response to ionizing radiation Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays. (Gene Ontology, GO_0010212)
External Link http://amigo.geneontology.org/amigo/term/GO:0010212
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Genes

127 genes participating in the response to ionizing radiation biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5
AEN apoptosis enhancing nuclease
ANXA1 annexin A1
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
ATM ATM serine/threonine kinase
ATR ATR serine/threonine kinase
BABAM1 BRISC and BRCA1 A complex member 1
BAK1 BCL2-antagonist/killer 1
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BLM Bloom syndrome, RecQ helicase-like
BRAT1 BRCA1-associated ATM activator 1
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BRCC3 BRCA1/BRCA2-containing complex, subunit 3
BRE brain and reproductive organ-expressed (TNFRSF1A modulator)
BRSK1 BR serine/threonine kinase 1
C10ORF90 chromosome 10 open reading frame 90
CCL2 chemokine (C-C motif) ligand 2
CCL7 chemokine (C-C motif) ligand 7
CCND1 cyclin D1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHEK2 checkpoint kinase 2
CLK2 CDC-like kinase 2
CLOCK clock circadian regulator
CRYAB crystallin, alpha B
CXCL10 chemokine (C-X-C motif) ligand 10
CYBA cytochrome b-245, alpha polypeptide
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DCLRE1C DNA cross-link repair 1C
DCUN1D3 DCN1, defective in cullin neddylation 1, domain containing 3
DDIAS DNA damage-induced apoptosis suppressor
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
ECT2 epithelial cell transforming 2
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EGR1 early growth response 1
ELK1 ELK1, member of ETS oncogene family
ERCC1 excision repair cross-complementation group 1
ERCC6 excision repair cross-complementation group 6
ERCC8 excision repair cross-complementation group 8
EYA1 EYA transcriptional coactivator and phosphatase 1
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM175A family with sequence similarity 175, member A
FANCD2 Fanconi anemia, complementation group D2
FIGNL1 fidgetin-like 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GATA3 GATA binding protein 3
GPX1 glutathione peroxidase 1
GRB2 growth factor receptor-bound protein 2
GTF2H5 general transcription factor IIH, polypeptide 5
H2AFX H2A histone family, member X
HUS1 HUS1 checkpoint homolog (S. pombe)
ICAM1 intercellular adhesion molecule 1
IFI16 interferon, gamma-inducible protein 16
IKBIP IKBKB interacting protein
INIP INTS3 and NABP interacting protein
INO80 INO80 complex subunit
INTS3 integrator complex subunit 3
INTS7 integrator complex subunit 7
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
KAT5 K(lysine) acetyltransferase 5
KRT14 keratin 14, type I
LIG4 ligase IV, DNA, ATP-dependent
LZIC leucine zipper and CTNNBIP1 domain containing
MAPK14 mitogen-activated protein kinase 14
MEN1 multiple endocrine neoplasia I
MGMT O-6-methylguanine-DNA methyltransferase
MSH2 mutS homolog 2
MTA1 metastasis associated 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NABP1 nucleic acid binding protein 1
NABP2 nucleic acid binding protein 2
NEK1 NIMA-related kinase 1
NET1 neuroepithelial cell transforming 1
NHEJ1 nonhomologous end-joining factor 1
NIPBL Nipped-B homolog (Drosophila)
NOX4 NADPH oxidase 4
PAXIP1 PAX interacting (with transcription-activation domain) protein 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PML promyelocytic leukemia
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKDC protein kinase, DNA-activated, catalytic polypeptide
RAD1 RAD1 checkpoint DNA exonuclease
RAD51 RAD51 recombinase
RAD51AP1 RAD51 associated protein 1
RAD54L RAD54-like (S. cerevisiae)
RAD9A RAD9 homolog A (S. pombe)
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase
RFWD3 ring finger and WD repeat domain 3
RHNO1 RAD9-HUS1-RAD1 interacting nuclear orphan 1
RHOB ras homolog family member B
RNF168 ring finger protein 168, E3 ubiquitin protein ligase
RNF8 ring finger protein 8, E3 ubiquitin protein ligase
RRM1 ribonucleotide reductase M1
SFRP1 secreted frizzled-related protein 1
SFRP2 secreted frizzled-related protein 2
SIRT1 sirtuin 1
SNAI2 snail family zinc finger 2
SOD2 superoxide dismutase 2, mitochondrial
SPIDR scaffolding protein involved in DNA repair
STAR steroidogenic acute regulatory protein
STK11 serine/threonine kinase 11
SWI5 SWI5 recombination repair homolog (yeast)
THBD thrombomodulin
TICRR TOPBP1-interacting checkpoint and replication regulator
TIGAR TP53 induced glycolysis regulatory phosphatase
TLK2 tousled-like kinase 2
TMEM109 transmembrane protein 109
TOPBP1 topoisomerase (DNA) II binding protein 1
TP53 tumor protein p53
TP53BP2 tumor protein p53 binding protein 2
TP63 tumor protein p63
TP73 tumor protein p73
TRIM13 tripartite motif containing 13
TSPYL5 TSPY-like 5
UIMC1 ubiquitin interaction motif containing 1
USP28 ubiquitin specific peptidase 28
VCAM1 vascular cell adhesion molecule 1
WRN Werner syndrome, RecQ helicase-like
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
XRRA1 X-ray radiation resistance associated 1
YAP1 Yes-associated protein 1