response to oxidative stress Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. (Gene Ontology, GO_0006979)
External Link http://amigo.geneontology.org/amigo/term/GO:0006979
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Genes

285 genes participating in the response to oxidative stress biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ADA adenosine deaminase
ADAM9 ADAM metallopeptidase domain 9
ADIPOQ adiponectin, C1Q and collagen domain containing
ADNP2 ADNP homeobox 2
ADPRHL2 ADP-ribosylhydrolase like 2
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
AIF1 allograft inflammatory factor 1
AKR1C3 aldo-keto reductase family 1, member C3
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ALS2 amyotrophic lateral sclerosis 2 (juvenile)
ANGPTL7 angiopoietin-like 7
ANXA1 annexin A1
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APOD apolipoprotein D
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
APTX aprataxin
AQP1 aquaporin 1 (Colton blood group)
AQP8 aquaporin 8
AREG amphiregulin
ARG1 arginase 1
ATOX1 antioxidant 1 copper chaperone
ATP7A ATPase, Cu++ transporting, alpha polypeptide
ATRN attractin
AXL AXL receptor tyrosine kinase
BAD BCL2-associated agonist of cell death
BAK1 BCL2-antagonist/killer 1
BCL2 B-cell CLL/lymphoma 2
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BTK Bruton agammaglobulinemia tyrosine kinase
CA3 carbonic anhydrase III
CAT catalase
CCL19 chemokine (C-C motif) ligand 19
CCR7 chemokine (C-C motif) receptor 7
CCS copper chaperone for superoxide dismutase
CD36 CD36 molecule (thrombospondin receptor)
CD38 CD38 molecule
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CHUK conserved helix-loop-helix ubiquitous kinase
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
COL1A1 collagen, type I, alpha 1
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
CPEB2 cytoplasmic polyadenylation element binding protein 2
CRYAB crystallin, alpha B
CRYGD crystallin, gamma D
CYCS cytochrome c, somatic
CYGB cytoglobin
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DDIAS DNA damage-induced apoptosis suppressor
DGKK diacylglycerol kinase, kappa
DHCR24 24-dehydrocholesterol reductase
DHRS2 dehydrogenase/reductase (SDR family) member 2
DPEP1 dipeptidase 1 (renal)
DUOX1 dual oxidase 1
DUOX2 dual oxidase 2
DUSP1 dual specificity phosphatase 1
ECT2 epithelial cell transforming 2
EDN1 endothelin 1
EGFR epidermal growth factor receptor
EGLN1 egl-9 family hypoxia-inducible factor 1
EPX eosinophil peroxidase
ERCC1 excision repair cross-complementation group 1
ERCC2 excision repair cross-complementation group 2
ERCC3 excision repair cross-complementation group 3
ERCC6 excision repair cross-complementation group 6
ERCC8 excision repair cross-complementation group 8
ERO1L ERO1-like (S. cerevisiae)
ETFDH electron-transferring-flavoprotein dehydrogenase
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
ETV5 ets variant 5
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FABP1 fatty acid binding protein 1, liver
FER fer (fps/fes related) tyrosine kinase
FGF8 fibroblast growth factor 8 (androgen-induced)
FKBP1B FK506 binding protein 1B, 12.6 kDa
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSL1 FOS-like antigen 1
FOXO1 forkhead box O1
FOXO3 forkhead box O3
FXN frataxin
G6PD glucose-6-phosphate dehydrogenase
GAB1 GRB2-associated binding protein 1
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
GJB2 gap junction protein, beta 2, 26kDa
GLRX2 glutaredoxin 2
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GPX1 glutathione peroxidase 1
GPX2 glutathione peroxidase 2
GPX3 glutathione peroxidase 3
GPX4 glutathione peroxidase 4
GPX5 glutathione peroxidase 5
GPX6 glutathione peroxidase 6
GPX7 glutathione peroxidase 7
GPX8 glutathione peroxidase 8 (putative)
GSR glutathione reductase
GSS glutathione synthetase
GSTP1 glutathione S-transferase pi 1
HAO1 hydroxyacid oxidase (glycolate oxidase) 1
HBB hemoglobin, beta
HDAC6 histone deacetylase 6
HMOX1 heme oxygenase 1
HP haptoglobin
HTRA2 HtrA serine peptidase 2
HYAL1 hyaluronoglucosaminidase 1
HYAL2 hyaluronoglucosaminidase 2
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IL18BP interleukin 18 binding protein
IL6 interleukin 6
IPCEF1 interaction protein for cytohesin exchange factors 1
JAK2 Janus kinase 2
JUN jun proto-oncogene
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2
KDM6B lysine (K)-specific demethylase 6B
KLF2 Kruppel-like factor 2
KLF4 Kruppel-like factor 4 (gut)
KPNA4 karyopherin alpha 4 (importin alpha 3)
KRT1 keratin 1, type II
LCK LCK proto-oncogene, Src family tyrosine kinase
LCN2 lipocalin 2
LIAS lipoic acid synthetase
LIG1 ligase I, DNA, ATP-dependent
LONP1 lon peptidase 1, mitochondrial
LPO lactoperoxidase
LRRK2 leucine-rich repeat kinase 2
MAP2K1 mitogen-activated protein kinase kinase 1
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAPK7 mitogen-activated protein kinase 7
MAPK8 mitogen-activated protein kinase 8
MB myoglobin
MBL2 mannose-binding lectin (protein C) 2, soluble
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MGMT O-6-methylguanine-DNA methyltransferase
MGST1 microsomal glutathione S-transferase 1
MICB MHC class I polypeptide-related sequence B
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP3 matrix metallopeptidase 3
MPO myeloperoxidase
MPV17 MpV17 mitochondrial inner membrane protein
MSRA methionine sulfoxide reductase A
MSRB1 methionine sulfoxide reductase B1
MSRB2 methionine sulfoxide reductase B2
MSRB3 methionine sulfoxide reductase B3
MT3 metallothionein 3
MTF1 metal-regulatory transcription factor 1
NAPRT nicotinate phosphoribosyltransferase
NDUFA12 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa
NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
NEIL1 nei endonuclease VIII-like 1 (E. coli)
NET1 neuroepithelial cell transforming 1
NFE2L1 nuclear factor, erythroid 2-like 1
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NGF nerve growth factor (beta polypeptide)
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1
OGG1 8-oxoguanine DNA glycosylase
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OSER1 oxidative stress responsive serine-rich 1
OXR1 oxidation resistance 1
OXSR1 oxidative stress responsive 1
P4HB prolyl 4-hydroxylase, beta polypeptide
PARK2 parkin RBR E3 ubiquitin protein ligase
PARK7 parkinson protein 7
PARP1 poly (ADP-ribose) polymerase 1
PAX2 paired box 2
PCGF2 polycomb group ring finger 2
PDCD10 programmed cell death 10
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PDLIM1 PDZ and LIM domain 1
PINK1 PTEN induced putative kinase 1
PKD2 polycystic kidney disease 2 (autosomal dominant)
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
PLK3 polo-like kinase 3
PNKP polynucleotide kinase 3'-phosphatase
PNPT1 polyribonucleotide nucleotidyltransferase 1
PON2 paraoxonase 2
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta
PPIF peptidylprolyl isomerase F
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PRDX1 peroxiredoxin 1
PRDX2 peroxiredoxin 2
PRDX3 peroxiredoxin 3
PRDX5 peroxiredoxin 5
PRDX6 peroxiredoxin 6
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKD1 protein kinase D1
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator
PRNP prion protein
PSEN1 presenilin 1
PSIP1 PC4 and SFRS1 interacting protein 1
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2B protein tyrosine kinase 2 beta
PTPRK protein tyrosine phosphatase, receptor type, K
PTPRN protein tyrosine phosphatase, receptor type, N
PXDN peroxidasin
PXDNL peroxidasin-like
PXN paxillin
PYCR1 pyrroline-5-carboxylate reductase 1
RAD52 RAD52 homolog (S. cerevisiae)
RBM11 RNA binding motif protein 11
RCAN2 regulator of calcineurin 2
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RGS14 regulator of G-protein signaling 14
RHOB ras homolog family member B
ROMO1 reactive oxygen species modulator 1
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
S100A7 S100 calcium binding protein A7
SCARA3 scavenger receptor class A, member 3
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SDC1 syndecan 1
SELK selenoprotein K
SEPP1 selenoprotein P, plasma, 1
SETX senataxin
SFTPC surfactant protein C
SGK2 serum/glucocorticoid regulated kinase 2
SIRT1 sirtuin 1
SIRT2 sirtuin 2
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SOD3 superoxide dismutase 3, extracellular
SPHK1 sphingosine kinase 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRXN1 sulfiredoxin 1
STAR steroidogenic acute regulatory protein
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STC2 stanniocalcin 2
STK24 serine/threonine kinase 24
STK25 serine/threonine kinase 25
STK26 serine/threonine protein kinase 26
STX2 syntaxin 2
STX4 syntaxin 4
TACR1 tachykinin receptor 1
TAT tyrosine aminotransferase
THBS1 thrombospondin 1
TMEM161A transmembrane protein 161A
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TOR1A torsin family 1, member A (torsin A)
TP53INP1 tumor protein p53 inducible nuclear protein 1
TPM1 tropomyosin 1 (alpha)
TPO thyroid peroxidase
TRAF2 TNF receptor-associated factor 2
TRPA1 transient receptor potential cation channel, subfamily A, member 1
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TXN thioredoxin
TXN2 thioredoxin 2
TXNDC2 thioredoxin domain containing 2 (spermatozoa)
TXNDC8 thioredoxin domain containing 8 (spermatozoa)
TXNIP thioredoxin interacting protein
TXNL1 thioredoxin-like 1
TXNRD1 thioredoxin reductase 1
TXNRD2 thioredoxin reductase 2
UCN urocortin
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UCP3 uncoupling protein 3 (mitochondrial, proton carrier)
VIMP VCP-interacting membrane selenoprotein
VKORC1L1 vitamin K epoxide reductase complex, subunit 1-like 1
VNN1 vanin 1
VRK2 vaccinia related kinase 2
WRN Werner syndrome, RecQ helicase-like
XPA xeroderma pigmentosum, complementation group A
ZNF277 zinc finger protein 277
ZNF580 zinc finger protein 580