ring stage Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description The early trophozoite in the erythrocytic stage of the life cycle of hemosporian protozoa, which after Romanovsky staining has blue cytoplasm surrounding a clear zone with a red nucleus at one side, giving the cell the appearance of a signet ring. (BRENDA Tissue and Enzyme Source Ontology, BTO_0001893)
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Genes

162 proteins co-occuring with the tissue ring stage in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
KRT7 keratin 7, type II 1.99428
KRT20 keratin 20, type I 1.96884
EML4 echinoderm microtubule associated protein like 4 1.75624
CDX2 caudal type homeobox 2 1.72534
MUC2 mucin 2, oligomeric mucus/gel-forming 1.68703
PIP prolactin-induced protein 1.67855
ALK anaplastic lymphoma receptor tyrosine kinase 1.61758
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.61659
MUC5B mucin 5B, oligomeric mucus/gel-forming 1.54777
MLH1 mutL homolog 1 1.53047
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 1.49349
MUC6 mucin 6, oligomeric mucus/gel-forming 1.48176
MUC1 mucin 1, cell surface associated 1.41583
RNF175 ring finger protein 175 1.41445
KRAS Kirsten rat sarcoma viral oncogene homolog 1.40156
MSH2 mutS homolog 2 1.3219
HRAS Harvey rat sarcoma viral oncogene homolog 1.26799
NAPSA napsin A aspartic peptidase 1.23896
TP53 tumor protein p53 1.18423
CRABP1 cellular retinoic acid binding protein 1 1.16604
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit 1.07441
CHGA chromogranin A 1.02644
ERBB2 erb-b2 receptor tyrosine kinase 2 0.99586
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase 0.98977
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 0.989335
NEUROG1 neurogenin 1 0.97285
KRT8 keratin 8, type II 0.967657
LRRN4 leucine rich repeat neuronal 4 0.961607
MSH6 mutS homolog 6 0.956859
MLANA melan-A 0.950393
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.940066
ZNF135 zinc finger protein 135 0.937917
KLK3 kallikrein-related peptidase 3 0.92805
RUNX3 runt-related transcription factor 3 0.919916
SYP synaptophysin 0.918633
CDKN2A cyclin-dependent kinase inhibitor 2A 0.89817
CALB2 calbindin 2 0.882897
KRT5 keratin 5, type II 0.877397
NKX2-1 NK2 homeobox 1 0.796458
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.794375
CAGE1 cancer antigen 1 0.766125
TG thyroglobulin 0.744214
WRN Werner syndrome, RecQ helicase-like 0.712959
UPK3B uroplakin 3B 0.696581
FGF6 fibroblast growth factor 6 0.696172
EGFR epidermal growth factor receptor 0.690451
ZNF224 zinc finger protein 224 0.680248
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 0.67821
CRTC1 CREB regulated transcription coactivator 1 0.675357
ATP4B ATPase, H+/K+ exchanging, beta polypeptide 0.66925
MAML2 mastermind-like 2 (Drosophila) 0.653807
MUC4 mucin 4, cell surface associated 0.646505
ESR1 estrogen receptor 1 0.64529
CLEC2A C-type lectin domain family 2, member A 0.624254
PTPRC protein tyrosine phosphatase, receptor type, C 0.621428
RHBDL1 rhomboid, veinlet-like 1 (Drosophila) 0.616586
GAST gastrin 0.605306
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase 0.598067
ACPP acid phosphatase, prostate 0.598067
CTBP2 C-terminal binding protein 2 0.590036
PDPN podoplanin 0.584422
ENO2 enolase 2 (gamma, neuronal) 0.578816
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 0.576816
REM1 RAS (RAD and GEM)-like GTP-binding 1 0.573616
MED23 mediator complex subunit 23 0.573616
LYZ lysozyme 0.57042
PRICKLE2 prickle homolog 2 (Drosophila) 0.566428
MSLN mesothelin 0.560449
EPB41 erythrocyte membrane protein band 4.1 0.559652
SCARB2 scavenger receptor class B, member 2 0.557661
PCNA proliferating cell nuclear antigen 0.55607
CAMTA1 calmodulin binding transcription activator 1 0.555671
DACT2 dishevelled-binding antagonist of beta-catenin 2 0.542566
HIC1 hypermethylated in cancer 1 0.539793
CD36 CD36 molecule (thrombospondin receptor) 0.529113
TFF2 trefoil factor 2 0.522405
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.519647
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 0.519253
HBA1 hemoglobin, alpha 1 0.516104
PRICKLE1 prickle homolog 1 (Drosophila) 0.506672
HBA2 hemoglobin, alpha 2 0.503141
SCARB1 scavenger receptor class B, member 1 0.488276
DSG2 desmoglein 2 0.478923
CAND1 cullin-associated and neddylation-dissociated 1 0.475034
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.46766
EGOT eosinophil granule ontogeny transcript (non-protein coding) 0.466885
FOXJ2 forkhead box J2 0.463787
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 0.462239
CD34 CD34 molecule 0.456828
ERH enhancer of rudimentary homolog (Drosophila) 0.447192
POU2F2 POU class 2 homeobox 2 0.437205
FAF1 Fas (TNFRSF6) associated factor 1 0.437205
G6PD glucose-6-phosphate dehydrogenase 0.414293
PGR progesterone receptor 0.410491
PEX2 peroxisomal biogenesis factor 2 0.410111
DAND5 DAN domain family member 5, BMP antagonist 0.405555
MCM2 minichromosome maintenance complex component 2 0.396844
CD68 CD68 molecule 0.390799
CD2BP2 CD2 (cytoplasmic tail) binding protein 2 0.386273
ETV6 ets variant 6 0.38326
DAB2IP DAB2 interacting protein 0.381003
GATA3 GATA binding protein 3 0.374993
IGF2 insulin-like growth factor 2 0.373493
SFN stratifin 0.369373
WT1 Wilms tumor 1 0.367129
LEMD3 LEM domain containing 3 0.364139
KRT14 keratin 14, type I 0.363393
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa 0.36302
MFRP membrane frizzled-related protein 0.35557
EIF3A eukaryotic translation initiation factor 3, subunit A 0.350001
MUC13 mucin 13, cell surface associated 0.345928
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.345928
TRIM47 tripartite motif containing 47 0.344818
SCN10A sodium channel, voltage gated, type X alpha subunit 0.344818
ANXA7 annexin A7 0.34371
TMPRSS2 transmembrane protease, serine 2 0.338914
GYPE glycophorin E (MNS blood group) 0.333396
CLDN18 claudin 18 0.328262
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.324605
PDXK pyridoxal (pyridoxine, vitamin B6) kinase 0.323874
MCM7 minichromosome maintenance complex component 7 0.317679
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 0.316588
ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 0.313683
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.312957
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.310059
COL14A1 collagen, type XIV, alpha 1 0.298165
NCBP1 nuclear cap binding protein subunit 1, 80kDa 0.297089
NOXO1 NADPH oxidase organizer 1 0.294581
FZD8 frizzled class receptor 8 0.293866
PEX19 peroxisomal biogenesis factor 19 0.28887
FZD10 frizzled class receptor 10 0.284962
WWTR1 WW domain containing transcription regulator 1 0.283191
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.278955
POU2F1 POU class 2 homeobox 1 0.278251
HAGH hydroxyacylglutathione hydrolase 0.2779
KIF1B kinesin family member 1B 0.274394
FZD5 frizzled class receptor 5 0.269867
ANK1 ankyrin 1, erythrocytic 0.266757
S100A9 S100 calcium binding protein A9 0.266757
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.266413
FZD9 frizzled class receptor 9 0.264011
PROP1 PROP paired-like homeobox 1 0.261284
BRCA1 breast cancer 1, early onset 0.257572
PMP2 peripheral myelin protein 2 0.254902
GRASP GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein 0.247399
DKK2 dickkopf WNT signaling pathway inhibitor 2 0.246124
FNDC3A fibronectin type III domain containing 3A 0.239007
TPP1 tripeptidyl peptidase I 0.235167
HN1 hematological and neurological expressed 1 0.234016
FZD6 frizzled class receptor 6 0.234016
KRT83 keratin 83, type II 0.230931
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 0.230656
ATF1 activating transcription factor 1 0.230382
SFRP5 secreted frizzled-related protein 5 0.229568
TFF3 trefoil factor 3 (intestinal) 0.227707
ERBB3 erb-b2 receptor tyrosine kinase 3 0.227186
RAB5A RAB5A, member RAS oncogene family 0.224893
PLAG1 pleiomorphic adenoma gene 1 0.223906
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 0.220831
SYK spleen tyrosine kinase 0.220152
DHFR dihydrofolate reductase 0.214765
MED12 mediator complex subunit 12 0.212936