ritodrine-2635 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the ritodrine-2635 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A1CF APOBEC1 complementation factor
A4GALT alpha 1,4-galactosyltransferase
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADAM23 ADAM metallopeptidase domain 23
AGBL2 ATP/GTP binding protein-like 2
AGRN agrin
AOC2 amine oxidase, copper containing 2 (retina-specific)
ARHGAP33 Rho GTPase activating protein 33
ATP11A ATPase, class VI, type 11A
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BMP6 bone morphogenetic protein 6
C14ORF1 chromosome 14 open reading frame 1
C14ORF79 chromosome 14 open reading frame 79
C1ORF95 chromosome 1 open reading frame 95
C3 complement component 3
CARD14 caspase recruitment domain family, member 14
CCKAR cholecystokinin A receptor
CCL19 chemokine (C-C motif) ligand 19
CDADC1 cytidine and dCMP deaminase domain containing 1
CDHR2 cadherin-related family member 2
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
COL5A1 collagen, type V, alpha 1
CROCC ciliary rootlet coiled-coil, rootletin
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DCAF15 DDB1 and CUL4 associated factor 15
DFNB31 deafness, autosomal recessive 31
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
EFNB3 ephrin-B3
ELOVL5 ELOVL fatty acid elongase 5
FAM134B family with sequence similarity 134, member B
FBXL7 F-box and leucine-rich repeat protein 7
FGL1 fibrinogen-like 1
FLJ11292
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GYPB glycophorin B (MNS blood group)
GZMK granzyme K (granzyme 3; tryptase II)
HAS2 hyaluronan synthase 2
HOXC5 homeobox C5
ICOSLG inducible T-cell co-stimulator ligand
IL1RL1 interleukin 1 receptor-like 1
INPP5J inositol polyphosphate-5-phosphatase J
INSR insulin receptor
IQSEC2 IQ motif and Sec7 domain 2
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LTBP2 latent transforming growth factor beta binding protein 2
MAP2K3 mitogen-activated protein kinase kinase 3
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MARK4 MAP/microtubule affinity-regulating kinase 4
MAX MYC associated factor X
MTSS1L metastasis suppressor 1-like
N4BP2L1 NEDD4 binding protein 2-like 1
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
NOP16 NOP16 nucleolar protein
NR2C1 nuclear receptor subfamily 2, group C, member 1
NUDCD3 NudC domain containing 3
PAPPA2 pappalysin 2
PCDHGB5 protocadherin gamma subfamily B, 5
PCOLCE procollagen C-endopeptidase enhancer
PDE4DIP phosphodiesterase 4D interacting protein
PITX2 paired-like homeodomain 2
POSTN periostin, osteoblast specific factor
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
PTGDS prostaglandin D2 synthase 21kDa (brain)
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RABGAP1L RAB GTPase activating protein 1-like
RANBP10 RAN binding protein 10
RASL11B RAS-like, family 11, member B
RBM48 RNA binding motif protein 48
RGS10 regulator of G-protein signaling 10
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RYR2 ryanodine receptor 2 (cardiac)
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLIT2 slit homolog 2 (Drosophila)
SPDEF SAM pointed domain containing ETS transcription factor
SPINK1 serine peptidase inhibitor, Kazal type 1
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SRSF7 serine/arginine-rich splicing factor 7
TAZ tafazzin
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRAF3IP2 TRAF3 interacting protein 2
TRIM10 tripartite motif containing 10
UPK3B uroplakin 3B
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
ZNF117 zinc finger protein 117
ZNF37BP zinc finger protein 37B, pseudogene
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ABHD4 abhydrolase domain containing 4
ACSF2 acyl-CoA synthetase family member 2
AKR1C3 aldo-keto reductase family 1, member C3
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ALPK1 alpha-kinase 1
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A
ASB9 ankyrin repeat and SOCS box containing 9
AZI2 5-azacytidine induced 2
BIRC7 baculoviral IAP repeat containing 7
C11ORF95 chromosome 11 open reading frame 95
C17ORF80 chromosome 17 open reading frame 80
C19ORF73 chromosome 19 open reading frame 73
C7ORF43 chromosome 7 open reading frame 43
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CDKL3 cyclin-dependent kinase-like 3
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHKB choline kinase beta
CHML choroideremia-like (Rab escort protein 2)
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLEC16A C-type lectin domain family 16, member A
CTSK cathepsin K
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EXOC5 exocyst complex component 5
FLCN folliculin
GAMT guanidinoacetate N-methyltransferase
GID4 GID complex subunit 4
GTF2I general transcription factor IIi
HOXC10 homeobox C10
IRF2 interferon regulatory factor 2
KLF3 Kruppel-like factor 3 (basic)
LIG4 ligase IV, DNA, ATP-dependent
LRIF1 ligand dependent nuclear receptor interacting factor 1
LRP5L low density lipoprotein receptor-related protein 5-like
LY6G6C lymphocyte antigen 6 complex, locus G6C
MECR mitochondrial trans-2-enoyl-CoA reductase
NDE1 nudE neurodevelopment protein 1
NIPAL2 NIPA-like domain containing 2
NPM3 nucleophosmin/nucleoplasmin 3
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PELI1 pellino E3 ubiquitin protein ligase 1
PEX26 peroxisomal biogenesis factor 26
PHC1 polyhomeotic homolog 1 (Drosophila)
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PLEKHO2 pleckstrin homology domain containing, family O member 2
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2
PPT2 palmitoyl-protein thioesterase 2
PRSS16 protease, serine, 16 (thymus)
PTDSS2 phosphatidylserine synthase 2
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RABL3 RAB, member of RAS oncogene family-like 3
RBBP5 retinoblastoma binding protein 5
RBL1 retinoblastoma-like 1
RCOR3 REST corepressor 3
RGS17 regulator of G-protein signaling 17
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF122 ring finger protein 122
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNF219 ring finger protein 219
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SPINK5 serine peptidase inhibitor, Kazal type 5
SSFA2 sperm specific antigen 2
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TBC1D31 TBC1 domain family, member 31
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TGFB3 transforming growth factor, beta 3
TGIF1 TGFB-induced factor homeobox 1
THBS3 thrombospondin 3
TMC7 transmembrane channel-like 7
TSPAN1 tetraspanin 1
TXLNG taxilin gamma
ULBP2 UL16 binding protein 2
WDR19 WD repeat domain 19
WDR4 WD repeat domain 4
WDR91 WD repeat domain 91
WLS wntless Wnt ligand secretion mediator
ZBTB10 zinc finger and BTB domain containing 10
ZNF141 zinc finger protein 141
ZNF324 zinc finger protein 324
ZNF446 zinc finger protein 446
ZNF492 zinc finger protein 492
ZNF552 zinc finger protein 552
ZNF573 zinc finger protein 573
ZNF574 zinc finger protein 574
ZNF675 zinc finger protein 675
ZNF767P zinc finger family member 767, pseudogene