeptide A' 0.558871
NR2E3 nuclear receptor subfamily 2, group E, member 3 0.558457
ZNF135 zinc finger protein 135 0.553491
PYGO2 pygopus family PHD finger 2 0.540294
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.528388
SLK STE20-like kinase 0.502693
TAF3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa 0.493371
PBX1 pre-B-cell leukemia homeobox 1 0.490944
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa 0.469203
NRL neural retina leucine zipper 0.462398
MED26 mediator complex subunit 26 0.43538
BCL6 B-cell CLL/lymphoma 6 0.421212
LRWD1 leucine-rich repeats and WD repeat domain containing 1 0.410259
HIST1H4A histone cluster 1, H4a 0.40714
HIST1H4I histone cluster 1, H4i 0.40714
HIST1H4J histone cluster 1, H4j 0.40714
HIST2H4B histone cluster 2, H4b 0.40714
HIST1H4H histone cluster 1, H4h 0.40714
HIST1H4E histone cluster 1, H4e 0.40714
HIST1H4C histone cluster 1, H4c 0.40714
HIST1H4K histone cluster 1, H4k 0.40714
HIST1H4B histone cluster 1, H4b 0.40714
HIST1H4D histone cluster 1, H4d 0.40714
HIST1H4F histone cluster 1, H4f 0.40675
HIST2H4A histone cluster 2, H4a 0.40675
HIST4H4 histone cluster 4, H4 0.40675
HIST1H4L histone cluster 1, H4l 0.40675
TCF12 transcription factor 12 0.371599
DDB1 damage-specific DNA binding protein 1, 127kDa 0.369301
RBBP5 retinoblastoma binding protein 5 0.363185
APTX aprataxin 0.357467
LGALS7B lectin, galactoside-binding, soluble, 7B 0.356324
TAF1L TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like 0.344178
RPS5 ribosomal protein S5 0.338884
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 0.324951
H3F3C H3 histone, family 3C 0.320826
ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide 0.281085
MARCKSL1 MARCKS-like 1 0.279245
MAP3K7 mitogen-activated protein kinase kinase kinase 7 0.275202
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 0.258016
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 0.248216
CAND1 cullin-associated and neddylation-dissociated 1 0.239557
TERF1 telomeric repeat binding factor (NIMA-interacting) 1 0.239557
CNOT1 CCR4-NOT transcription complex, subunit 1 0.228819
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa 0.220673
KMT2B lysine (K)-specific methyltransferase 2B 0.219265
LSM1 LSM1, U6 small nuclear RNA associated 0.214017
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.21124
DDB2 damage-specific DNA binding protein 2, 48kDa 0.210203
ISYNA1 inositol-3-phosphate synthase 1 0.192746
PNN pinin, desmosome associated protein 0.191777
CUL4A cullin 4A 0.172201
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 0.166884
WDR5 WD repeat domain 5 0.165697
KAT5 K(lysine) acetyltransferase 5 0.16233
CHD1 chromodomain helicase DNA binding protein 1 0.140893
PRC1 protein regulator of cytokinesis 1 0.139179
AGPS alkylglycerone phosphate synthase 0.135493
IL7 interleukin 7 0.133146
PTMS parathymosin 0.13093
GLI1 GLI family zinc finger 1 0.129405
OPRM1 opioid receptor, mu 1 0.127823
CUL2 cullin 2 0.12763
TCEB2 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) 0.12732
HNMT histamine N-methyltransferase 0.126477
TERT telomerase reverse transcriptase 0.125766
RFX1 regulatory factor X, 1 (influences HLA class II expression) 0.125636
CIB1 calcium and integrin binding 1 (calmyrin) 0.125251
HMGB1 high mobility group box 1 0.124872
PAX5 paired box 5 0.123027
SUMO3 small ubiquitin-like modifier 3 0.122615
TOP1 topoisomerase (DNA) I 0.122125
SUMO2 small ubiquitin-like modifier 2 0.121706
SMAD4 SMAD family member 4 0.120119
EIF6 eukaryotic translation initiation factor 6 0.118082
CUL1 cullin 1 0.117438
PPP6C protein phosphatase 6, catalytic subunit 0.117259
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme 0.117228
PPP5C protein phosphatase 5, catalytic subunit 0.1168
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 0.116707
CIITA class II, major histocompatibility complex, transactivator 0.11617
CASP7 caspase 7, apoptosis-related cysteine peptidase 0.115449
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 0.11518
HDAC3 histone deacetylase 3 0.115078
PPEF1 protein phosphatase, EF-hand calcium binding domain 1 0.115009
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.114135
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 0.113881
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial 0.112991