ruffle membrane Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description The portion of the plasma membrane surrounding a ruffle. (Gene Ontology, GO_0032587)
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Genes

54 proteins localized to the ruffle membrane cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
PDE4A phosphodiesterase 4A, cAMP-specific 0.663342
PPP1R9B protein phosphatase 1, regulatory subunit 9B 0.663342
NF2 neurofibromin 2 (merlin) 0.663342
NME1 NME/NM23 nucleoside diphosphate kinase 1 0.663342
MACF1 microtubule-actin crosslinking factor 1 0.663342
C2CD5 C2 calcium-dependent domain containing 5 0.663342
FERMT1 fermitin family member 1 0.663342
WWC1 WW and C2 domain containing 1 0.663342
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.663342
ADGRE2 adhesion G protein-coupled receptor E2 0.663342
IFIT5 interferon-induced protein with tetratricopeptide repeats 5 0.663342
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha 0.663342
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma 0.663342
RPS3 ribosomal protein S3 0.663342
MYO6 myosin VI 0.663342
FAP fibroblast activation protein, alpha 0.663342
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 0.663342
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.663342
PDE9A phosphodiesterase 9A 0.663342
SNTG1 syntrophin, gamma 1 0.663342
CLASP2 cytoplasmic linker associated protein 2 0.663342
ITGAV integrin, alpha V 0.663342
DIAPH1 diaphanous-related formin 1 0.663342
BMX BMX non-receptor tyrosine kinase 0.663342
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.663342
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.663342
EPHA2 EPH receptor A2 0.663342
KANK1 KN motif and ankyrin repeat domains 1 0.663342
AIF1 allograft inflammatory factor 1 0.663342
APC adenomatous polyposis coli 0.663342
SPATA13 spermatogenesis associated 13 0.663342
SH3YL1 SH3 and SYLF domain containing 1 0.663342
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.663342
INPP5K inositol polyphosphate-5-phosphatase K 0.663342
CIB1 calcium and integrin binding 1 (calmyrin) 0.663342
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 0.663342
ARF4 ADP-ribosylation factor 4 0.237908
PACSIN1 protein kinase C and casein kinase substrate in neurons 1 0.237908
TPM1 tropomyosin 1 (alpha) 0.237908
PLEK pleckstrin 0.237908
EPS8L2 EPS8-like 2 0.237908
EPS8 epidermal growth factor receptor pathway substrate 8 0.237908
AKT2 v-akt murine thymoma viral oncogene homolog 2 0.237908
EPS8L1 EPS8-like 1 0.237908
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.098109
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7 0.098109
TRPV4 transient receptor potential cation channel, subfamily V, member 4 0.098109
TWF1 twinfilin actin binding protein 1 0.03318
PLA2G4F phospholipase A2, group IVF 0.03318
CDKL5 cyclin-dependent kinase-like 5 0.03318
RHOA ras homolog family member A 0.03318
CDC37 cell division cycle 37 0.03318
EPB41L5 erythrocyte membrane protein band 4.1 like 5 0.03318
FGR FGR proto-oncogene, Src family tyrosine kinase 0.03318