rosiglitazone-2693 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the rosiglitazone-2693 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A1CF APOBEC1 complementation factor
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ADCK4 aarF domain containing kinase 4
AGFG1 ArfGAP with FG repeats 1
AP4S1 adaptor-related protein complex 4, sigma 1 subunit
AQP9 aquaporin 9
ARID4B AT rich interactive domain 4B (RBP1-like)
ARSB arylsulfatase B
BLZF1 basic leucine zipper nuclear factor 1
BMP7 bone morphogenetic protein 7
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C17ORF53 chromosome 17 open reading frame 53
C17ORF59 chromosome 17 open reading frame 59
CD36 CD36 molecule (thrombospondin receptor)
DCN decorin
DHRS7 dehydrogenase/reductase (SDR family) member 7
DOPEY1 dopey family member 1
EFNB2 ephrin-B2
EHD1 EH-domain containing 1
EMC3 ER membrane protein complex subunit 3
ENC1 ectodermal-neural cortex 1 (with BTB domain)
FAIM2 Fas apoptotic inhibitory molecule 2
FBXO40 F-box protein 40
FGF21 fibroblast growth factor 21
FGF4 fibroblast growth factor 4
FHL1 four and a half LIM domains 1
FKBP8 FK506 binding protein 8, 38kDa
FLOT1 flotillin 1
FOXC1 forkhead box C1
GAL galanin/GMAP prepropeptide
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GOSR2 golgi SNAP receptor complex member 2
GPATCH4 G patch domain containing 4
GPM6B glycoprotein M6B
GRIK2 glutamate receptor, ionotropic, kainate 2
HES1 hes family bHLH transcription factor 1
HOXA10 homeobox A10
HOXA11 homeobox A11
HOXB3 homeobox B3
HOXB5 homeobox B5
HRH4 histamine receptor H4
IFT122 intraflagellar transport 122
IGL immunoglobulin lambda locus
ING2 inhibitor of growth family, member 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCTD20 potassium channel tetramerization domain containing 20
KRIT1 KRIT1, ankyrin repeat containing
LBX1 ladybird homeobox 1
MAOA monoamine oxidase A
MRPL20 mitochondrial ribosomal protein L20
MTUS1 microtubule associated tumor suppressor 1
MXD1 MAX dimerization protein 1
NIPAL2 NIPA-like domain containing 2
NOV nephroblastoma overexpressed
NPR1 natriuretic peptide receptor 1
NR1H3 nuclear receptor subfamily 1, group H, member 3
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OGFR opioid growth factor receptor
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PAPPA2 pappalysin 2
PARP3 poly (ADP-ribose) polymerase family, member 3
PGAP3 post-GPI attachment to proteins 3
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLIN2 perilipin 2
POU2F2 POU class 2 homeobox 2
PPIA peptidylprolyl isomerase A (cyclophilin A)
PROL1 proline rich, lacrimal 1
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RANBP1 RAN binding protein 1
RBM42 RNA binding motif protein 42
RXRB retinoid X receptor, beta
SCARB1 scavenger receptor class B, member 1
SGMS1 sphingomyelin synthase 1
SIRT4 sirtuin 4
SLC38A7 solute carrier family 38, member 7
SMC1A structural maintenance of chromosomes 1A
SNX13 sorting nexin 13
SORBS2 sorbin and SH3 domain containing 2
SP1 Sp1 transcription factor
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STC1 stanniocalcin 1
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
THBD thrombomodulin
TRAPPC9 trafficking protein particle complex 9
TRD T cell receptor delta locus
TRPS1 trichorhinophalangeal syndrome I
TSKU tsukushi, small leucine rich proteoglycan
UBE2I ubiquitin-conjugating enzyme E2I
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
VSIG10 V-set and immunoglobulin domain containing 10
WIF1 WNT inhibitory factor 1
ZNF225 zinc finger protein 225
ZNF34 zinc finger protein 34

decreased expression

Symbol Name
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADGB androglobin
APOC4 apolipoprotein C-IV
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ARMCX4 armadillo repeat containing, X-linked 4
ASB7 ankyrin repeat and SOCS box containing 7
BTF3P12 basic transcription factor 3 pseudogene 12
CABP2 calcium binding protein 2
CASS4 Cas scaffolding protein family member 4
CBR3 carbonyl reductase 3
CCDC106 coiled-coil domain containing 106
CCDC92 coiled-coil domain containing 92
CD79B CD79b molecule, immunoglobulin-associated beta
CDHR2 cadherin-related family member 2
CDON cell adhesion associated, oncogene regulated
CFP complement factor properdin
CGA glycoprotein hormones, alpha polypeptide
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CIDEC cell death-inducing DFFA-like effector c
CLIP2 CAP-GLY domain containing linker protein 2
CNN1 calponin 1, basic, smooth muscle
CX3CR1 chemokine (C-X3-C motif) receptor 1
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DNM3 dynamin 3
DPEP2 dipeptidase 2
DSPP dentin sialophosphoprotein
ELAC1 elaC ribonuclease Z 1
ELP6 elongator acetyltransferase complex subunit 6
EXO5 exonuclease 5
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FLJ21369 uncharacterized protein FLJ21369
FOXN2 forkhead box N2
FZD4 frizzled class receptor 4
GATA6 GATA binding protein 6
GPR3 G protein-coupled receptor 3
GPRC5C G protein-coupled receptor, class C, group 5, member C
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BH histone cluster 1, H2bh
IBSP integrin-binding sialoprotein
IDI2-AS1 IDI2 antisense RNA 1
IQCC IQ motif containing C
IQSEC2 IQ motif and Sec7 domain 2
JAM3 junctional adhesion molecule 3
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KIAA1456 KIAA1456
KLHL36 kelch-like family member 36
KRT20 keratin 20, type I
LIME1 Lck interacting transmembrane adaptor 1
LOC729164 hCG1732469
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MIR22HG MIR22 host gene
MMP9 matrix metallopeptidase 9
MNX1 motor neuron and pancreas homeobox 1
MTSS1L metastasis suppressor 1-like
MX2 MX dynamin-like GTPase 2
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
PBOV1 prostate and breast cancer overexpressed 1
PCBP4 poly(rC) binding protein 4
PKD2L2 polycystic kidney disease 2-like 2
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRF1 perforin 1 (pore forming protein)
PRSS53 protease, serine, 53
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RNF126P1 ring finger protein 126 pseudogene 1
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RUSC2 RUN and SH3 domain containing 2
SCAI suppressor of cancer cell invasion
SLC16A6 solute carrier family 16, member 6
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SPON2 spondin 2, extracellular matrix protein
STAG3 stromal antigen 3
STAT5A signal transducer and activator of transcription 5A
SYNPO2L synaptopodin 2-like
SYTL2 synaptotagmin-like 2
TMEM212 transmembrane protein 212
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNS2 tensin 2
TONSL tonsoku-like, DNA repair protein
TPM3 tropomyosin 3
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TUFT1 tuftelin 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WDR25 WD repeat domain 25
ZNF177 zinc finger protein 177
ZNF219 zinc finger protein 219
ZNF408 zinc finger protein 408
ZNF428 zinc finger protein 428
ZNF669 zinc finger protein 669
ZNF711 zinc finger protein 711
ZNF749 zinc finger protein 749
ZNF85 zinc finger protein 85