renal tubule atrophy Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description acquired diminution of the size of the loops of Henle, the proximal convoluted tubule or the distal convoluted tubule associated with wasting as from death and reabsorbtion of cells, diminished cellular proliferation, decreased cellular volume, pressure, ischemia, malnutrition, reduced function or malfunction, or hormonal changes (Mammalian Phenotype Ontology, MP_0011346)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0011346
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Genes

22 gene mutations causing the renal tubule atrophy phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
AGA aspartylglucosaminidase
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
APRT adenine phosphoribosyltransferase
CD1D CD1d molecule
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
COL4A4 collagen, type IV, alpha 4
COL4A5 collagen, type IV, alpha 5
DCN decorin
DKC1 dyskeratosis congenita 1, dyskerin
G6PC glucose-6-phosphatase, catalytic subunit
GLIS2 GLIS family zinc finger 2
GRHPR glyoxylate reductase/hydroxypyruvate reductase
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
LGMN legumain
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
REN renin
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
UOX urate oxidase, pseudogene