renal medulla Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description The inner section of the kidney. (BRENDA Tissue and Enzyme Source Ontology, BTO_0001167)
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Genes

339 proteins co-occuring with the tissue renal medulla in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
AQP2 aquaporin 2 (collecting duct) 2.36314
SLC14A2 solute carrier family 14 (urea transporter), member 2 2.10752
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 1.86875
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 1.83118
DNAH8 dynein, axonemal, heavy chain 8 1.82759
AVP arginine vasopressin 1.71092
AQP1 aquaporin 1 (Colton blood group) 1.53862
AQP3 aquaporin 3 (Gill blood group) 1.48927
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) 1.41906
REN renin 1.3933
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 1.33545
NPPA natriuretic peptide A 1.31289
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2 1.21535
SLC5A4 solute carrier family 5 (glucose activated ion channel), member 4 1.21446
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.21268
TALDO1 transaldolase 1 1.20956
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 1.15185
NOS3 nitric oxide synthase 3 (endothelial cell) 1.14343
KNG1 kininogen 1 1.12084
AVPR2 arginine vasopressin receptor 2 1.10535
ACE angiotensin I converting enzyme 1.06426
CLCNKA chloride channel, voltage-sensitive Ka 1.03083
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 1.02776
EGLN1 egl-9 family hypoxia-inducible factor 1 1.00981
EDNRA endothelin receptor type A 0.995425
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2 0.990204
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12 0.938777
EDN1 endothelin 1 0.936199
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.929335
CYS1 cystin 1 0.919916
NOS1 nitric oxide synthase 1 (neuronal) 0.829872
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7 0.824431
CHDH choline dehydrogenase 0.801042
SQRDL sulfide quinone reductase-like (yeast) 0.799375
HMOX1 heme oxygenase 1 0.795208
AQP4 aquaporin 4 0.792293
PLA2G1B phospholipase A2, group IB (pancreas) 0.783141
SORD sorbitol dehydrogenase 0.778155
HSPA4 heat shock 70kDa protein 4 0.766125
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 0.76364
CTXN2 cortexin 2 0.744214
ATP11A ATPase, class VI, type 11A 0.743389
REL v-rel avian reticuloendotheliosis viral oncogene homolog 0.741327
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 0.740503
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12 0.737618
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.735971
COL5A3 collagen, type V, alpha 3 0.728152
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) 0.726097
RAD18 RAD18 E3 ubiquitin protein ligase 0.719934
ALB albumin 0.711729
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.70927
BHMT betaine--homocysteine S-methyltransferase 0.697399
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.694537
PHLDA3 pleckstrin homology-like domain, family A, member 3 0.683919
SCNN1B sodium channel, non voltage gated 1 beta subunit 0.683103
SOD2 superoxide dismutase 2, mitochondrial 0.66925
CUL5 cullin 5 0.667622
SFMBT2 Scm-like with four mbt domains 2 0.655836
TSC22D2 TSC22 domain family, member 2 0.655498
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 0.646505
TSC22D4 TSC22 domain family, member 4 0.642926
AFMID arylformamidase 0.642858
EDNRB endothelin receptor type B 0.638809
GTF2H5 general transcription factor IIH, polypeptide 5 0.629506
CAT catalase 0.623043
HYAL4 hyaluronoglucosaminidase 4 0.597263
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 0.596058
TINAG tubulointerstitial nephritis antigen 0.595656
SLC9A6 solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 0.59405
NR3C2 nuclear receptor subfamily 3, group C, member 2 0.592444
PGF placental growth factor 0.591641
FXYD4 FXYD domain containing ion transport regulator 4 0.587629
CHEK1 checkpoint kinase 1 0.587629
IP6K1 inositol hexakisphosphate kinase 1 0.583621
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.581618
PTGES prostaglandin E synthase 0.580818
UTS2 urotensin 2 0.580017
SH3TC2 SH3 domain and tetratricopeptide repeats 2 0.579617
MME membrane metallo-endopeptidase 0.562042
HSPA1A heat shock 70kDa protein 1A 0.556865
CDO1 cysteine dioxygenase type 1 0.55408
EGR1 early growth response 1 0.552888
NPR1 natriuretic peptide receptor 1 0.549709
HSPA4L heat shock 70kDa protein 4-like 0.540188
PTGIS prostaglandin I2 (prostacyclin) synthase 0.537416
AGTR1 angiotensin II receptor, type 1 0.53346
MGAM maltase-glucoamylase 0.533065
H2AFX H2A histone family, member X 0.532274
RNASEH2A ribonuclease H2, subunit A 0.531484
SCCPDH saccharopine dehydrogenase (putative) 0.522011
SLC4A5 solute carrier family 4 (sodium bicarbonate cotransporter), member 5 0.516497
PTGDS prostaglandin D2 synthase 21kDa (brain) 0.514136
LEP leptin 0.511384
UTS2B urotensin 2B 0.511384
CES3 carboxylesterase 3 0.510206
IP6K2 inositol hexakisphosphate kinase 2 0.509027
HN1L hematological and neurological expressed 1-like 0.502357
COMMD1 copper metabolism (Murr1) domain containing 1 0.497657
UTS2R urotensin 2 receptor 0.496483
PTH parathyroid hormone 0.495701
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 0.489057
PAPPA2 pappalysin 2 0.487886
CDON cell adhesion associated, oncogene regulated 0.487496
COL12A1 collagen, type XII, alpha 1 0.485545
GUCY2C guanylate cyclase 2C 0.483986
TERF2 telomeric repeat binding factor 2 0.477756
CRYAB crystallin, alpha B 0.475812
ECE1 endothelin converting enzyme 1 0.474258
MLYCD malonyl-CoA decarboxylase 0.471927
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 0.468824
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.466885
ASTN1 astrotactin 1 0.459145
PKM pyruvate kinase, muscle 0.455284
CNGA1 cyclic nucleotide gated channel alpha 1 0.450657
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) 0.444884
TSC22D1 TSC22 domain family, member 1 0.437652
PRB3 proline-rich protein BstNI subfamily 3 0.424581
SLC4A10 solute carrier family 4, sodium bicarbonate transporter, member 10 0.423054
WNT7B wingless-type MMTV integration site family, member 7B 0.422673
CYP4A22 cytochrome P450, family 4, subfamily A, polypeptide 22 0.417337
FXYD5 FXYD domain containing ion transport regulator 5 0.416576
PKLR pyruvate kinase, liver and RBC 0.415814
OSTF1 osteoclast stimulating factor 1 0.414166
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.413912
CLDN14 claudin 14 0.412771
HOXB7 homeobox B7 0.411251
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 0.410111
COL8A1 collagen, type VIII, alpha 1 0.407832
GRIN3B glutamate receptor, ionotropic, N-methyl-D-aspartate 3B 0.407453
CLDN10 claudin 10 0.406315
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.402144
DNM3 dynamin 3 0.399492
SLC26A7 solute carrier family 26 (anion exchanger), member 7 0.395331
SLC4A11 solute carrier family 4, sodium borate transporter, member 11 0.387027
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.386273
RBMS2 RNA binding motif, single stranded interacting protein 2 0.384766
NPHP3 nephronophthisis 3 (adolescent) 0.38163
DNPEP aspartyl aminopeptidase 0.380627
EPRS glutamyl-prolyl-tRNA synthetase 0.380251
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8 0.379875
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.378748
CLNS1A chloride channel, nucleotide-sensitive, 1A 0.378372
AASS aminoadipate-semialdehyde synthase 0.378372
ADD3 adducin 3 (gamma) 0.376494
INS insulin 0.373118
GPX5 glutathione peroxidase 5 0.368998
ADCY2 adenylate cyclase 2 (brain) 0.368624
GADD45A growth arrest and DNA-damage-inducible, alpha 0.366754
GPX4 glutathione peroxidase 4 0.365633
MATN2 matrilin 2 0.363766
GYS2 glycogen synthase 2 (liver) 0.360782
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20 0.360409
SNAPIN SNAP-associated protein 0.358546
ATM ATM serine/threonine kinase 0.35743
GPX1 glutathione peroxidase 1 0.354455
SULT4A1 sulfotransferase family 4A, member 1 0.354084
COL5A2 collagen, type V, alpha 2 0.352598
TBK1 TANK-binding kinase 1 0.350001
ACAA2 acetyl-CoA acyltransferase 2 0.346668
GATA2 GATA binding protein 2 0.344818
WEE1 WEE1 G2 checkpoint kinase 0.341495
NPTXR neuronal pentraxin receptor 0.33744
GNAS GNAS complex locus 0.332661
ACE2 angiotensin I converting enzyme 2 0.329361
CALCA calcitonin-related polypeptide alpha 0.320956
ATF2 activating transcription factor 2 0.318649
NPR3 natriuretic peptide receptor 3 0.318407
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1 0.318042
SLC22A12 solute carrier family 22 (organic anion/urate transporter), member 12 0.317315
MAPK9 mitogen-activated protein kinase 9 0.317194
EDN3 endothelin 3 0.316951
LDLRAD4 low density lipoprotein receptor class A domain containing 4 0.316467
DDIT3 DNA-damage-inducible transcript 3 0.315498
EPHB6 EPH receptor B6 0.311507
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7 0.306083
COLEC12 collectin sub-family member 12 0.302118
SS18 synovial sarcoma translocation, chromosome 18 0.302118
BMP7 bone morphogenetic protein 7 0.30038
SLC19A2 solute carrier family 19 (thiamine transporter), member 2 0.298883
NEK8 NIMA-related kinase 8 0.298225
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 0.295655
SLC9A9 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9 0.294939
BSND barttin CLCNK-type chloride channel accessory beta subunit 0.290652
NPHP1 nephronophthisis 1 (juvenile) 0.280423
PTGER3 prostaglandin E receptor 3 (subtype EP3) 0.280012
SLC4A2 solute carrier family 4 (anion exchanger), member 2 0.2779
ADD2 adducin 2 (beta) 0.276495
ARHGAP32 Rho GTPase activating protein 32 0.274394
LPCAT3 lysophosphatidylcholine acyltransferase 3 0.272649
INVS inversin 0.271314
NLRP12 NLR family, pyrin domain containing 12 0.271256
NPPC natriuretic peptide C 0.270561
CORO1A coronin, actin binding protein, 1A 0.268137
GYS1 glycogen synthase 1 (muscle) 0.267102
ACTB actin, beta 0.266069
ADM adrenomedullin 0.266069
CCNA2 cyclin A2 0.263327
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) 0.261624
ENPEP glutamyl aminopeptidase (aminopeptidase A) 0.259929
PRCP prolylcarboxypeptidase (angiotensinase C) 0.258917
ACTG1 actin gamma 1 0.249977
RHBG Rh family, B glycoprotein (gene/pseudogene) 0.249869
PISD phosphatidylserine decarboxylase 0.249653
ATP7A ATPase, Cu++ transporting, alpha polypeptide 0.249006
AMY2A amylase, alpha 2A (pancreatic) 0.244545
RENBP renin binding protein 0.243605
WNT9B wingless-type MMTV integration site family, member 9B 0.241746
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 0.24052
PDE7A phosphodiesterase 7A 0.239007
NOS2 nitric oxide synthase 2, inducible 0.236627
STXBP2 syntaxin binding protein 2 0.236137
PTGES2 prostaglandin E synthase 2 0.231206
COL5A1 collagen, type V, alpha 1 0.231206
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 0.230656
ALPPL2 alkaline phosphatase, placental-like 2 0.229839
CHRM3 cholinergic receptor, muscarinic 3 0.229568
ALPL alkaline phosphatase, liver/bone/kidney 0.229299
GCG glucagon 0.229032
ALPP alkaline phosphatase, placental 0.228764
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 0.227186
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 0.227186
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6 0.226926
TSC22D3 TSC22 domain family, member 3 0.223825
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11 0.22246
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha 0.217139
MZF1 myeloid zinc finger 1 0.216325
SOX18 SRY (sex determining region Y)-box 18 0.214388
AK2 adenylate kinase 2 0.213471
MET MET proto-oncogene, receptor tyrosine kinase 0.206919
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6 0.206299
PKD2 polycystic kidney disease 2 (autosomal dominant) 0.205241
NSF N-ethylmaleimide-sensitive factor 0.204272
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive) 0.202857
WNK4 WNK lysine deficient protein kinase 4 0.201788
STX7 syntaxin 7 0.200566
ADCY6 adenylate cyclase 6 0.199903
PURB purine-rich element binding protein B 0.199595
GRK4 G protein-coupled receptor kinase 4 0.19899
CLCA4 chloride channel accessory 4 0.198661
NUP88 nucleoporin 88kDa 0.198487
KIF3B kinesin family member 3B 0.198331
CLCA2 chloride channel accessory 2 0.198017
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa 0.197952
CFLAR CASP8 and FADD-like apoptosis regulator 0.197826
STX4 syntaxin 4 0.197739
MPDZ multiple PDZ domain protein 0.197464
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 0.19742
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 0.19713
BTC betacellulin 0.197084
MC3R melanocortin 3 receptor 0.196996
GPC4 glypican 4 0.196947
CLCA1 chloride channel accessory 1 0.196626
BMPR1A bone morphogenetic protein receptor, type IA 0.196433
MAP2K1 mitogen-activated protein kinase kinase 1 0.196005
FCGRT Fc fragment of IgG, receptor, transporter, alpha 0.195942
PLS3 plastin 3 0.195921
PDE5A phosphodiesterase 5A, cGMP-specific 0.195559
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.195437
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.195437
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.195415
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 0.195355
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 0.194929
CNTN1 contactin 1 0.194454
SHB Src homology 2 domain containing adaptor protein B 0.194153
SNAP25 synaptosomal-associated protein, 25kDa 0.193794
APOPT1 apoptogenic 1, mitochondrial 0.193785
CA2 carbonic anhydrase II 0.193721
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 0.193353
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.193188
PKD1 polycystic kidney disease 1 (autosomal dominant) 0.19297
ADRA2B adrenoceptor alpha 2B 0.19292
STX1A syntaxin 1A (brain) 0.192433
MC5R melanocortin 5 receptor 0.192422
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 0.192369
NLE1 notchless homolog 1 (Drosophila) 0.192332
RNPEP arginyl aminopeptidase (aminopeptidase B) 0.192153
VAMP3 vesicle-associated membrane protein 3 0.192153
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1 0.191875
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.191796
GPC1 glypican 1 0.190518
WNK1 WNK lysine deficient protein kinase 1 0.190126
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) 0.189093
CIB1 calcium and integrin binding 1 (calmyrin) 0.188599
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 0.188476
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7 0.188305
AKAP13 A kinase (PRKA) anchor protein 13 0.188242
MC2R melanocortin 2 receptor (adrenocorticotropic hormone) 0.187823
SCNN1G sodium channel, non voltage gated 1 gamma subunit 0.187774
CTSH cathepsin H 0.187757
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric 0.18749
ANXA4 annexin A4 0.18706
MYH9 myosin, heavy chain 9, non-muscle 0.186262
ADRA2A adrenoceptor alpha 2A 0.185899
AMPD2 adenosine monophosphate deaminase 2 0.184577
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.18428
CCNG1 cyclin G1 0.184203
PRSS8 protease, serine, 8 0.184158
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 0.184079
TSKU tsukushi, small leucine rich proteoglycan 0.184045
PDE1A phosphodiesterase 1A, calmodulin-dependent 0.18356
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1 0.183477
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 0.182644
ZFYVE9 zinc finger, FYVE domain containing 9 0.181981
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 0.181724
P2RY2 purinergic receptor P2Y, G-protein coupled, 2 0.181697
GPC3 glypican 3 0.18114
SCN10A sodium channel, voltage gated, type X alpha subunit 0.179855
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 0.179792
TRPC3 transient receptor potential cation channel, subfamily C, member 3 0.179585
ILK integrin-linked kinase 0.178418
ADCY5 adenylate cyclase 5 0.178313
GADD45G growth arrest and DNA-damage-inducible, gamma 0.178189
TRPC6 transient receptor potential cation channel, subfamily C, member 6 0.17724
AREG amphiregulin 0.176504
RER1 retention in endoplasmic reticulum sorting receptor 1 0.176404
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 0.176182
ADCY3 adenylate cyclase 3 0.175647
FADS2 fatty acid desaturase 2 0.174784
DLD dihydrolipoamide dehydrogenase 0.174425
SOX17 SRY (sex determining region Y)-box 17 0.174104
RAD50 RAD50 homolog (S. cerevisiae) 0.173965
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 0.173611
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 0.172351
UMOD uromodulin 0.17225
CALCR calcitonin receptor 0.170604
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 0.170088
PTMS parathymosin 0.169321
CAV3 caveolin 3 0.169168
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2 0.168425
NOX1 NADPH oxidase 1 0.167818
LGALS4 lectin, galactoside-binding, soluble, 4 0.167786
CXCR2 chemokine (C-X-C motif) receptor 2 0.166098
GRB2 growth factor receptor-bound protein 2 0.165744
NOX4 NADPH oxidase 4 0.16079
PROM1 prominin 1 0.159054
PPARD peroxisome proliferator-activated receptor delta 0.158914
MUT methylmalonyl CoA mutase 0.153729
SGK1 serum/glucocorticoid regulated kinase 1 0.153188
MLX MLX, MAX dimerization protein 0.148628